Tangeretin

Tangeretin is a polymethoxylated flavone, a type of flavonoid, that is found in citrus peels and in some herbs. It is most notably found in tangerines, from which it derives its name. Tangeretin has been studied for its potential health benefits, including its anti-inflammatory, anti-cancer, and neuroprotective properties.

Chemical Structure

Tangeretin is a polymethoxylated flavone, meaning it contains multiple methoxy groups attached to its flavone backbone. Its chemical formula is C20H20O7, and its systematic name is 4',5,6,7,8-Pentamethoxyflavone.

Sources

Tangeretin is found in the peels of citrus fruits, particularly tangerines, but also in oranges and grapefruits. It is also found in some herbs, such as Artemisia and Oregano.

Health Benefits

Anti-inflammatory Properties

Tangeretin has been shown to have anti-inflammatory properties. It inhibits the production of pro-inflammatory cytokines, which are proteins that promote inflammation.

Anti-cancer Properties

Tangeretin has been studied for its potential anti-cancer properties. It has been shown to inhibit the growth of various types of cancer cells, including breast, lung, and colon cancer cells.

Neuroprotective Properties

Tangeretin has also been studied for its potential neuroprotective properties. It has been shown to protect neurons from damage caused by oxidative stress, which is thought to play a role in neurodegenerative diseases like Alzheimer's disease and Parkinson's disease.

Safety and Side Effects

While tangeretin is generally considered safe, it can interact with certain medications, particularly those metabolized by the liver. It can also cause allergic reactions in some individuals.

See Also

• Flavonoids
• Citrus
• Anti-inflammatory
• Anti-cancer
• Neuroprotection

References

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