Cyclopentamine

Cyclopentamine is a sympathomimetic alkylamine, classified as a vasoconstrictor. Cyclopentamine acts as an agonist of the α- and β-adrenergic receptors.

History

Cyclopentamine was developed by the American pharmaceutical company Smith, Kline & French in the late 1940s as a replacement for ephedrine in their popular over-the-counter weight loss drug Eskatrol. The use of cyclopentamine in over-the-counter drugs was later banned by the Food and Drug Administration (FDA) due to its potential for abuse.

Pharmacology

Cyclopentamine is a sympathomimetic drug which increases the levels of norepinephrine, dopamine, and serotonin in the body. This can lead to a number of physiological effects, including increased heart rate and blood pressure, bronchodilation, and decreased appetite.

Side Effects

The side effects of cyclopentamine are similar to those of other sympathomimetic drugs. They can include hypertension, tachycardia, insomnia, and anxiety. In rare cases, cyclopentamine can also cause psychosis.

Legal Status

Cyclopentamine is currently a controlled substance in many countries, including the United States and the United Kingdom. It is classified as a Schedule III drug under the Controlled Substances Act in the United States.

See Also

• Amphetamine
• Methamphetamine
• Ephedrine

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