Ganglioneuroma: Difference between revisions

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{{SI}}
{{Infobox medical condition
| name            = Ganglioneuroma
| image          = [[File:Ganglioneuroma_CT_scan.jpg|250px]]
| caption        = CT scan showing a ganglioneuroma
| field          = [[Oncology]], [[Neurology]]
| symptoms        = Often asymptomatic, may cause [[pain]], [[neurological deficits]]
| complications  = [[Compression of adjacent structures]], [[hormonal imbalances]]
| onset          = Typically in [[childhood]] or [[young adulthood]]
| duration        = [[Chronic (medicine)|Chronic]]
| causes          = [[Neural crest]] cell origin
| risks          = [[Neurofibromatosis type I]], [[Multiple endocrine neoplasia]]
| diagnosis      = [[Imaging studies]], [[biopsy]]
| differential    = [[Neuroblastoma]], [[Ganglioneuroblastoma]], [[Schwannoma]]
| treatment      = [[Surgical resection]]
| prognosis      = Generally [[benign]]
| frequency      = Rare
}}
[[File:Ganglioneuroma_-_high_mag.jpg|High magnification of ganglioneuroma|thumb|left]]
[[File:Adrenal_ganglioneuroma_02.JPG|Adrenal ganglioneuroma|thumb|left]]
'''Ganglioneuroma''' is a rare, benign [[neoplasm]] that originates from the [[ganglion cells]] of the [[autonomic nervous system]]. It is most commonly found in the [[adrenal gland]], [[retroperitoneum]], and [[posterior mediastinum]].  
'''Ganglioneuroma''' is a rare, benign [[neoplasm]] that originates from the [[ganglion cells]] of the [[autonomic nervous system]]. It is most commonly found in the [[adrenal gland]], [[retroperitoneum]], and [[posterior mediastinum]].  
== Signs and Symptoms ==
== Signs and Symptoms ==
The symptoms of ganglioneuroma can vary greatly depending on the location of the tumor. Some patients may be asymptomatic, while others may experience symptoms such as [[abdominal pain]], [[hypertension]], and [[diarrhea]]. In some cases, the tumor may cause [[hormonal imbalance]] leading to symptoms such as [[excessive sweating]], [[rapid heart rate]], and [[high blood pressure]].
The symptoms of ganglioneuroma can vary greatly depending on the location of the tumor. Some patients may be asymptomatic, while others may experience symptoms such as [[abdominal pain]], [[hypertension]], and [[diarrhea]]. In some cases, the tumor may cause [[hormonal imbalance]] leading to symptoms such as [[excessive sweating]], [[rapid heart rate]], and [[high blood pressure]].
== Diagnosis ==
== Diagnosis ==
The diagnosis of ganglioneuroma is often made incidentally during imaging studies for unrelated conditions. However, if a ganglioneuroma is suspected, a combination of [[imaging studies]], [[laboratory tests]], and [[biopsy]] may be used to confirm the diagnosis. Imaging studies such as [[CT scan]] and [[MRI]] can help identify the location and size of the tumor. Laboratory tests can help identify any hormonal imbalances caused by the tumor. A biopsy, where a small sample of the tumor is removed for examination under a microscope, can confirm the diagnosis.
The diagnosis of ganglioneuroma is often made incidentally during imaging studies for unrelated conditions. However, if a ganglioneuroma is suspected, a combination of [[imaging studies]], [[laboratory tests]], and [[biopsy]] may be used to confirm the diagnosis. Imaging studies such as [[CT scan]] and [[MRI]] can help identify the location and size of the tumor. Laboratory tests can help identify any hormonal imbalances caused by the tumor. A biopsy, where a small sample of the tumor is removed for examination under a microscope, can confirm the diagnosis.
== Treatment ==
== Treatment ==
The treatment for ganglioneuroma typically involves surgical removal of the tumor. In some cases, if the tumor is small and not causing any symptoms, a watchful waiting approach may be taken. However, if the tumor is large, causing symptoms, or growing, surgical removal is usually recommended. In some cases, [[chemotherapy]] or [[radiation therapy]] may be used in addition to surgery.
The treatment for ganglioneuroma typically involves surgical removal of the tumor. In some cases, if the tumor is small and not causing any symptoms, a watchful waiting approach may be taken. However, if the tumor is large, causing symptoms, or growing, surgical removal is usually recommended. In some cases, [[chemotherapy]] or [[radiation therapy]] may be used in addition to surgery.
== Prognosis ==
== Prognosis ==
The prognosis for ganglioneuroma is generally good, as the tumor is benign and does not typically spread to other parts of the body. However, the prognosis can vary depending on the size and location of the tumor, as well as the patient's overall health.
The prognosis for ganglioneuroma is generally good, as the tumor is benign and does not typically spread to other parts of the body. However, the prognosis can vary depending on the size and location of the tumor, as well as the patient's overall health.
== See Also ==
== See Also ==
* [[Neoplasm]]
* [[Neoplasm]]
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* [[Chemotherapy]]
* [[Chemotherapy]]
* [[Radiation therapy]]
* [[Radiation therapy]]
[[Category:Medical conditions]]
[[Category:Medical conditions]]
[[Category:Neoplasms]]
[[Category:Neoplasms]]
[[Category:Nervous system disorders]]
[[Category:Nervous system disorders]]
{{stub}}
{{stub}}
<gallery>
File:Ganglioneuroma_CT_scan.jpg|CT scan of a ganglioneuroma
File:Ganglioneuroma_-_high_mag.jpg|High magnification of ganglioneuroma
File:Adrenal_ganglioneuroma_02.JPG|Adrenal ganglioneuroma
</gallery>

Latest revision as of 21:20, 9 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Ganglioneuroma
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Often asymptomatic, may cause pain, neurological deficits
Complications Compression of adjacent structures, hormonal imbalances
Onset Typically in childhood or young adulthood
Duration Chronic
Types N/A
Causes Neural crest cell origin
Risks Neurofibromatosis type I, Multiple endocrine neoplasia
Diagnosis Imaging studies, biopsy
Differential diagnosis Neuroblastoma, Ganglioneuroblastoma, Schwannoma
Prevention N/A
Treatment Surgical resection
Medication N/A
Prognosis Generally benign
Frequency Rare
Deaths N/A


High magnification of ganglioneuroma
Adrenal ganglioneuroma

Ganglioneuroma is a rare, benign neoplasm that originates from the ganglion cells of the autonomic nervous system. It is most commonly found in the adrenal gland, retroperitoneum, and posterior mediastinum.

Signs and Symptoms[edit]

The symptoms of ganglioneuroma can vary greatly depending on the location of the tumor. Some patients may be asymptomatic, while others may experience symptoms such as abdominal pain, hypertension, and diarrhea. In some cases, the tumor may cause hormonal imbalance leading to symptoms such as excessive sweating, rapid heart rate, and high blood pressure.

Diagnosis[edit]

The diagnosis of ganglioneuroma is often made incidentally during imaging studies for unrelated conditions. However, if a ganglioneuroma is suspected, a combination of imaging studies, laboratory tests, and biopsy may be used to confirm the diagnosis. Imaging studies such as CT scan and MRI can help identify the location and size of the tumor. Laboratory tests can help identify any hormonal imbalances caused by the tumor. A biopsy, where a small sample of the tumor is removed for examination under a microscope, can confirm the diagnosis.

Treatment[edit]

The treatment for ganglioneuroma typically involves surgical removal of the tumor. In some cases, if the tumor is small and not causing any symptoms, a watchful waiting approach may be taken. However, if the tumor is large, causing symptoms, or growing, surgical removal is usually recommended. In some cases, chemotherapy or radiation therapy may be used in addition to surgery.

Prognosis[edit]

The prognosis for ganglioneuroma is generally good, as the tumor is benign and does not typically spread to other parts of the body. However, the prognosis can vary depending on the size and location of the tumor, as well as the patient's overall health.

See Also[edit]

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