Cocaine dependence
Cocaine dependence is a type of substance dependence that involves a psychological desire to use cocaine regularly. Cocaine is a powerful stimulant drug that increases levels of dopamine, a neurotransmitter associated with pleasure and reward, in the brain.
Causes
Cocaine dependence can develop after the repeated use of cocaine. This is due to the intense and immediate high that the drug produces, which can lead to repeated use and eventually dependence. Factors that can contribute to cocaine dependence include genetic predisposition, environmental factors, and the pharmacological effects of the drug.
Symptoms
Symptoms of cocaine dependence can include a strong desire or compulsion to use cocaine, difficulties in controlling cocaine use, a physiological withdrawal state, tolerance, and neglect of alternative pleasures or interests because of cocaine use.
Treatment
Treatment for cocaine dependence often involves a combination of psychotherapy, medication, and support groups. Cognitive behavioral therapy (CBT) is one of the most effective treatments for cocaine dependence. Medications such as Disulfiram and Modafinil have also been used to treat cocaine dependence.
See also
- Substance dependence
- Cocaine
- Stimulant
- Dopamine
- Genetics
- Psychotherapy
- Cognitive behavioral therapy
- Disulfiram
- Modafinil

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Cocaine dependence
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Graph showing past-year cocaine use from 2002 to 2019.
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