Autoimmune oophoritis

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Field	Gynecology
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Autoimmune oophoritis is a rare autoimmune disease where the body's immune system mistakenly attacks the ovaries.<ref>,

 The autoimmune diseases, 
 4th edition, 
 St. Louis, MO:Elsevier Academic Press, 
  
  
  
 ISBN 978-0-12-595961-2,</ref> This causes the ovaries to have inflammation, atrophy and fibrosis. The changes to the ovaries can cause them to not function properly.

Signs and symptoms

• Primary amenorrhea – where menstruation has never occurred
• Secondary amenorrhea – where menstruation occurred once puberty happened but then later stopped
• Infertility
• Sex hormone deficiency
• Lower abdominal pain
• Fever
• Malaise
• Vaginal discharge
• Irregular bleeding or absent menstrual period – also known as amenorrhea
• Symptoms that are related to cysts

Causes

The underlying cause of autoimmune oophoritis is unknown. In many cases it can be a part of lupus, pernicious anemia, myasthenia gravis, or other autoimmune conditions. Autoimmune oophoritis can be associated with autoimmune polyglandular syndrome type I and type II.<ref name=":0">

Autoimmune oophoritis(link). NIH.gov.

Accessed 2018-08-07.

</ref>

Diagnoses

Diagnosis involves a special blood test which looks for anti-steroid or anti-ovarian antibodies, a pelvic ultrasound to look for enlarged cystic ovaries, and other type of tests to rule out other issues that can be a part of primary ovarian insufficiency (POI).<ref name=":0" />

References

 This article incorporates public domain material from websites or documents of the National Institutes of Health.

External links

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