Metynodiol diacetate
Metynodiol diacetate is a progestin medication which is used in hormone therapy. It is a derivative of progesterone and was introduced for medical use in the 1960s. Metynodiol diacetate is taken by mouth.
Pharmacology
Metynodiol diacetate is a progestogen, or an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has weak androgenic and estrogenic activity and no other important hormonal activity. The medication is a prodrug of noretynodrel, which is also a progestin.
Medical uses
Metynodiol diacetate is used as a component of menopausal hormone therapy to prevent endometrial hyperplasia and uterine cancer in women who are taking estrogens. It is also used in the treatment of gynecological disorders.
Side effects
Side effects of metynodiol diacetate include menstrual irregularities, nausea, breast tenderness, headache, and acne. It can also cause weight gain and mood changes.
History
Metynodiol diacetate was introduced for medical use in the 1960s. It is marketed widely throughout the world.
Society and culture
Metynodiol diacetate is marketed under a variety of brand names including Demulen, Cyclessa, and others.
See also
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