Adenovirus infection

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Adenovirus infection
Micrograph of adenovirus infection
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Fever, sore throat, conjunctivitis, gastroenteritis, respiratory illness
Complications Pneumonia, bronchiolitis, meningitis
Onset 2-14 days after exposure
Duration 1-2 weeks
Types N/A
Causes Adenovirus
Risks Immunocompromised, young children, crowded living conditions
Diagnosis PCR, viral culture, serology
Differential diagnosis Influenza, rhinovirus, respiratory syncytial virus
Prevention Hand washing, vaccination (for military personnel)
Treatment Supportive care, antiviral drugs (in severe cases)
Medication N/A
Prognosis Generally good, but can be severe in immunocompromised individuals
Frequency Common
Deaths N/A


A viral infection caused by adenoviruses



Adenovirus infection is a type of viral infection caused by adenoviruses, which are a group of common viruses that infect the lining of the eyes, airways and lungs, intestines, urinary tract, and nervous system. Adenovirus infections can cause a wide range of illnesses, from mild respiratory infections to severe diseases.

Virology[edit]

Adenoviruses are medium-sized, non-enveloped viruses with an icosahedral nucleocapsid containing a double-stranded DNA genome. They are classified into seven species (A to G) and include more than 50 serotypes that can infect humans. Adenoviruses are known for their ability to cause infections in various tissues and organs.

Transmission[edit]

Adenoviruses are highly contagious and can spread through:

  • Direct contact with an infected person
  • Respiratory droplets from coughs or sneezes
  • Contact with contaminated surfaces or objects
  • Fecal-oral route, particularly in settings with poor sanitation

Clinical Manifestations[edit]

Adenovirus infections can present with a variety of symptoms depending on the site of infection:

Respiratory Infections[edit]

Adenoviruses are a common cause of respiratory illnesses, especially in children. Symptoms may include:

Gastrointestinal Infections[edit]

Adenoviruses can cause gastroenteritis, particularly in young children, leading to:

  • Diarrhea
  • Vomiting
  • Abdominal pain

Ocular Infections[edit]

Adenoviruses can cause eye infections such as:

Other Infections[edit]

In rare cases, adenoviruses can cause:

Diagnosis[edit]

Diagnosis of adenovirus infection can be made through:

  • PCR testing
  • Viral culture
  • Antigen detection tests
  • Serology

Treatment[edit]

There is no specific antiviral treatment for adenovirus infections. Management is generally supportive and includes:

  • Rest
  • Hydration
  • Over-the-counter medications to relieve symptoms

In severe cases, particularly in immunocompromised patients, antiviral medications such as cidofovir may be considered.

Prevention[edit]

Preventive measures include:

  • Good hand hygiene
  • Avoiding close contact with infected individuals
  • Disinfection of contaminated surfaces
  • Vaccination for military personnel against certain adenovirus serotypes

Related pages[edit]

Gallery[edit]

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