FibroTest

FibroTest is a biomarker assay that is used to measure the degree of liver fibrosis in patients. It is a non-invasive test that is often used as an alternative to liver biopsy. The test uses a combination of six serum markers to calculate a score that indicates the level of fibrosis. These markers include alpha-2-macroglobulin, haptoglobin, apolipoprotein A1, bilirubin, gamma-glutamyl transpeptidase (GGT), and alanine aminotransferase (ALT).

Overview

FibroTest is a diagnostic tool that is used to assess the level of liver fibrosis in patients. It is a non-invasive test that is often used as an alternative to liver biopsy, which can be invasive and carry risks. The test uses a combination of six serum markers to calculate a score that indicates the level of fibrosis. These markers include alpha-2-macroglobulin, haptoglobin, apolipoprotein A1, bilirubin, gamma-glutamyl transpeptidase (GGT), and alanine aminotransferase (ALT).

Methodology

The FibroTest uses a patented algorithm to calculate a score based on the levels of six serum markers. The score ranges from 0.00 to 1.00, with higher scores indicating a higher degree of fibrosis. The test is often used in conjunction with other diagnostic tools, such as imaging studies and clinical evaluation, to provide a comprehensive assessment of liver health.

Clinical Use

FibroTest is used in the clinical setting to assess the level of liver fibrosis in patients with chronic liver diseases, such as hepatitis C, hepatitis B, alcoholic liver disease, and non-alcoholic fatty liver disease. It is also used to monitor the progression of these diseases and the effectiveness of treatment.

Limitations

While the FibroTest is a valuable tool in the assessment of liver fibrosis, it is not without limitations. The test may not be accurate in patients with acute inflammation, Gilbert's syndrome, or extrahepatic cholestasis. Additionally, the test may not be able to differentiate between different stages of fibrosis.

See Also

• Liver fibrosis
• Liver biopsy
• Hepatitis C
• Hepatitis B
• Alcoholic liver disease
• Non-alcoholic fatty liver disease

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