Placenta accreta spectrum
A spectrum of conditions involving abnormal placental attachment
Overview

The placenta accreta spectrum (PAS) refers to a range of conditions characterized by abnormal attachment of the placenta to the uterine wall. This spectrum includes placenta accreta, placenta increta, and placenta percreta, each defined by the depth of placental invasion into the uterine tissues.
Types of Placenta Accreta Spectrum
Placenta Accreta
In placenta accreta, the placenta attaches too deeply into the uterine wall but does not penetrate the myometrium. This is the most common form of PAS and can lead to complications during childbirth, particularly during the third stage of labor when the placenta is delivered.
Placenta Increta
Placenta increta occurs when the placenta invades the myometrium more deeply than in placenta accreta. This condition poses a higher risk of postpartum hemorrhage and may require surgical intervention to manage.
Placenta Percreta
The most severe form of PAS is placenta percreta, where the placenta penetrates through the entire uterine wall and may invade adjacent organs, such as the bladder. This condition often necessitates a hysterectomy to control bleeding and prevent further complications.
Risk Factors
Several factors increase the risk of developing PAS, including:
- Previous cesarean section
- Placenta previa
- Advanced maternal age
- Previous uterine surgery
- Multiparity
Diagnosis
PAS is typically diagnosed through ultrasound imaging, which can reveal abnormal placental attachment. In some cases, magnetic resonance imaging (MRI) may be used to assess the extent of placental invasion.
Management
Management of PAS requires a multidisciplinary approach involving obstetricians, anesthesiologists, and surgeons. Delivery is often planned via cesarean section in a controlled setting to minimize risks. In severe cases, a hysterectomy may be necessary to prevent life-threatening hemorrhage.
Prognosis
The prognosis for PAS varies depending on the severity of the condition and the promptness of treatment. With appropriate management, many women can have successful outcomes, although the risk of complications remains significant.
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