Paraganglioma: Difference between revisions
mNo edit summary |
CSV import |
||
| Line 1: | Line 1: | ||
{{SI}} | |||
{{Infobox medical condition | |||
| name = Paraganglioma | |||
| image = [[File:Carotid_body_tumour_2_intermed_mag.jpg|alt=Micrograph of a paraganglioma]] | |||
| caption = Micrograph of a paraganglioma | |||
| field = [[Oncology]] | |||
| synonyms = Glomus tumor, chemodectoma | |||
| symptoms = [[Hypertension]], [[headache]], [[palpitations]], [[sweating]], [[anxiety]] | |||
| complications = [[Metastasis]], [[pheochromocytoma]] | |||
| onset = Typically in [[adulthood]] | |||
| duration = Variable | |||
| types = [[Carotid body tumor]], [[glomus jugulare]], [[glomus tympanicum]], [[glomus vagale]] | |||
| causes = Genetic mutations (e.g., [[SDHB]], [[SDHD]]) | |||
| risks = Family history, certain genetic syndromes | |||
| diagnosis = [[Imaging studies]], [[biopsy]] | |||
| differential = [[Pheochromocytoma]], [[schwannoma]], [[neurofibroma]] | |||
| prevention = Genetic counseling for at-risk individuals | |||
| treatment = [[Surgery]], [[radiation therapy]], [[chemotherapy]] | |||
| medication = [[Alpha blockers]], [[beta blockers]] | |||
| prognosis = Generally good with treatment, but depends on location and metastasis | |||
| frequency = Rare | |||
| deaths = Rare, but can occur if metastatic | |||
}} | |||
'''Paraganglioma''' is a rare type of [[neoplasm]] that originates from the [[paraganglia]], a group of cells that are dispersed throughout the body and are derived from the [[neural crest]]. These cells are associated with the [[autonomic nervous system]], which controls involuntary body functions such as heart rate and blood pressure. | '''Paraganglioma''' is a rare type of [[neoplasm]] that originates from the [[paraganglia]], a group of cells that are dispersed throughout the body and are derived from the [[neural crest]]. These cells are associated with the [[autonomic nervous system]], which controls involuntary body functions such as heart rate and blood pressure. | ||
[[File:SoftTissue Neural Paraganglioma 211 PA.JPG|left|thumb|oftTissue Neural Paraganglioma 211 PA]] | |||
[[File:SoftTissue Neural Paraganglioma 211 PA.JPG|thumb|oftTissue Neural Paraganglioma 211 PA]] | |||
== Classification == | == Classification == | ||
Paragangliomas can be classified based on their location in the body. They can occur in the head and neck, thorax, abdomen, and pelvis. The most common type is the [[carotid body tumor]], which is located at the bifurcation of the [[carotid artery]]. | Paragangliomas can be classified based on their location in the body. They can occur in the head and neck, thorax, abdomen, and pelvis. The most common type is the [[carotid body tumor]], which is located at the bifurcation of the [[carotid artery]]. | ||
<youtube> | <youtube> | ||
title='''{{PAGENAME}}''' | title='''{{PAGENAME}}''' | ||
movie_url=http://www.youtube.com/v/6ZPS5hdc-YI | movie_url=http://www.youtube.com/v/6ZPS5hdc-YI | ||
&rel=1 | &rel=1 | ||
| Line 16: | Line 36: | ||
height=600 | height=600 | ||
</youtube> | </youtube> | ||
== Signs and symptoms == | == Signs and symptoms == | ||
The symptoms of paraganglioma depend on the location of the tumor. Head and neck paragangliomas often present with symptoms such as a neck mass, [[tinnitus]], and [[cranial nerve]] deficits. Thoracic, abdominal, and pelvic paragangliomas can cause symptoms related to mass effect or [[catecholamine]] secretion, such as hypertension, palpitations, and sweating. | The symptoms of paraganglioma depend on the location of the tumor. Head and neck paragangliomas often present with symptoms such as a neck mass, [[tinnitus]], and [[cranial nerve]] deficits. Thoracic, abdominal, and pelvic paragangliomas can cause symptoms related to mass effect or [[catecholamine]] secretion, such as hypertension, palpitations, and sweating. | ||
== Diagnosis == | == Diagnosis == | ||
The diagnosis of paraganglioma is often made with imaging studies, such as [[computed tomography]] (CT) or [[magnetic resonance imaging]] (MRI). [[Biopsy]] is generally not recommended due to the risk of bleeding and catecholamine release. | The diagnosis of paraganglioma is often made with imaging studies, such as [[computed tomography]] (CT) or [[magnetic resonance imaging]] (MRI). [[Biopsy]] is generally not recommended due to the risk of bleeding and catecholamine release. | ||
== Treatment == | == Treatment == | ||
The treatment of paraganglioma depends on the location and size of the tumor, as well as the patient's overall health. Treatment options include surgery, radiation therapy, and medication to control symptoms. | The treatment of paraganglioma depends on the location and size of the tumor, as well as the patient's overall health. Treatment options include surgery, radiation therapy, and medication to control symptoms. | ||
== Prognosis == | == Prognosis == | ||
The prognosis of paraganglioma is generally good, but it can vary depending on the location and size of the tumor, as well as the patient's overall health. | The prognosis of paraganglioma is generally good, but it can vary depending on the location and size of the tumor, as well as the patient's overall health. | ||
== See also == | == See also == | ||
* [[Pheochromocytoma]] | * [[Pheochromocytoma]] | ||
* [[Neuroendocrine tumor]] | * [[Neuroendocrine tumor]] | ||
* [[Neuroblastoma]] | * [[Neuroblastoma]] | ||
== References == | == References == | ||
<references /> | <references /> | ||
[[Category:Neoplasms]] | [[Category:Neoplasms]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
[[Category:Endocrine neoplasms]] | [[Category:Endocrine neoplasms]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 15:37, 8 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics
| Paraganglioma | |
|---|---|
| Micrograph of a paraganglioma | |
| Synonyms | Glomus tumor, chemodectoma |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Hypertension, headache, palpitations, sweating, anxiety |
| Complications | Metastasis, pheochromocytoma |
| Onset | Typically in adulthood |
| Duration | Variable |
| Types | Carotid body tumor, glomus jugulare, glomus tympanicum, glomus vagale |
| Causes | Genetic mutations (e.g., SDHB, SDHD) |
| Risks | Family history, certain genetic syndromes |
| Diagnosis | Imaging studies, biopsy |
| Differential diagnosis | Pheochromocytoma, schwannoma, neurofibroma |
| Prevention | Genetic counseling for at-risk individuals |
| Treatment | Surgery, radiation therapy, chemotherapy |
| Medication | Alpha blockers, beta blockers |
| Prognosis | Generally good with treatment, but depends on location and metastasis |
| Frequency | Rare |
| Deaths | Rare, but can occur if metastatic |
Paraganglioma is a rare type of neoplasm that originates from the paraganglia, a group of cells that are dispersed throughout the body and are derived from the neural crest. These cells are associated with the autonomic nervous system, which controls involuntary body functions such as heart rate and blood pressure.
Classification[edit]
Paragangliomas can be classified based on their location in the body. They can occur in the head and neck, thorax, abdomen, and pelvis. The most common type is the carotid body tumor, which is located at the bifurcation of the carotid artery.
Signs and symptoms[edit]
The symptoms of paraganglioma depend on the location of the tumor. Head and neck paragangliomas often present with symptoms such as a neck mass, tinnitus, and cranial nerve deficits. Thoracic, abdominal, and pelvic paragangliomas can cause symptoms related to mass effect or catecholamine secretion, such as hypertension, palpitations, and sweating.
Diagnosis[edit]
The diagnosis of paraganglioma is often made with imaging studies, such as computed tomography (CT) or magnetic resonance imaging (MRI). Biopsy is generally not recommended due to the risk of bleeding and catecholamine release.
Treatment[edit]
The treatment of paraganglioma depends on the location and size of the tumor, as well as the patient's overall health. Treatment options include surgery, radiation therapy, and medication to control symptoms.
Prognosis[edit]
The prognosis of paraganglioma is generally good, but it can vary depending on the location and size of the tumor, as well as the patient's overall health.
See also[edit]
References[edit]
<references />
