Apudoma

Apudoma is a type of tumor that originates from the APUD cells (Amine Precursor Uptake and Decarboxylation cells). These cells are found throughout the body, particularly in the gastrointestinal tract and the respiratory system.

Overview

APUDomas are a group of rare tumors that can produce various hormones. They are often associated with specific syndromes due to the hormones they produce. The term "APUDoma" is derived from the system of cells from which these tumors originate, the APUD system.

Classification

APUDomas can be classified based on the type of APUD cell they originate from. Some of the most common types of APUDomas include:

• Carcinoid tumors
• Pancreatic neuroendocrine tumors
• Pheochromocytoma
• Medullary thyroid carcinoma
• Small cell lung cancer

Symptoms

The symptoms of APUDomas can vary greatly depending on the type of hormone the tumor is producing. Some common symptoms include:

• Diarrhea
• Flushing
• Wheezing
• High blood pressure
• Rapid heartbeat

Diagnosis

Diagnosis of APUDomas often involves a combination of imaging tests, blood tests, and urine tests. In some cases, a biopsy may be needed to confirm the diagnosis.

Treatment

Treatment for APUDomas depends on the type of tumor, its size, and its location. Treatment options may include surgery, radiation therapy, chemotherapy, or hormone therapy.

See Also

• Neuroendocrine tumor
• Endocrine system
• Oncology

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