5-MeO-MET

A psychedelic compound

5-MeO-MET
File:5-MeO-MET.svg
INN
Drug class
Routes of administration	Oral, Insufflation
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status	Unscheduled
CAS Number	101717-60-0
PubChem	44349264
DrugBank
ChemSpider	23249924
KEGG

5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a psychedelic compound belonging to the tryptamine class. It is chemically related to other tryptamines such as 5-MeO-DMT and 5-MeO-DiPT.

Chemical structure and properties

5-MeO-MET is a synthetic compound with the chemical formula C₁₃H₁₈N₂O. It features a methoxy group at the 5-position of the indole ring, similar to other 5-methoxy tryptamines. The compound also includes an N-methyl-N-ethyl group attached to the ethylamine chain.

Pharmacology

5-MeO-MET acts as a serotonin receptor agonist, primarily affecting the 5-HT2A receptor. This action is believed to be responsible for its psychedelic effects. The compound's pharmacological profile is similar to other 5-methoxy tryptamines, though specific binding affinities and metabolic pathways have not been extensively studied.

Effects

The effects of 5-MeO-MET are reported to be similar to those of other psychedelic tryptamines, including altered perception, enhanced introspection, and changes in mood and cognition. Users have described visual and auditory hallucinations, as well as a sense of euphoria and spiritual experiences.

Dosage and administration

5-MeO-MET is typically administered orally or via insufflation. The dosage range is reported to be between 5 to 20 milligrams, with effects lasting approximately 4 to 6 hours. As with all psychedelics, the effects can vary significantly based on individual physiology, set, and setting.

Legal status

5-MeO-MET is not specifically scheduled under the Controlled Substances Act in the United States, but it may be considered an analogue of other controlled tryptamines, making it potentially subject to prosecution under the Federal Analogue Act. Its legal status varies internationally.

Safety and toxicity

There is limited data on the safety and toxicity of 5-MeO-MET. As with other psychedelics, there is a potential for psychological distress, particularly in individuals with a predisposition to mental health disorders. Users are advised to exercise caution and ensure a safe environment when using the compound.

Related pages

• Tryptamine
• Psychedelic drug
• 5-MeO-DMT
• Serotonin receptor