KiSS1-derived peptide receptor
KiSS1-derived peptide receptor (also known as GPR54 or KISS1R) is a G protein-coupled receptor that in humans is encoded by the KISS1R gene. It is a key player in the regulation of puberty and sexual maturation.
Function
The KiSS1-derived peptide receptor is a G protein-coupled receptor that binds to a family of peptides known as kisspeptins, which are derived from the KiSS1 gene. The interaction between kisspeptins and their receptor plays a crucial role in the regulation of the hypothalamic-pituitary-gonadal axis, which controls sexual maturation and reproductive function.
Clinical significance
Mutations in the KISS1R gene can lead to hypogonadotropic hypogonadism, a condition characterized by delayed or absent puberty and infertility. In addition, the KiSS1-derived peptide receptor has been implicated in the regulation of metastasis in various types of cancer, including breast cancer and melanoma.
See also
- Kisspeptin
- G protein-coupled receptor
- Hypothalamic-pituitary-gonadal axis
- Hypogonadotropic hypogonadism
References
Ad. Transform your health with W8MD Weight Loss, Sleep & MedSpa
Tired of being overweight?
Special offer:
Budget GLP-1 weight loss medications
- Semaglutide starting from $29.99/week and up with insurance for visit of $59.99 and up per week self pay.
- Tirzepatide starting from $45.00/week and up (dose dependent) or $69.99/week and up self pay
✔ Same-week appointments, evenings & weekends
Learn more:
- GLP-1 weight loss clinic NYC
- W8MD's NYC medical weight loss
- W8MD Philadelphia GLP-1 shots
- Philadelphia GLP-1 injections
- Affordable GLP-1 shots NYC
|
WikiMD Medical Encyclopedia |
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
