Transcriptome

Transcriptome refers to the complete set of RNA molecules, including mRNA, rRNA, tRNA, and other non-coding RNA produced by the genome under specific circumstances or in a specific cell using the process of transcription. The term "transcriptome" can also be used to describe the array of all mRNA molecules, or "transcripts", produced in one or a population of cells. The transcriptome of a cell is dynamic, changing in response to environmental conditions or other external stimuli.

Overview

The transcriptome can be seen as a subset of the proteome, that is, the entire set of proteins expressed by a genome. However, not all transcripts are translated into proteins. Non-coding RNAs have roles in regulating gene expression, and some are not translated into protein. The study of transcriptomics, also known as transcriptomics, involves the exploration of the transcriptome, often using high-throughput techniques such as microarray analysis.

Transcriptomics

Transcriptomics technologies are the techniques used to study an organism’s transcriptome, the sum of all of its RNA transcripts. The information content of an organism is recorded in the DNA of its genome and expressed through transcription. Here, mRNA serves as a transient intermediary molecule in the information network, whilst non-coding RNAs perform additional diverse functions. A transcriptome captures a snapshot in time of the total transcripts present in a cell.

See also

• Genome
• Proteome
• Metabolome
• Interactome

References

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