Chaste

Software testing tool

Chaste (Cancer, Heart and Soft Tissue Environment) is an open-source software library developed by the University of Oxford. It is designed for computational modeling and simulation in the fields of cardiac electrophysiology, cancer biology, and soft tissue mechanics. Chaste is implemented in C++ and is available under the BSD license.

Overview

Chaste provides a flexible and extensible framework for conducting large-scale simulations. It is particularly focused on multiscale modeling, allowing researchers to integrate models at different biological scales, from the molecular level to the whole organ level. The software is designed to be highly modular, enabling users to customize and extend its functionality to suit their specific research needs.

Features

• Cardiac Electrophysiology: Chaste includes models for simulating the electrical activity of the heart, including action potential propagation and electrocardiogram (ECG) generation.
• Cancer Modeling: The software supports the simulation of tumor growth and the effects of various treatments, incorporating models of cell proliferation, migration, and interaction with the surrounding tissue.
• Soft Tissue Mechanics: Chaste can model the mechanical behavior of soft tissues, including the response to external forces and the interaction with other biological systems.

Applications

Chaste is used by researchers in various fields, including biomedical engineering, computational biology, and systems biology. It has been applied to study cardiac arrhythmias, optimize cancer treatment strategies, and investigate the mechanical properties of biological tissues.

Development and Community

The development of Chaste is led by a team at the University of Oxford, with contributions from researchers and developers worldwide. The project encourages community involvement and collaboration, providing extensive documentation and support for users.

See also

• Computational biology
• Biomedical engineering
• Systems biology
• Multiscale modeling
• Cardiac electrophysiology
• Cancer research
• Soft tissue mechanics

External links

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