Infantile cortical hyperostosis

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Infantile cortical hyperostosis
Synonyms	Caffey disease, Caffey-Silverman syndrome
Pronounce	N/A
Specialty	N/A
Symptoms	Fever, irritability, swelling of soft tissues, bone changes
Complications	Deformity of bones, pain
Onset	Typically in infancy
Duration	Self-limiting, usually resolves by age 2
Types	N/A
Causes	Unknown, possibly genetic
Risks	Family history of the condition
Diagnosis	Clinical diagnosis, X-ray
Differential diagnosis	Osteomyelitis, child abuse, scurvy
Prevention	N/A
Treatment	Supportive care, analgesics
Medication	Nonsteroidal anti-inflammatory drugs (NSAIDs)
Prognosis	Generally good, resolves with time
Frequency	Rare
Deaths	N/A

Infantile cortical hyperostosis is a rare, self-limited inflammatory disorder of infants that causes bone changes, soft tissue swelling and irritability. The disease may be present at birth or occur shortly thereafter. The cause is unknown.

Symptoms

The symptoms of infantile cortical hyperostosis may include the following:

• Irritability
• Fever
• Swelling of soft tissues
• Deformities of the jaw, shoulder, elbow, wrist, or other areas due to the underlying bone abnormalities

Causes

The exact cause of infantile cortical hyperostosis is unknown. Some researchers believe it may be related to a viral infection. Others believe it may be a genetic disorder.

Diagnosis

The diagnosis of infantile cortical hyperostosis is usually made based on the clinical symptoms and physical examination. Imaging studies such as X-rays or CT scans may be used to confirm the diagnosis.

Treatment

Treatment for infantile cortical hyperostosis is usually supportive, as the condition often resolves on its own. This may include pain management and physical therapy to maintain joint mobility and prevent contractures.

Prognosis

The prognosis for infantile cortical hyperostosis is generally good. Most children with the condition recover completely with no lasting effects. However, in severe cases, there may be permanent deformity or functional impairment.

See also

• Osteitis
• Hyperostosis
• Pediatrics

References

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