Cancer of unknown primary origin: Difference between revisions
From WikiMD's Wellness Encyclopedia
CSV import |
CSV import |
||
| Line 1: | Line 1: | ||
[[File:Histopathology_of_undifferentiated_tumor_cells.jpg| | {{SI}} | ||
{{Infobox medical condition | |||
| name = Cancer of unknown primary origin | |||
| image = [[File:Histopathology_of_undifferentiated_tumor_cells.jpg|250px]] | |||
| caption = Histopathology of undifferentiated tumor cells | |||
| field = [[Oncology]] | |||
| synonyms = CUP, occult primary cancer | |||
| symptoms = [[Fatigue (medical)]], [[weight loss]], [[pain]], [[anorexia (symptom)]], [[night sweats]] | |||
| complications = [[Metastasis]], [[organ failure]] | |||
| onset = Typically in [[adulthood]] | |||
| duration = Variable | |||
| types = [[Adenocarcinoma]], [[squamous cell carcinoma]], [[neuroendocrine tumor]], [[poorly differentiated carcinoma]] | |||
| causes = Unknown | |||
| risks = [[Smoking]], [[alcohol consumption]], [[family history of cancer]] | |||
| diagnosis = [[Biopsy]], [[imaging studies]], [[blood tests]] | |||
| differential = [[Metastatic cancer]], [[primary cancer]], [[benign tumors]] | |||
| prevention = None specific | |||
| treatment = [[Chemotherapy]], [[radiation therapy]], [[surgery]], [[palliative care]] | |||
| prognosis = Generally poor | |||
| frequency = 2-5% of all cancer diagnoses | |||
}} | |||
'''Cancer of unknown primary origin''' (CUP), also known as '''occult primary cancer''', is a type of [[cancer]] in which [[metastatic]] cancer cells are found in the body, but the place where the cancer began (the primary site) is not known. CUP is a rare condition, accounting for approximately 3-5% of all cancer diagnoses. | |||
==Classification== | ==Classification== | ||
CUP can be classified based on the type of cells that are found in the metastatic tumors. The main types include: | CUP can be classified based on the type of cells that are found in the metastatic tumors. The main types include: | ||
| Line 7: | Line 27: | ||
* [[Neuroendocrine carcinoma]] of unknown primary | * [[Neuroendocrine carcinoma]] of unknown primary | ||
* [[Poorly differentiated carcinoma]] of unknown primary | * [[Poorly differentiated carcinoma]] of unknown primary | ||
==Symptoms== | ==Symptoms== | ||
The symptoms of CUP can vary widely depending on where the metastatic cancer cells are located. Common symptoms include: | The symptoms of CUP can vary widely depending on where the metastatic cancer cells are located. Common symptoms include: | ||
| Line 15: | Line 34: | ||
* Swollen lymph nodes | * Swollen lymph nodes | ||
* Loss of appetite | * Loss of appetite | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosing CUP involves a series of tests and procedures to try to locate the primary site of the cancer. These may include: | Diagnosing CUP involves a series of tests and procedures to try to locate the primary site of the cancer. These may include: | ||
| Line 22: | Line 40: | ||
* [[Blood tests]] | * [[Blood tests]] | ||
* [[Endoscopy]] | * [[Endoscopy]] | ||
==Treatment== | ==Treatment== | ||
The treatment for CUP depends on several factors, including the type of cancer cells found, the location of the metastases, and the patient's overall health. Common treatment options include: | The treatment for CUP depends on several factors, including the type of cancer cells found, the location of the metastases, and the patient's overall health. Common treatment options include: | ||
| Line 30: | Line 47: | ||
* [[Immunotherapy]] | * [[Immunotherapy]] | ||
* [[Surgery]] | * [[Surgery]] | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for patients with CUP varies widely and depends on several factors, including the type of cancer cells, the extent of the disease, and the patient's overall health. Generally, the prognosis is poorer compared to cancers with known primary sites. | The prognosis for patients with CUP varies widely and depends on several factors, including the type of cancer cells, the extent of the disease, and the patient's overall health. Generally, the prognosis is poorer compared to cancers with known primary sites. | ||
==Research== | ==Research== | ||
Ongoing research is focused on improving the diagnosis and treatment of CUP. Advances in [[molecular biology]] and [[genomics]] are helping to identify potential primary sites and develop targeted therapies. | Ongoing research is focused on improving the diagnosis and treatment of CUP. Advances in [[molecular biology]] and [[genomics]] are helping to identify potential primary sites and develop targeted therapies. | ||
==See also== | ==See also== | ||
* [[Metastasis]] | * [[Metastasis]] | ||
| Line 42: | Line 56: | ||
* [[Cancer staging]] | * [[Cancer staging]] | ||
* [[Cancer treatment]] | * [[Cancer treatment]] | ||
==References== | ==References== | ||
{{Reflist}} | {{Reflist}} | ||
==External links== | ==External links== | ||
{{Commons category|Cancer of unknown primary origin}} | {{Commons category|Cancer of unknown primary origin}} | ||
[[Category:Cancer]] | [[Category:Cancer]] | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
{{Oncology-stub}} | {{Oncology-stub}} | ||
Latest revision as of 00:22, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics
| Cancer of unknown primary origin | |
|---|---|
| |
| Synonyms | CUP, occult primary cancer |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Fatigue (medical), weight loss, pain, anorexia (symptom), night sweats |
| Complications | Metastasis, organ failure |
| Onset | Typically in adulthood |
| Duration | Variable |
| Types | Adenocarcinoma, squamous cell carcinoma, neuroendocrine tumor, poorly differentiated carcinoma |
| Causes | Unknown |
| Risks | Smoking, alcohol consumption, family history of cancer |
| Diagnosis | Biopsy, imaging studies, blood tests |
| Differential diagnosis | Metastatic cancer, primary cancer, benign tumors |
| Prevention | None specific |
| Treatment | Chemotherapy, radiation therapy, surgery, palliative care |
| Medication | N/A |
| Prognosis | Generally poor |
| Frequency | 2-5% of all cancer diagnoses |
| Deaths | N/A |
Cancer of unknown primary origin (CUP), also known as occult primary cancer, is a type of cancer in which metastatic cancer cells are found in the body, but the place where the cancer began (the primary site) is not known. CUP is a rare condition, accounting for approximately 3-5% of all cancer diagnoses.
Classification[edit]
CUP can be classified based on the type of cells that are found in the metastatic tumors. The main types include:
- Adenocarcinoma of unknown primary
- Squamous cell carcinoma of unknown primary
- Neuroendocrine carcinoma of unknown primary
- Poorly differentiated carcinoma of unknown primary
Symptoms[edit]
The symptoms of CUP can vary widely depending on where the metastatic cancer cells are located. Common symptoms include:
- Unexplained weight loss
- Fatigue
- Pain in the affected area
- Swollen lymph nodes
- Loss of appetite
Diagnosis[edit]
Diagnosing CUP involves a series of tests and procedures to try to locate the primary site of the cancer. These may include:
- Biopsy
- Imaging studies such as CT scan, MRI, and PET scan
- Blood tests
- Endoscopy
Treatment[edit]
The treatment for CUP depends on several factors, including the type of cancer cells found, the location of the metastases, and the patient's overall health. Common treatment options include:
Prognosis[edit]
The prognosis for patients with CUP varies widely and depends on several factors, including the type of cancer cells, the extent of the disease, and the patient's overall health. Generally, the prognosis is poorer compared to cancers with known primary sites.
Research[edit]
Ongoing research is focused on improving the diagnosis and treatment of CUP. Advances in molecular biology and genomics are helping to identify potential primary sites and develop targeted therapies.
See also[edit]
References[edit]
<references group="" responsive="1"></references>
External links[edit]
Wikimedia Commons has media related to
.
