Pylephlebitis

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Pylephlebitis is a rare condition that involves thrombophlebitis of the portal vein, usually in the context of intra-abdominal infection or inflammation.

Definition

Pylephlebitis is a septic thrombophlebitis of the portal vein, typically secondary to an intra-abdominal infection. The condition is rare, but can be life-threatening if not treated promptly.

Causes

The most common cause of pylephlebitis is an infection in the abdomen, particularly diverticulitis and appendicitis. Other causes can include pancreatitis, inflammatory bowel disease, pelvic inflammatory disease, and cholecystitis.

Symptoms

Symptoms of pylephlebitis can vary, but often include fever, abdominal pain, and jaundice. Other symptoms can include nausea, vomiting, and diarrhea.

Diagnosis

Diagnosis of pylephlebitis often involves a combination of medical history, physical examination, and imaging studies. Computed tomography (CT) is the most commonly used imaging study for diagnosing pylephlebitis.

Treatment

Treatment for pylephlebitis typically involves antibiotics to treat the underlying infection, and anticoagulation therapy to prevent the formation of new clots. In some cases, surgical intervention may be necessary.

Prognosis

The prognosis for pylephlebitis is generally good with prompt and appropriate treatment. However, if left untreated, the condition can be life-threatening.

See also

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