Eccrine carcinoma: Difference between revisions
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{{Infobox medical condition | |||
| name = Eccrine carcinoma | |||
| image = [[File:SkinTumors-P8110577.JPG|left|thumb|Eccrine carcinoma]] | |||
| caption = Eccrine carcinoma on the skin | |||
| specialty = [[Dermatology]], [[Oncology]] | |||
| symptoms = [[Skin lesion]], [[nodule]], [[ulceration]] | |||
| onset = Typically in [[adulthood]] | |||
| duration = [[Chronic (medicine)|Chronic]] | |||
| causes = [[Genetic mutations]], [[environmental factors]] | |||
| risks = [[Sun exposure]], [[family history]] | |||
| diagnosis = [[Biopsy]], [[histopathology]] | |||
| differential = [[Basal cell carcinoma]], [[squamous cell carcinoma]], [[melanoma]] | |||
| treatment = [[Surgical excision]], [[radiation therapy]], [[chemotherapy]] | |||
| prognosis = Variable, depends on [[stage (cancer staging)|stage]] and [[treatment]] | |||
| frequency = Rare | |||
}} | |||
{{Short description|A rare type of sweat gland cancer}} | {{Short description|A rare type of sweat gland cancer}} | ||
'''Eccrine carcinoma''' is a rare form of [[skin cancer]] that originates from the [[eccrine sweat glands]]. These glands are responsible for the production of sweat and are distributed throughout the human body, with a higher concentration on the palms, soles, and forehead. | '''Eccrine carcinoma''' is a rare form of [[skin cancer]] that originates from the [[eccrine sweat glands]]. These glands are responsible for the production of sweat and are distributed throughout the human body, with a higher concentration on the palms, soles, and forehead. | ||
==Pathophysiology== | ==Pathophysiology== | ||
Eccrine carcinoma arises from the [[epithelial cells]] of the eccrine sweat glands. These tumors can exhibit a variety of histological patterns, making diagnosis challenging. The cancerous cells can invade surrounding tissues and, in some cases, metastasize to distant organs. | Eccrine carcinoma arises from the [[epithelial cells]] of the eccrine sweat glands. These tumors can exhibit a variety of histological patterns, making diagnosis challenging. The cancerous cells can invade surrounding tissues and, in some cases, metastasize to distant organs. | ||
==Clinical Presentation== | ==Clinical Presentation== | ||
Patients with eccrine carcinoma typically present with a slow-growing, painless nodule on the skin. The lesion may appear as a solitary, firm, and sometimes ulcerated mass. Common sites include the head, neck, and extremities, reflecting the distribution of eccrine glands. | Patients with eccrine carcinoma typically present with a slow-growing, painless nodule on the skin. The lesion may appear as a solitary, firm, and sometimes ulcerated mass. Common sites include the head, neck, and extremities, reflecting the distribution of eccrine glands. | ||
==Diagnosis== | ==Diagnosis== | ||
The diagnosis of eccrine carcinoma is primarily based on [[histopathological]] examination. A biopsy of the lesion is performed, and the tissue is analyzed under a microscope. Immunohistochemical staining may be used to differentiate eccrine carcinoma from other types of skin tumors. | The diagnosis of eccrine carcinoma is primarily based on [[histopathological]] examination. A biopsy of the lesion is performed, and the tissue is analyzed under a microscope. Immunohistochemical staining may be used to differentiate eccrine carcinoma from other types of skin tumors. | ||
==Treatment== | ==Treatment== | ||
The primary treatment for eccrine carcinoma is surgical excision with clear margins. In cases where the tumor is not resectable or has metastasized, additional treatments such as [[radiation therapy]] or [[chemotherapy]] may be considered. The choice of treatment depends on the stage of the cancer and the overall health of the patient. | The primary treatment for eccrine carcinoma is surgical excision with clear margins. In cases where the tumor is not resectable or has metastasized, additional treatments such as [[radiation therapy]] or [[chemotherapy]] may be considered. The choice of treatment depends on the stage of the cancer and the overall health of the patient. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for patients with eccrine carcinoma varies depending on the stage at diagnosis and the presence of metastasis. Early detection and complete surgical removal of the tumor generally result in a favorable outcome. However, advanced cases with distant metastasis have a poorer prognosis. | The prognosis for patients with eccrine carcinoma varies depending on the stage at diagnosis and the presence of metastasis. Early detection and complete surgical removal of the tumor generally result in a favorable outcome. However, advanced cases with distant metastasis have a poorer prognosis. | ||
==See also== | |||
== | |||
* [[Skin cancer]] | * [[Skin cancer]] | ||
* [[Sweat gland]] | * [[Sweat gland]] | ||
* [[Histopathology]] | * [[Histopathology]] | ||
* [[Oncology]] | * [[Oncology]] | ||
[[Category:Skin neoplasms]] | [[Category:Skin neoplasms]] | ||
[[Category:Rare cancers]] | [[Category:Rare cancers]] | ||
Latest revision as of 15:23, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Eccrine carcinoma | |
|---|---|
 | |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | Dermatology, Oncology |
| Symptoms | Skin lesion, nodule, ulceration |
| Complications | N/A |
| Onset | Typically in adulthood |
| Duration | Chronic |
| Types | N/A |
| Causes | Genetic mutations, environmental factors |
| Risks | Sun exposure, family history |
| Diagnosis | Biopsy, histopathology |
| Differential diagnosis | Basal cell carcinoma, squamous cell carcinoma, melanoma |
| Prevention | N/A |
| Treatment | Surgical excision, radiation therapy, chemotherapy |
| Medication | N/A |
| Prognosis | Variable, depends on stage and treatment |
| Frequency | Rare |
| Deaths | N/A |
A rare type of sweat gland cancer
Eccrine carcinoma is a rare form of skin cancer that originates from the eccrine sweat glands. These glands are responsible for the production of sweat and are distributed throughout the human body, with a higher concentration on the palms, soles, and forehead.
Pathophysiology[edit]
Eccrine carcinoma arises from the epithelial cells of the eccrine sweat glands. These tumors can exhibit a variety of histological patterns, making diagnosis challenging. The cancerous cells can invade surrounding tissues and, in some cases, metastasize to distant organs.
Clinical Presentation[edit]
Patients with eccrine carcinoma typically present with a slow-growing, painless nodule on the skin. The lesion may appear as a solitary, firm, and sometimes ulcerated mass. Common sites include the head, neck, and extremities, reflecting the distribution of eccrine glands.
Diagnosis[edit]
The diagnosis of eccrine carcinoma is primarily based on histopathological examination. A biopsy of the lesion is performed, and the tissue is analyzed under a microscope. Immunohistochemical staining may be used to differentiate eccrine carcinoma from other types of skin tumors.
Treatment[edit]
The primary treatment for eccrine carcinoma is surgical excision with clear margins. In cases where the tumor is not resectable or has metastasized, additional treatments such as radiation therapy or chemotherapy may be considered. The choice of treatment depends on the stage of the cancer and the overall health of the patient.
Prognosis[edit]
The prognosis for patients with eccrine carcinoma varies depending on the stage at diagnosis and the presence of metastasis. Early detection and complete surgical removal of the tumor generally result in a favorable outcome. However, advanced cases with distant metastasis have a poorer prognosis.
