Benzylone

Benzylone is a psychoactive drug and research chemical of the cathinone class that has been sold online as a designer drug. It is a higher homologue of methylenedioxypyrovalerone (MDPV) and the p-methyl derivative of MDPHP.

Chemistry

Benzylone is a synthetic cathinone. Synthetic cathinones are derivatives of the naturally occurring amphetamine-like compound cathinone, which is found in the khat plant. Benzylone contains a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain. It is further substituted at R3 with a benzyl group. R4 of its phenyl ring is substituted with an additional methyl group.

Pharmacology

The pharmacology of benzylone is not well-studied. However, it is known to act as a norepinephrine-dopamine reuptake inhibitor (NDRI). It is believed to work by inhibiting the reuptake of the neurotransmitters norepinephrine and dopamine, increasing their concentration in the synaptic cleft and leading to increased neuronal activity.

Effects

The effects of benzylone can vary greatly depending on the dose, individual physiology, and method of administration. Common effects reported by users include stimulation, euphoria, increased alertness and focus, and increased sociability. However, negative side effects can include anxiety, paranoia, insomnia, and tachycardia.

Legal Status

The legal status of benzylone varies by country. In many jurisdictions, it is classified as a controlled substance due to its structural similarity to other banned synthetic cathinones.

See Also

• Cathinone
• Synthetic Cathinones
• Psychoactive Drug
• Research Chemical

References

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