Congenital syphilis: Difference between revisions
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{{Infobox medical condition | |||
| name = Congenital syphilis | |||
| image = [[File:Hutchinson_teeth_congenital_syphilis_PHIL_2385.rsh.jpg|left|thumb|Hutchinson's teeth, a sign of congenital syphilis]] | |||
| caption = Hutchinson's teeth, a sign of congenital syphilis | |||
| field = [[Infectious disease]] | |||
| symptoms = [[Rash]], [[fever]], [[hepatosplenomegaly]], [[jaundice]], [[anemia]], [[deafness]], [[Hutchinson's teeth]] | |||
| complications = [[Neurological disorders]], [[bone deformities]], [[developmental delays]] | |||
| onset = At birth or within the first few months of life | |||
| duration = Chronic | |||
| causes = [[Treponema pallidum]] infection transmitted from mother to child | |||
| risks = Untreated [[syphilis]] in the mother | |||
| diagnosis = [[Blood test]], [[physical examination]], [[X-ray]] | |||
| differential = [[Neonatal sepsis]], [[rubella]], [[toxoplasmosis]] | |||
| prevention = [[Prenatal care]], [[screening]] and treatment of syphilis in pregnant women | |||
| treatment = [[Antibiotics]], typically [[penicillin]] | |||
| prognosis = Variable, depends on severity and timing of treatment | |||
| frequency = Varies by region, higher in areas with limited access to prenatal care | |||
}} | |||
= Congenital Syphilis = | = Congenital Syphilis = | ||
[[File:Congenital syphilis. Mulberry molar.jpg|left|thumb|Microscopic image of Treponema pallidum, the bacterium causing congenital syphilis.]] | |||
[[File:Congenital syphilis. Mulberry molar.jpg|thumb | |||
'''Congenital syphilis''' is a life-threatening bacterial infection in newborns, caused by the bacterium ''[[Treponema pallidum]]''. It occurs when a mother with syphilis transmits the infection to her baby during pregnancy. | '''Congenital syphilis''' is a life-threatening bacterial infection in newborns, caused by the bacterium ''[[Treponema pallidum]]''. It occurs when a mother with syphilis transmits the infection to her baby during pregnancy. | ||
== Transmission == | == Transmission == | ||
Congenital syphilis is transmitted from an infected mother to her baby through the placenta. The risk of transmission depends on the stage of the mother's syphilis infection and whether she has received treatment. | Congenital syphilis is transmitted from an infected mother to her baby through the placenta. The risk of transmission depends on the stage of the mother's syphilis infection and whether she has received treatment. | ||
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== Signs and Symptoms == | == Signs and Symptoms == | ||
Infants with congenital syphilis may exhibit symptoms such as: | Infants with congenital syphilis may exhibit symptoms such as: | ||
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* Skin rash | * Skin rash | ||
* Pneumonia | * Pneumonia | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of congenital syphilis typically involves: | Diagnosis of congenital syphilis typically involves: | ||
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* Physical examination for characteristic symptoms | * Physical examination for characteristic symptoms | ||
* Bone X-rays to detect bone abnormalities | * Bone X-rays to detect bone abnormalities | ||
== Treatment == | == Treatment == | ||
Early treatment is crucial and typically involves: | Early treatment is crucial and typically involves: | ||
* Intravenous or intramuscular penicillin therapy | * Intravenous or intramuscular penicillin therapy | ||
* Treatment of the infected mother to prevent re-infection | * Treatment of the infected mother to prevent re-infection | ||
== Prevention == | == Prevention == | ||
Prevention strategies include: | Prevention strategies include: | ||
* Routine syphilis screening for all pregnant women | * Routine syphilis screening for all pregnant women | ||
* Immediate treatment for women diagnosed with syphilis during pregnancy | * Immediate treatment for women diagnosed with syphilis during pregnancy | ||
== External Links == | == External Links == | ||
* [https://www.cdc.gov/std/syphilis/stdfact-congenital-syphilis.htm CDC: Congenital Syphilis] | * [https://www.cdc.gov/std/syphilis/stdfact-congenital-syphilis.htm CDC: Congenital Syphilis] | ||
* [https://www.who.int/news-room/fact-sheets/detail/syphilis World Health Organization: Syphilis] | * [https://www.who.int/news-room/fact-sheets/detail/syphilis World Health Organization: Syphilis] | ||
[[Category:Bacterial diseases]] | [[Category:Bacterial diseases]] | ||
[[Category:Neonatology]] | [[Category:Neonatology]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 02:18, 5 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Congenital syphilis | |
|---|---|
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Rash, fever, hepatosplenomegaly, jaundice, anemia, deafness, Hutchinson's teeth |
| Complications | Neurological disorders, bone deformities, developmental delays |
| Onset | At birth or within the first few months of life |
| Duration | Chronic |
| Types | N/A |
| Causes | Treponema pallidum infection transmitted from mother to child |
| Risks | Untreated syphilis in the mother |
| Diagnosis | Blood test, physical examination, X-ray |
| Differential diagnosis | Neonatal sepsis, rubella, toxoplasmosis |
| Prevention | Prenatal care, screening and treatment of syphilis in pregnant women |
| Treatment | Antibiotics, typically penicillin |
| Medication | N/A |
| Prognosis | Variable, depends on severity and timing of treatment |
| Frequency | Varies by region, higher in areas with limited access to prenatal care |
| Deaths | N/A |
Congenital Syphilis[edit]

Congenital syphilis is a life-threatening bacterial infection in newborns, caused by the bacterium Treponema pallidum. It occurs when a mother with syphilis transmits the infection to her baby during pregnancy.
Transmission[edit]
Congenital syphilis is transmitted from an infected mother to her baby through the placenta. The risk of transmission depends on the stage of the mother's syphilis infection and whether she has received treatment.
Signs and Symptoms[edit]
Infants with congenital syphilis may exhibit symptoms such as:
- Irritability
- Fever
- Failure to thrive
- Saddle nose deformity
- Skin rash
- Pneumonia
Diagnosis[edit]
Diagnosis of congenital syphilis typically involves:
- Blood tests for syphilis antibodies
- Physical examination for characteristic symptoms
- Bone X-rays to detect bone abnormalities
Treatment[edit]
Early treatment is crucial and typically involves:
- Intravenous or intramuscular penicillin therapy
- Treatment of the infected mother to prevent re-infection
Prevention[edit]
Prevention strategies include:
- Routine syphilis screening for all pregnant women
- Immediate treatment for women diagnosed with syphilis during pregnancy



