Atypical ductal hyperplasia: Difference between revisions
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[[Image:Atypical_ductal_hyperplasia_-_low_mag.jpg_|Atypical ductal hyperplasia - low mag|thumb]] [[Image:Atypical_ductal_hyperplasia_-_high_mag.jpg_|Atypical ductal hyperplasia - high mag|thumb | {{SI}} | ||
{{Infobox medical condition | |||
| name = Atypical ductal hyperplasia | |||
| image = [[File:Atypical_ductal_hyperplasia_-_very_low_mag.jpg|alt=Micrograph of atypical ductal hyperplasia]] | |||
| caption = Micrograph of atypical ductal hyperplasia | |||
| field = [[Oncology]], [[Pathology]] | |||
| synonyms = ADH | |||
| symptoms = Often asymptomatic, may be detected on [[mammography]] | |||
| complications = Increased risk of [[breast cancer]] | |||
| onset = Typically diagnosed in women aged 40-60 | |||
| duration = Chronic | |||
| causes = Abnormal proliferation of [[ductal epithelial cells]] | |||
| risks = Family history of breast cancer, [[hormone replacement therapy]] | |||
| diagnosis = [[Biopsy]], [[histopathology]] | |||
| differential = [[Ductal carcinoma in situ]], [[usual ductal hyperplasia]] | |||
| prevention = Regular [[mammograms]], lifestyle modifications | |||
| treatment = Surveillance, [[surgical excision]] | |||
| medication = [[Tamoxifen]] or other [[selective estrogen receptor modulators]] | |||
| prognosis = Good with monitoring, but increased risk of breast cancer | |||
| frequency = Found in approximately 5-10% of breast biopsies | |||
}} | |||
[[Image:Atypical_ductal_hyperplasia_-_low_mag.jpg_|Atypical ductal hyperplasia - low mag|left|thumb]] [[Image:Atypical_ductal_hyperplasia_-_high_mag.jpg_|Atypical ductal hyperplasia - high mag|left|thumb]] [[File:Atypical_ductal_hyperplasia_with_immunotyping.jpg|Atypical ductal hyperplasia with immunotyping|left|thumb]] '''Atypical Ductal Hyperplasia (ADH)''' is a condition characterized by the abnormal proliferation of cells within the [[milk ducts]] of the [[breast]]. It is considered a [[precancerous condition]], meaning that while it is not cancer, it has the potential to develop into a more serious form of [[breast cancer]] if left untreated. ADH is often discovered during a [[mammogram]] as part of routine [[breast cancer screening]] or following an investigation of a breast lump. | |||
== Diagnosis == | == Diagnosis == | ||
The diagnosis of ADH is typically made through a combination of imaging tests and a biopsy. Imaging tests, such as a [[mammogram]] or [[ultrasound]], can identify areas of abnormal tissue in the breast. However, a definitive diagnosis requires a biopsy, where a small sample of breast tissue is removed and examined under a microscope by a pathologist. The presence of atypical cells that have not spread outside the ducts characterizes ADH. | The diagnosis of ADH is typically made through a combination of imaging tests and a biopsy. Imaging tests, such as a [[mammogram]] or [[ultrasound]], can identify areas of abnormal tissue in the breast. However, a definitive diagnosis requires a biopsy, where a small sample of breast tissue is removed and examined under a microscope by a pathologist. The presence of atypical cells that have not spread outside the ducts characterizes ADH. | ||
== Risk Factors == | == Risk Factors == | ||
Several risk factors are associated with the development of ADH, including age, family history of breast cancer, personal history of breast lesions, and certain genetic mutations. Women with ADH have an increased risk of developing breast cancer in the future, making it important to identify and monitor this condition early. | Several risk factors are associated with the development of ADH, including age, family history of breast cancer, personal history of breast lesions, and certain genetic mutations. Women with ADH have an increased risk of developing breast cancer in the future, making it important to identify and monitor this condition early. | ||
== Treatment and Management == | == Treatment and Management == | ||
The treatment for ADH often involves surgical removal of the affected tissue, typically through a procedure known as a lumpectomy. In some cases, particularly when ADH is found alongside other high-risk conditions, more extensive surgery may be recommended. Following surgery, patients are usually advised to undergo regular breast cancer screening to monitor for the development of invasive cancer. | The treatment for ADH often involves surgical removal of the affected tissue, typically through a procedure known as a lumpectomy. In some cases, particularly when ADH is found alongside other high-risk conditions, more extensive surgery may be recommended. Following surgery, patients are usually advised to undergo regular breast cancer screening to monitor for the development of invasive cancer. | ||
== Prognosis == | == Prognosis == | ||
While ADH itself is not cancer, it indicates an increased risk of developing breast cancer in the future. With appropriate treatment and monitoring, the prognosis for individuals with ADH is generally good. Early detection and management of ADH are crucial for preventing the progression to more serious forms of breast cancer. | While ADH itself is not cancer, it indicates an increased risk of developing breast cancer in the future. With appropriate treatment and monitoring, the prognosis for individuals with ADH is generally good. Early detection and management of ADH are crucial for preventing the progression to more serious forms of breast cancer. | ||
== See Also == | == See Also == | ||
* [[Breast cancer]] | * [[Breast cancer]] | ||
| Line 18: | Line 34: | ||
* [[Lumpectomy]] | * [[Lumpectomy]] | ||
* [[Breast biopsy]] | * [[Breast biopsy]] | ||
[[Category:Breast diseases]] | [[Category:Breast diseases]] | ||
[[Category:Pathology]] | [[Category:Pathology]] | ||
{{medicine-stub}} | {{medicine-stub}} | ||
Latest revision as of 17:03, 4 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Atypical ductal hyperplasia | |
|---|---|
| |
| Synonyms | ADH |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Often asymptomatic, may be detected on mammography |
| Complications | Increased risk of breast cancer |
| Onset | Typically diagnosed in women aged 40-60 |
| Duration | Chronic |
| Types | N/A |
| Causes | Abnormal proliferation of ductal epithelial cells |
| Risks | Family history of breast cancer, hormone replacement therapy |
| Diagnosis | Biopsy, histopathology |
| Differential diagnosis | Ductal carcinoma in situ, usual ductal hyperplasia |
| Prevention | Regular mammograms, lifestyle modifications |
| Treatment | Surveillance, surgical excision |
| Medication | Tamoxifen or other selective estrogen receptor modulators |
| Prognosis | Good with monitoring, but increased risk of breast cancer |
| Frequency | Found in approximately 5-10% of breast biopsies |
| Deaths | N/A |
Atypical Ductal Hyperplasia (ADH) is a condition characterized by the abnormal proliferation of cells within the milk ducts of the breast. It is considered a precancerous condition, meaning that while it is not cancer, it has the potential to develop into a more serious form of breast cancer if left untreated. ADH is often discovered during a mammogram as part of routine breast cancer screening or following an investigation of a breast lump.
Diagnosis[edit]
The diagnosis of ADH is typically made through a combination of imaging tests and a biopsy. Imaging tests, such as a mammogram or ultrasound, can identify areas of abnormal tissue in the breast. However, a definitive diagnosis requires a biopsy, where a small sample of breast tissue is removed and examined under a microscope by a pathologist. The presence of atypical cells that have not spread outside the ducts characterizes ADH.
Risk Factors[edit]
Several risk factors are associated with the development of ADH, including age, family history of breast cancer, personal history of breast lesions, and certain genetic mutations. Women with ADH have an increased risk of developing breast cancer in the future, making it important to identify and monitor this condition early.
Treatment and Management[edit]
The treatment for ADH often involves surgical removal of the affected tissue, typically through a procedure known as a lumpectomy. In some cases, particularly when ADH is found alongside other high-risk conditions, more extensive surgery may be recommended. Following surgery, patients are usually advised to undergo regular breast cancer screening to monitor for the development of invasive cancer.
Prognosis[edit]
While ADH itself is not cancer, it indicates an increased risk of developing breast cancer in the future. With appropriate treatment and monitoring, the prognosis for individuals with ADH is generally good. Early detection and management of ADH are crucial for preventing the progression to more serious forms of breast cancer.
See Also[edit]
