Reversible cerebral vasoconstriction syndrome

Reversible cerebral vasoconstriction syndrome
Synonyms	Call-Fleming syndrome, Thunderclap headache
Pronounce	N/A
Specialty	N/A
Symptoms	Severe headache, nausea, vomiting, visual disturbances, seizures
Complications	Stroke, subarachnoid hemorrhage
Onset	Sudden
Duration	Days to weeks
Types	N/A
Causes	Unknown, possible triggers include vasoactive substances, pregnancy, migraine, physical exertion
Risks	Female gender, migraine history, postpartum period
Diagnosis	Clinical diagnosis, MRI, angiography
Differential diagnosis	Subarachnoid hemorrhage, migraine, cerebral vasculitis
Prevention	N/A
Treatment	Calcium channel blockers, pain management, hydration
Medication	N/A
Prognosis	Generally good with treatment
Frequency	Rare
Deaths	N/A

Reversible cerebral vasoconstriction syndrome (RCVS) is a rare condition characterized by a group of disorders featuring reversible constriction of the cerebral arteries. The primary symptom of RCVS is a sudden, severe headache, often described as the "worst headache of my life".

Symptoms

The most common symptom of RCVS is a sudden, severe headache, often described as a "thunderclap headache". This headache is typically at its worst at onset and may be associated with nausea, vomiting, and sensitivity to light. Other symptoms can include seizures, focal neurological deficits, and visual disturbances.

Causes

The exact cause of RCVS is unknown. However, it has been associated with various conditions and triggers, including pregnancy, the postpartum period, exposure to certain drugs (such as selective serotonin reuptake inhibitors, triptans, and pseudoephedrine), and certain medical procedures.

Diagnosis

Diagnosis of RCVS is typically based on the clinical presentation and imaging findings. The diagnosis can be confirmed by demonstrating the reversibility of the vasoconstriction on follow-up imaging.

Treatment

Treatment for RCVS is primarily supportive, as the condition is self-limiting and typically resolves on its own within three months. However, in some cases, medication may be used to help manage symptoms and prevent complications.

Prognosis

The prognosis for RCVS is generally good, with most patients experiencing complete resolution of symptoms within three months. However, in rare cases, RCVS can lead to serious complications such as stroke or brain hemorrhage.

See also

• Cerebral vasospasm
• Thunderclap headache
• Stroke
• Brain hemorrhage

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