Necrobiosis lipoidica: Difference between revisions
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'''Necrobiosis Lipoidica''' is a rare chronic skin condition, typically manifesting as shiny, firm, raised skin patches. It is often associated with [[diabetes mellitus]], although the exact cause remains unknown. | {{SI}} | ||
{{Infobox medical condition | |||
| name = Necrobiosis lipoidica | |||
| image = [[File:Necrobiosislipoidica.jpg|alt=Necrobiosis lipoidica|upright=1.15]] | |||
| caption = Necrobiosis lipoidica on the lower leg | |||
| synonyms = Necrobiosis lipoidica diabeticorum | |||
| specialty = [[Dermatology]] | |||
| symptoms = [[Skin]] lesions, [[ulcer (dermatology)|ulceration]] | |||
| complications = [[Infection]], [[scarring]] | |||
| onset = Typically in [[adulthood]] | |||
| duration = [[Chronic (medicine)|Chronic]] | |||
| causes = Unknown, possibly related to [[diabetes mellitus]] | |||
| risks = [[Diabetes]], [[female]] gender | |||
| diagnosis = [[Clinical diagnosis]], [[skin biopsy]] | |||
| differential = [[Granuloma annulare]], [[rheumatoid nodule]], [[sarcoidosis]] | |||
| treatment = [[Topical corticosteroids]], [[intralesional steroid injection]], [[phototherapy]] | |||
| medication = [[Corticosteroids]], [[immunosuppressive drugs]] | |||
| frequency = Rare | |||
}} | |||
[[File:Necrobiosis_lipoidica_-_low_mag.jpg|Necrobiosis lipoidica - low magnification|thumb|left]] | |||
'''Necrobiosis Lipoidica''' is a rare chronic skin condition, typically manifesting as shiny, firm, raised skin patches. It is often associated with [[diabetes mellitus]], although the exact cause remains unknown. | |||
== Signs and Symptoms == | == Signs and Symptoms == | ||
Necrobiosis Lipoidica typically presents as shiny, firm, raised patches on the skin. These patches are often yellowish or reddish-brown in color, and may be surrounded by a thin, pale border. The skin in these areas may be thin and easily damaged, leading to the formation of ulcers. | Necrobiosis Lipoidica typically presents as shiny, firm, raised patches on the skin. These patches are often yellowish or reddish-brown in color, and may be surrounded by a thin, pale border. The skin in these areas may be thin and easily damaged, leading to the formation of ulcers. | ||
== Causes == | == Causes == | ||
The exact cause of Necrobiosis Lipoidica is unknown. However, it is often associated with [[diabetes mellitus]], and is more common in individuals with this condition. Other potential risk factors include trauma, inflammation, and certain autoimmune diseases. | The exact cause of Necrobiosis Lipoidica is unknown. However, it is often associated with [[diabetes mellitus]], and is more common in individuals with this condition. Other potential risk factors include trauma, inflammation, and certain autoimmune diseases. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of Necrobiosis Lipoidica is typically based on the appearance of the skin lesions. A skin biopsy may be performed to confirm the diagnosis and rule out other conditions. | Diagnosis of Necrobiosis Lipoidica is typically based on the appearance of the skin lesions. A skin biopsy may be performed to confirm the diagnosis and rule out other conditions. | ||
== Treatment == | == Treatment == | ||
Treatment for Necrobiosis Lipoidica is aimed at managing symptoms and preventing complications. This may include the use of topical or injectable corticosteroids, laser therapy, or surgery in severe cases. | Treatment for Necrobiosis Lipoidica is aimed at managing symptoms and preventing complications. This may include the use of topical or injectable corticosteroids, laser therapy, or surgery in severe cases. | ||
== Prognosis == | == Prognosis == | ||
The prognosis for individuals with Necrobiosis Lipoidica is generally good, although the condition can cause significant cosmetic concerns and potential complications such as ulceration and infection. | The prognosis for individuals with Necrobiosis Lipoidica is generally good, although the condition can cause significant cosmetic concerns and potential complications such as ulceration and infection. | ||
== See Also == | == See Also == | ||
* [[Diabetes mellitus]] | * [[Diabetes mellitus]] | ||
* [[Skin biopsy]] | * [[Skin biopsy]] | ||
* [[Corticosteroids]] | * [[Corticosteroids]] | ||
[[Category:Skin conditions]] | [[Category:Skin conditions]] | ||
[[Category:Diabetes]] | [[Category:Diabetes]] | ||
{{stub}} | {{stub}} | ||
== References == | == References == | ||
<references /> | <references /> | ||
== External Links == | == External Links == | ||
* [https://www.mayoclinic.org/diseases-conditions/necrobiosis-lipoidica/cdc-20384952 Mayo Clinic - Necrobiosis Lipoidica] | * [https://www.mayoclinic.org/diseases-conditions/necrobiosis-lipoidica/cdc-20384952 Mayo Clinic - Necrobiosis Lipoidica] | ||
* [https://www.dermnetnz.org/topics/necrobiosis-lipoidica DermNet NZ - Necrobiosis Lipoidica] | * [https://www.dermnetnz.org/topics/necrobiosis-lipoidica DermNet NZ - Necrobiosis Lipoidica] | ||
{{DEFAULTSORT:Necrobiosis Lipoidica}} | {{DEFAULTSORT:Necrobiosis Lipoidica}} | ||
Latest revision as of 05:49, 9 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Necrobiosis lipoidica | |
|---|---|
| |
| Synonyms | Necrobiosis lipoidica diabeticorum |
| Pronounce | N/A |
| Specialty | Dermatology |
| Symptoms | Skin lesions, ulceration |
| Complications | Infection, scarring |
| Onset | Typically in adulthood |
| Duration | Chronic |
| Types | N/A |
| Causes | Unknown, possibly related to diabetes mellitus |
| Risks | Diabetes, female gender |
| Diagnosis | Clinical diagnosis, skin biopsy |
| Differential diagnosis | Granuloma annulare, rheumatoid nodule, sarcoidosis |
| Prevention | N/A |
| Treatment | Topical corticosteroids, intralesional steroid injection, phototherapy |
| Medication | Corticosteroids, immunosuppressive drugs |
| Prognosis | N/A |
| Frequency | Rare |
| Deaths | N/A |
Necrobiosis Lipoidica is a rare chronic skin condition, typically manifesting as shiny, firm, raised skin patches. It is often associated with diabetes mellitus, although the exact cause remains unknown.
Signs and Symptoms[edit]
Necrobiosis Lipoidica typically presents as shiny, firm, raised patches on the skin. These patches are often yellowish or reddish-brown in color, and may be surrounded by a thin, pale border. The skin in these areas may be thin and easily damaged, leading to the formation of ulcers.
Causes[edit]
The exact cause of Necrobiosis Lipoidica is unknown. However, it is often associated with diabetes mellitus, and is more common in individuals with this condition. Other potential risk factors include trauma, inflammation, and certain autoimmune diseases.
Diagnosis[edit]
Diagnosis of Necrobiosis Lipoidica is typically based on the appearance of the skin lesions. A skin biopsy may be performed to confirm the diagnosis and rule out other conditions.
Treatment[edit]
Treatment for Necrobiosis Lipoidica is aimed at managing symptoms and preventing complications. This may include the use of topical or injectable corticosteroids, laser therapy, or surgery in severe cases.
Prognosis[edit]
The prognosis for individuals with Necrobiosis Lipoidica is generally good, although the condition can cause significant cosmetic concerns and potential complications such as ulceration and infection.
