Latent autoimmune diabetes in adults: Difference between revisions
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{{Infobox medical condition | |||
| name = Latent autoimmune diabetes in adults | |||
| image = [[File:Blue_circle_for_diabetes.svg|alt=Blue circle for diabetes|upright=0.75]] | |||
| caption = The blue circle is the international symbol for diabetes. | |||
| synonyms = LADA, [[Type 1.5 diabetes]] | |||
| pronounce = | |||
| specialty = [[Endocrinology]] | |||
| symptoms = [[Hyperglycemia]], [[weight loss]], [[fatigue]], [[polyuria]], [[polydipsia]] | |||
| onset = Typically in [[adulthood]] | |||
| duration = [[Chronic (medicine)|Chronic]] | |||
| causes = [[Autoimmune disease]] | |||
| risks = [[Genetic predisposition]], [[environmental factors]] | |||
| diagnosis = [[Blood test]] for [[autoantibodies]], [[C-peptide]] levels | |||
| differential = [[Type 1 diabetes]], [[Type 2 diabetes]] | |||
| treatment = [[Insulin therapy]], [[dietary management]], [[exercise]] | |||
| medication = [[Insulin]] | |||
| prognosis = Progressive loss of [[beta cell]] function | |||
| frequency = 5-10% of [[diabetes mellitus]] cases in adults | |||
}} | |||
[[File:PDB GAD67.jpg|Latent autoimmune diabetes in adults|thumb|left]] | |||
'''Latent autoimmune diabetes in adults''' ('''LADA''') is a form of [[diabetes mellitus type 1]] that occurs in adulthood, often with a slower course of onset than type 1 diabetes diagnosed in juveniles. | '''Latent autoimmune diabetes in adults''' ('''LADA''') is a form of [[diabetes mellitus type 1]] that occurs in adulthood, often with a slower course of onset than type 1 diabetes diagnosed in juveniles. | ||
== Introduction == | |||
== | |||
LADA is a form of [[Type 1 diabetes]] that is diagnosed in individuals who are older than the typical age of onset of type 1 diabetes. This form of diabetes is characterized by the presence of similar autoantibodies to those found in type 1 diabetes, but with a slower progression of [[beta cell]] destruction. This results in a form of type 1 diabetes that may initially be mistaken for [[Type 2 diabetes]]. | LADA is a form of [[Type 1 diabetes]] that is diagnosed in individuals who are older than the typical age of onset of type 1 diabetes. This form of diabetes is characterized by the presence of similar autoantibodies to those found in type 1 diabetes, but with a slower progression of [[beta cell]] destruction. This results in a form of type 1 diabetes that may initially be mistaken for [[Type 2 diabetes]]. | ||
==Symptoms== | ==Symptoms== | ||
The symptoms of LADA are similar to those of other forms of diabetes, including frequent urination, excessive thirst, weight loss, and fatigue. However, because the onset of LADA is slower than that of juvenile type 1 diabetes, these symptoms may be less severe or noticeable at first. | The symptoms of LADA are similar to those of other forms of diabetes, including frequent urination, excessive thirst, weight loss, and fatigue. However, because the onset of LADA is slower than that of juvenile type 1 diabetes, these symptoms may be less severe or noticeable at first. | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of LADA is typically made through a combination of clinical evaluation and laboratory testing. The presence of autoantibodies against [[glutamic acid decarboxylase]] (GAD) is a key marker for LADA. | Diagnosis of LADA is typically made through a combination of clinical evaluation and laboratory testing. The presence of autoantibodies against [[glutamic acid decarboxylase]] (GAD) is a key marker for LADA. | ||
==Treatment== | ==Treatment== | ||
Treatment for LADA typically involves the use of insulin, similar to the treatment for type 1 diabetes. However, because the destruction of beta cells is slower in LADA, some individuals may initially be able to manage their blood glucose levels with lifestyle changes or oral medications. | Treatment for LADA typically involves the use of insulin, similar to the treatment for type 1 diabetes. However, because the destruction of beta cells is slower in LADA, some individuals may initially be able to manage their blood glucose levels with lifestyle changes or oral medications. | ||
==See also== | ==See also== | ||
* [[Diabetes mellitus type 1]] | * [[Diabetes mellitus type 1]] | ||
| Line 18: | Line 34: | ||
* [[Autoimmune disease]] | * [[Autoimmune disease]] | ||
* [[Glutamic acid decarboxylase]] | * [[Glutamic acid decarboxylase]] | ||
[[Category:Diabetes]] | [[Category:Diabetes]] | ||
[[Category:Autoimmune diseases]] | [[Category:Autoimmune diseases]] | ||
[[Category:Endocrine diseases]] | [[Category:Endocrine diseases]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 04:04, 9 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Latent autoimmune diabetes in adults | |
|---|---|
| |
| Synonyms | LADA, Type 1.5 diabetes |
| Pronounce | |
| Specialty | Endocrinology |
| Symptoms | Hyperglycemia, weight loss, fatigue, polyuria, polydipsia |
| Complications | N/A |
| Onset | Typically in adulthood |
| Duration | Chronic |
| Types | N/A |
| Causes | Autoimmune disease |
| Risks | Genetic predisposition, environmental factors |
| Diagnosis | Blood test for autoantibodies, C-peptide levels |
| Differential diagnosis | Type 1 diabetes, Type 2 diabetes |
| Prevention | N/A |
| Treatment | Insulin therapy, dietary management, exercise |
| Medication | Insulin |
| Prognosis | Progressive loss of beta cell function |
| Frequency | 5-10% of diabetes mellitus cases in adults |
| Deaths | N/A |
Latent autoimmune diabetes in adults (LADA) is a form of diabetes mellitus type 1 that occurs in adulthood, often with a slower course of onset than type 1 diabetes diagnosed in juveniles.
Introduction[edit]
LADA is a form of Type 1 diabetes that is diagnosed in individuals who are older than the typical age of onset of type 1 diabetes. This form of diabetes is characterized by the presence of similar autoantibodies to those found in type 1 diabetes, but with a slower progression of beta cell destruction. This results in a form of type 1 diabetes that may initially be mistaken for Type 2 diabetes.
Symptoms[edit]
The symptoms of LADA are similar to those of other forms of diabetes, including frequent urination, excessive thirst, weight loss, and fatigue. However, because the onset of LADA is slower than that of juvenile type 1 diabetes, these symptoms may be less severe or noticeable at first.
Diagnosis[edit]
Diagnosis of LADA is typically made through a combination of clinical evaluation and laboratory testing. The presence of autoantibodies against glutamic acid decarboxylase (GAD) is a key marker for LADA.
Treatment[edit]
Treatment for LADA typically involves the use of insulin, similar to the treatment for type 1 diabetes. However, because the destruction of beta cells is slower in LADA, some individuals may initially be able to manage their blood glucose levels with lifestyle changes or oral medications.
