7-Methyl-α-ethyltryptamine

Chemical compound

7-Methyl-α-ethyltryptamine
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CAS Number	178557-12-9
PubChem	44357064
DrugBank
ChemSpider	23272934
KEGG

7-Methyl-α-ethyltryptamine (also known as 7-Me-AET) is a psychedelic and entactogen of the tryptamine class. It is structurally related to α-ethyltryptamine (AET) and 7-methyltryptamine.

Chemical structure

Skeletal formula of 7-Methyl-α-ethyltryptamine

7-Methyl-α-ethyltryptamine is a derivative of tryptamine, which is a naturally occurring compound found in many plants and animals. The structure of 7-Me-AET includes a methyl group at the 7-position of the indole ring and an ethyl group at the alpha position of the side chain. This modification is believed to influence its pharmacological properties.

Pharmacology

The pharmacological effects of 7-Me-AET are not well-documented, but it is presumed to act as a serotonin receptor agonist, similar to other tryptamines. This action is thought to be responsible for its psychedelic and entactogenic effects. The compound may interact with various serotonin receptor subtypes, including the 5-HT2A receptor, which is commonly associated with the effects of psychedelics.

Effects

The effects of 7-Me-AET are largely anecdotal, as there is limited scientific research on this compound. Users have reported experiences similar to those of other tryptamines, including altered perception, mood enhancement, and increased empathy. The duration and intensity of these effects can vary depending on the dose and individual metabolism.

Legal status

The legal status of 7-Methyl-α-ethyltryptamine varies by country. In some jurisdictions, it may be considered a controlled substance due to its structural similarity to other regulated tryptamines. It is important for individuals to be aware of the legal implications of possessing or using this compound in their region.

Synthesis

The synthesis of 7-Me-AET involves the modification of the tryptamine backbone. This typically includes the introduction of a methyl group at the 7-position and an ethyl group at the alpha position. The specific synthetic route can vary, and detailed procedures are generally found in specialized chemical literature.

Related compounds

• α-Ethyltryptamine (AET)
• 7-Methyltryptamine
• N,N-Dimethyltryptamine (DMT)
• Psilocybin

See also

• List of tryptamines
• Psychedelic drug
• Entactogen

Related pages

• Tryptamine
• Serotonin receptor
• Psychedelic research