Desquamative interstitial pneumonia: Difference between revisions
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{{Infobox medical condition | |||
| name = Desquamative interstitial pneumonia | |||
| image = [[File:Desquamative_interstitial_pneumonia_CT.jpg|alt=CT scan showing desquamative interstitial pneumonia]] | |||
| caption = CT scan showing desquamative interstitial pneumonia | |||
| field = [[Pulmonology]] | |||
| symptoms = [[Cough]], [[dyspnea]] | |||
| complications = [[Pulmonary fibrosis]] | |||
| onset = Typically [[adulthood]] | |||
| duration = Chronic | |||
| causes = [[Smoking]], [[environmental exposure]] | |||
| risks = [[Cigarette smoking]] | |||
| diagnosis = [[High-resolution computed tomography|HRCT]], [[lung biopsy]] | |||
| differential = [[Usual interstitial pneumonia]], [[nonspecific interstitial pneumonia]] | |||
| treatment = [[Smoking cessation]], [[corticosteroids]] | |||
| prognosis = Variable, can progress to [[pulmonary fibrosis]] | |||
| frequency = Rare | |||
}} | |||
'''Desquamative interstitial pneumonia''' (DIP) is a form of [[interstitial lung disease]] characterized by the accumulation of inflammatory cells and fibrosis within the lung tissue. It is considered a rare disease and primarily affects adults, particularly smokers. The condition was first described in 1965 by Liebow and Carrington. | '''Desquamative interstitial pneumonia''' (DIP) is a form of [[interstitial lung disease]] characterized by the accumulation of inflammatory cells and fibrosis within the lung tissue. It is considered a rare disease and primarily affects adults, particularly smokers. The condition was first described in 1965 by Liebow and Carrington. | ||
=== Signs and Symptoms === | === Signs and Symptoms === | ||
Patients with DIP often present with symptoms such as shortness of breath, cough, and fatigue. These symptoms are nonspecific and can be seen in other lung diseases as well. In some cases, patients may also experience weight loss and chest pain. It is important to note that the severity of symptoms can vary among individuals. | Patients with DIP often present with symptoms such as shortness of breath, cough, and fatigue. These symptoms are nonspecific and can be seen in other lung diseases as well. In some cases, patients may also experience weight loss and chest pain. It is important to note that the severity of symptoms can vary among individuals. | ||
=== Causes and Risk Factors === | === Causes and Risk Factors === | ||
The exact cause of DIP is unknown, but it is strongly associated with smoking. Studies have shown that the majority of patients diagnosed with DIP are current or former smokers. Other risk factors include exposure to environmental toxins and certain occupational hazards. | The exact cause of DIP is unknown, but it is strongly associated with smoking. Studies have shown that the majority of patients diagnosed with DIP are current or former smokers. Other risk factors include exposure to environmental toxins and certain occupational hazards. | ||
=== Diagnosis === | === Diagnosis === | ||
The diagnosis of DIP involves a combination of clinical evaluation, radiological imaging, and histopathological examination. High-resolution computed tomography (HRCT) scans of the chest can reveal characteristic findings such as ground-glass opacities and consolidation. However, a definitive diagnosis requires a lung biopsy, which typically shows the presence of macrophages within the alveoli. | The diagnosis of DIP involves a combination of clinical evaluation, radiological imaging, and histopathological examination. High-resolution computed tomography (HRCT) scans of the chest can reveal characteristic findings such as ground-glass opacities and consolidation. However, a definitive diagnosis requires a lung biopsy, which typically shows the presence of macrophages within the alveoli. | ||
=== Treatment === | === Treatment === | ||
The primary treatment for DIP is smoking cessation. Quitting smoking can help slow down the progression of the disease and improve lung function. In addition, patients may be prescribed corticosteroids to reduce inflammation and manage symptoms. Oxygen therapy may also be necessary in cases of severe respiratory impairment. | The primary treatment for DIP is smoking cessation. Quitting smoking can help slow down the progression of the disease and improve lung function. In addition, patients may be prescribed corticosteroids to reduce inflammation and manage symptoms. Oxygen therapy may also be necessary in cases of severe respiratory impairment. | ||
=== Prognosis === | === Prognosis === | ||
The prognosis for DIP varies depending on the individual and the stage of the disease at the time of diagnosis. With early detection and appropriate treatment, some patients may experience a significant improvement in lung function and quality of life. However, in advanced cases, the prognosis may be poor, with a higher risk of developing complications such as respiratory failure. | The prognosis for DIP varies depending on the individual and the stage of the disease at the time of diagnosis. With early detection and appropriate treatment, some patients may experience a significant improvement in lung function and quality of life. However, in advanced cases, the prognosis may be poor, with a higher risk of developing complications such as respiratory failure. | ||
=== References === | === References === | ||
<references /> | <references /> | ||
== See Also == | == See Also == | ||
* [[Interstitial lung disease]] | * [[Interstitial lung disease]] | ||
* [[Smoking cessation]] | * [[Smoking cessation]] | ||
* [[High-resolution computed tomography]] | * [[High-resolution computed tomography]] | ||
* [[Lung biopsy]] | * [[Lung biopsy]] | ||
== External Links == | == External Links == | ||
* [https://www.ncbi.nlm.nih.gov/books/NBK537038/ Desquamative Interstitial Pneumonia - StatPearls] | * [https://www.ncbi.nlm.nih.gov/books/NBK537038/ Desquamative Interstitial Pneumonia - StatPearls] | ||
* [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517452/ Desquamative Interstitial Pneumonia - Radiopaedia] | * [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517452/ Desquamative Interstitial Pneumonia - Radiopaedia] | ||
[[Category:Lung diseases]] | [[Category:Lung diseases]] | ||
[[Category:Respiratory diseases]] | [[Category:Respiratory diseases]] | ||
Latest revision as of 18:44, 5 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Desquamative interstitial pneumonia | |
|---|---|
| |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Cough, dyspnea |
| Complications | Pulmonary fibrosis |
| Onset | Typically adulthood |
| Duration | Chronic |
| Types | N/A |
| Causes | Smoking, environmental exposure |
| Risks | Cigarette smoking |
| Diagnosis | HRCT, lung biopsy |
| Differential diagnosis | Usual interstitial pneumonia, nonspecific interstitial pneumonia |
| Prevention | N/A |
| Treatment | Smoking cessation, corticosteroids |
| Medication | N/A |
| Prognosis | Variable, can progress to pulmonary fibrosis |
| Frequency | Rare |
| Deaths | N/A |
Desquamative interstitial pneumonia (DIP) is a form of interstitial lung disease characterized by the accumulation of inflammatory cells and fibrosis within the lung tissue. It is considered a rare disease and primarily affects adults, particularly smokers. The condition was first described in 1965 by Liebow and Carrington.
Signs and Symptoms[edit]
Patients with DIP often present with symptoms such as shortness of breath, cough, and fatigue. These symptoms are nonspecific and can be seen in other lung diseases as well. In some cases, patients may also experience weight loss and chest pain. It is important to note that the severity of symptoms can vary among individuals.
Causes and Risk Factors[edit]
The exact cause of DIP is unknown, but it is strongly associated with smoking. Studies have shown that the majority of patients diagnosed with DIP are current or former smokers. Other risk factors include exposure to environmental toxins and certain occupational hazards.
Diagnosis[edit]
The diagnosis of DIP involves a combination of clinical evaluation, radiological imaging, and histopathological examination. High-resolution computed tomography (HRCT) scans of the chest can reveal characteristic findings such as ground-glass opacities and consolidation. However, a definitive diagnosis requires a lung biopsy, which typically shows the presence of macrophages within the alveoli.
Treatment[edit]
The primary treatment for DIP is smoking cessation. Quitting smoking can help slow down the progression of the disease and improve lung function. In addition, patients may be prescribed corticosteroids to reduce inflammation and manage symptoms. Oxygen therapy may also be necessary in cases of severe respiratory impairment.
Prognosis[edit]
The prognosis for DIP varies depending on the individual and the stage of the disease at the time of diagnosis. With early detection and appropriate treatment, some patients may experience a significant improvement in lung function and quality of life. However, in advanced cases, the prognosis may be poor, with a higher risk of developing complications such as respiratory failure.
References[edit]
<references />
