Cutaneous small-vessel vasculitis: Difference between revisions

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{{SI}}
{{Infobox medical condition
| name          = Cutaneous small-vessel vasculitis
| image          = [[File:LV22010.JPG|left|thumb|Cutaneous small-vessel vasculitis]]
| caption        = Cutaneous small-vessel vasculitis on the skin
| field          = [[Rheumatology]], [[Dermatology]]
| synonyms      = Leukocytoclastic vasculitis, hypersensitivity vasculitis
| symptoms      = [[Purpura]], [[Petechiae]], [[Urticaria]], [[Blisters]], [[Ulcers]]
| complications  = [[Kidney damage]], [[Gastrointestinal bleeding]], [[Peripheral neuropathy]]
| onset          = Sudden
| duration      = Variable
| causes        = [[Infection]], [[Medication]], [[Autoimmune disease]]
| risks          = [[Age]], [[Genetic predisposition]], [[Environmental factors]]
| diagnosis      = [[Skin biopsy]], [[Blood tests]]
| differential  = [[Henoch-Schönlein purpura]], [[Systemic vasculitis]], [[Drug eruption]]
| treatment      = [[Corticosteroids]], [[Immunosuppressants]], [[Antihistamines]]
| prognosis      = Generally good with treatment
| frequency      = Common
}}
'''Cutaneous small-vessel vasculitis''' (CSVV), also known as '''hypersensitivity vasculitis''', '''hypersensitivity angiitis''', and '''leukocytoclastic vasculitis''', is a condition that causes inflammation and damage to the small blood vessels in the skin. This can result in a variety of symptoms, including red or purple spots on the skin, itching, and in some cases, systemic symptoms such as fever and joint pain.
'''Cutaneous small-vessel vasculitis''' (CSVV), also known as '''hypersensitivity vasculitis''', '''hypersensitivity angiitis''', and '''leukocytoclastic vasculitis''', is a condition that causes inflammation and damage to the small blood vessels in the skin. This can result in a variety of symptoms, including red or purple spots on the skin, itching, and in some cases, systemic symptoms such as fever and joint pain.
== Causes ==
== Causes ==
CSVV is often associated with reactions to medications, infections, or other diseases. It can also occur as a result of an autoimmune response, where the body's immune system mistakenly attacks its own tissues.
CSVV is often associated with reactions to medications, infections, or other diseases. It can also occur as a result of an autoimmune response, where the body's immune system mistakenly attacks its own tissues.
== Symptoms ==
== Symptoms ==
The most common symptom of CSVV is a rash, which typically appears as red or purple spots (petechiae) or larger patches (purpura) on the skin. The rash is often located on the lower legs, but can appear anywhere on the body. Other symptoms can include itching, burning, or pain at the site of the rash, and in some cases, systemic symptoms such as fever, fatigue, and joint pain.
The most common symptom of CSVV is a rash, which typically appears as red or purple spots (petechiae) or larger patches (purpura) on the skin. The rash is often located on the lower legs, but can appear anywhere on the body. Other symptoms can include itching, burning, or pain at the site of the rash, and in some cases, systemic symptoms such as fever, fatigue, and joint pain.
== Diagnosis ==
== Diagnosis ==
Diagnosis of CSVV is typically based on the appearance of the rash and a patient's medical history. In some cases, a skin biopsy may be performed to confirm the diagnosis.
Diagnosis of CSVV is typically based on the appearance of the rash and a patient's medical history. In some cases, a skin biopsy may be performed to confirm the diagnosis.
== Treatment ==
== Treatment ==
Treatment for CSVV is aimed at reducing inflammation and managing symptoms. This can include the use of nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, or other immunosuppressive medications. In some cases, treating the underlying cause of the vasculitis, such as discontinuing a medication or treating an infection, can also help to resolve the condition.
Treatment for CSVV is aimed at reducing inflammation and managing symptoms. This can include the use of nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, or other immunosuppressive medications. In some cases, treating the underlying cause of the vasculitis, such as discontinuing a medication or treating an infection, can also help to resolve the condition.
 
== Gallery ==
<gallery>
File:Micrograph of cutaneous small-vessel vasculitis.jpg|Micrograph of cutaneous small-vessel vasculitis
File:LV1,2010.JPG|Cutaneous small-vessel vasculitis
File:LV22010.JPG|Cutaneous small-vessel vasculitis
File:Leukocytoclastic vasculitis caused by reaction to minocycline.jpg|Leukocytoclastic vasculitis caused by reaction to minocycline
File:LV4.JPG|Cutaneous small-vessel vasculitis
</gallery>
== See also ==
== See also ==
* [[Vasculitis]]
* [[Vasculitis]]
* [[Autoimmune disease]]
* [[Autoimmune disease]]
* [[Skin biopsy]]
* [[Skin biopsy]]
== References ==
== References ==
<references />
<references />
[[Category:Vasculitis]]
[[Category:Vasculitis]]
[[Category:Autoimmune diseases]]
[[Category:Autoimmune diseases]]
[[Category:Skin conditions]]
[[Category:Skin conditions]]
{{stub}}
{{stub}}
<gallery>
File:LV22010.JPG|Cutaneous small-vessel vasculitis
File:Micrograph of cutaneous small-vessel vasculitis.jpg|Micrograph of cutaneous small-vessel vasculitis
File:LV1,2010.JPG|Cutaneous small-vessel vasculitis
File:LV22010.JPG|Cutaneous small-vessel vasculitis
File:Leukocytoclastic vasculitis caused by reaction to minocycline.jpg|Leukocytoclastic vasculitis caused by reaction to minocycline
File:LV4.JPG|Cutaneous small-vessel vasculitis
</gallery>

Latest revision as of 13:31, 5 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Cutaneous small-vessel vasculitis
Cutaneous small-vessel vasculitis
Synonyms Leukocytoclastic vasculitis, hypersensitivity vasculitis
Pronounce N/A
Specialty N/A
Symptoms Purpura, Petechiae, Urticaria, Blisters, Ulcers
Complications Kidney damage, Gastrointestinal bleeding, Peripheral neuropathy
Onset Sudden
Duration Variable
Types N/A
Causes Infection, Medication, Autoimmune disease
Risks Age, Genetic predisposition, Environmental factors
Diagnosis Skin biopsy, Blood tests
Differential diagnosis Henoch-Schönlein purpura, Systemic vasculitis, Drug eruption
Prevention N/A
Treatment Corticosteroids, Immunosuppressants, Antihistamines
Medication N/A
Prognosis Generally good with treatment
Frequency Common
Deaths N/A


Cutaneous small-vessel vasculitis (CSVV), also known as hypersensitivity vasculitis, hypersensitivity angiitis, and leukocytoclastic vasculitis, is a condition that causes inflammation and damage to the small blood vessels in the skin. This can result in a variety of symptoms, including red or purple spots on the skin, itching, and in some cases, systemic symptoms such as fever and joint pain.

Causes[edit]

CSVV is often associated with reactions to medications, infections, or other diseases. It can also occur as a result of an autoimmune response, where the body's immune system mistakenly attacks its own tissues.

Symptoms[edit]

The most common symptom of CSVV is a rash, which typically appears as red or purple spots (petechiae) or larger patches (purpura) on the skin. The rash is often located on the lower legs, but can appear anywhere on the body. Other symptoms can include itching, burning, or pain at the site of the rash, and in some cases, systemic symptoms such as fever, fatigue, and joint pain.

Diagnosis[edit]

Diagnosis of CSVV is typically based on the appearance of the rash and a patient's medical history. In some cases, a skin biopsy may be performed to confirm the diagnosis.

Treatment[edit]

Treatment for CSVV is aimed at reducing inflammation and managing symptoms. This can include the use of nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, or other immunosuppressive medications. In some cases, treating the underlying cause of the vasculitis, such as discontinuing a medication or treating an infection, can also help to resolve the condition.

Gallery[edit]

See also[edit]

References[edit]

<references />

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