Fenoterol

A bronchodilator used in the treatment of asthma and other respiratory conditions

Fenoterol is a bronchodilator medication primarily used in the management of asthma and other conditions associated with bronchospasm. It is a selective beta-2 adrenergic receptor agonist that works by relaxing the muscles in the airways and increasing airflow to the lungs.

Mechanism of Action

Fenoterol acts on the beta-2 adrenergic receptors located in the smooth muscle of the airways. By stimulating these receptors, fenoterol causes relaxation of the bronchial muscles, leading to dilation of the airways. This action helps to relieve symptoms of bronchospasm such as wheezing, coughing, and shortness of breath.

Uses

Fenoterol is indicated for the relief and prevention of bronchospasm in patients with reversible obstructive airway disease, including:

• Asthma
• Chronic obstructive pulmonary disease (COPD)
• Exercise-induced bronchospasm

Administration

Fenoterol is commonly administered via inhalation, which allows for direct delivery to the lungs and rapid onset of action. It is available in various forms, including metered-dose inhalers and nebulizer solutions.

Side Effects

Common side effects of fenoterol include:

• Tremor
• Tachycardia
• Palpitations
• Nervousness
• Headache

Less common but more serious side effects can include:

• Hypokalemia
• Hyperglycemia
• Paradoxical bronchospasm

Precautions

Patients with cardiovascular disease, diabetes mellitus, or hyperthyroidism should use fenoterol with caution. It is important to monitor for signs of excessive use, which can lead to decreased effectiveness and increased side effects.

Interactions

Fenoterol may interact with other medications, including:

• Beta-blockers, which can reduce the effectiveness of fenoterol
• Diuretics, which can increase the risk of hypokalemia
• Monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants, which can enhance the cardiovascular effects of fenoterol

Images

A typical metered-dose inhaler used for administering fenoterol.

File:Bronchodilation.png

Diagram showing the mechanism of bronchodilation.

Related Pages

• Asthma
• Chronic obstructive pulmonary disease
• Beta-2 adrenergic receptor
• Bronchodilator