Brodmann area 33: Difference between revisions

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'''Brodmann area 33''' (BA33), also known as the '''pre-cingulate area''', is a region of the [[cerebral cortex]] located in the [[medial frontal lobe]] of the [[brain]]. It is part of the [[cingulate cortex]] and is situated anterior to the [[Brodmann area 24|area 24]]. This area is involved in various cognitive and emotional processes, including [[pain processing]], [[emotion regulation]], and [[autonomic function]].
{{Short description|Brodmann area 33 is a subdivision of the cerebral cortex in the human brain.}}


== Anatomy ==
== Brodmann Area 33 ==
Brodmann area 33 is defined based on its [[cytoarchitecture]] rather than its exact anatomical boundaries, which can vary between individuals. It is located in the [[cingulate gyrus]], specifically in the anterior portion of the cingulate, adjacent to the [[corpus callosum]]. This area is characterized by a distinct layer IV, which is not as prominent in other parts of the cingulate cortex.
[[File:Brodmann_area_33_animation_small.gif|Brodmann area 33 animation|thumb|right]]
'''Brodmann area 33''' is a subdivision of the [[cerebral cortex]] in the human brain, defined based on its distinct [[cytoarchitecture]]. It is part of the [[cingulate cortex]], which is involved in various functions including emotion formation and processing, learning, and memory.


== Function ==
=== Location ===
The precise functions of BA33 are still under investigation, but it is known to play a role in integrating [[sensory information]] with [[emotional response]]s. It is involved in the processing of pain and is thought to modulate the emotional aspects of pain perception. Additionally, BA33 has been implicated in [[autonomic nervous system]] regulation, influencing heart rate and blood pressure.
Brodmann area 33 is located in the [[medial]] aspect of the brain, within the [[cingulate gyrus]]. It is situated anteriorly to [[Brodmann area 24]] and is considered a part of the [[limbic system]]. This area is found in the [[medial wall]] of the [[hemisphere]], and it is often associated with the [[anterior cingulate cortex]].


BA33 also plays a role in [[social cognition]], including the perception of [[social exclusion]] and the processing of [[empathy]]. This suggests its involvement in complex emotional and social behaviors.
=== Cytoarchitecture ===
[[File:Brodmann_Cytoarchitectonics_33.png|Brodmann area 33 cytoarchitectonics|thumb|left]]
The cytoarchitecture of Brodmann area 33 is characterized by a thin cortical layer with a relatively simple structure compared to other cortical areas. It is distinguished by its lack of a distinct layer IV, which is typical of the [[granular cortex]]. The neurons in this area are densely packed, and the area is involved in processing emotional and autonomic information.


== Clinical Significance ==
=== Function ===
Alterations in the activity or structure of Brodmann area 33 have been associated with various [[neuropsychiatric disorders]], including [[depression]], [[anxiety disorders]], and [[schizophrenia]]. It is thought that dysregulation of this area may contribute to the emotional and cognitive symptoms observed in these conditions.
Brodmann area 33 is involved in the processing of emotional and autonomic responses. It plays a role in the regulation of [[emotional behavior]], [[pain perception]], and [[autonomic functions]]. The area is also implicated in the integration of [[cognitive]] and [[emotional]] information, contributing to the [[emotional regulation]] and [[decision-making]] processes.


Furthermore, because of its role in pain perception, BA33 is a target for research into chronic pain conditions and the development of interventions that may modulate its activity to provide relief.
=== Clinical Significance ===
Dysfunction in Brodmann area 33 has been associated with various [[neuropsychiatric disorders]], including [[depression]], [[anxiety disorders]], and [[schizophrenia]]. Its role in emotional processing makes it a target for research in understanding the neural basis of these conditions.


== Research ==
== Related Pages ==
Ongoing research aims to further elucidate the specific functions of Brodmann area 33, its connections with other brain regions, and its involvement in various neurological and psychiatric conditions. Advanced imaging techniques, such as [[functional magnetic resonance imaging]] (fMRI) and [[positron emission tomography]] (PET), are commonly used to study this area in both healthy and clinical populations.
* [[Brodmann area 24]]
* [[Cingulate cortex]]
* [[Limbic system]]
* [[Anterior cingulate cortex]]


== See Also ==
[[File:Brodmann_area_33_medial.jpg|Brodmann area 33 medial view|thumb|right]]
* [[Cingulate cortex]]
* [[Cerebral cortex]]
* [[Neuroanatomy]]
* [[Neuropsychiatry]]


== References ==
{{Brodmann areas}}
<references/>


[[Category:Neuroanatomy]]
[[Category:Brodmann areas]]
[[Category:Cerebral cortex]]
[[Category:Cerebral cortex]]
{{Neuroscience-stub}}
[[Category:Limbic system]]
<gallery>
File:Brodmann_area_33_animation_small.gif|Brodmann area 33 animation
File:Brodmann_area_33_medial.jpg|Brodmann area 33 medial view
</gallery>
<gallery>
File:Brodmann_Cytoarchitectonics_33.png|Brodmann area 33 cytoarchitectonics
File:Gray727-Brodman.png|Brodmann areas in the human brain
File:Brodmann_area_33_animation_small.gif|Brodmann area 33 animation
File:Brodmann_area_33_medial.jpg|Brodmann area 33 medial view
</gallery>

Latest revision as of 18:54, 23 March 2025

Brodmann area 33 is a subdivision of the cerebral cortex in the human brain.


Brodmann Area 33[edit]

Brodmann area 33 animation

Brodmann area 33 is a subdivision of the cerebral cortex in the human brain, defined based on its distinct cytoarchitecture. It is part of the cingulate cortex, which is involved in various functions including emotion formation and processing, learning, and memory.

Location[edit]

Brodmann area 33 is located in the medial aspect of the brain, within the cingulate gyrus. It is situated anteriorly to Brodmann area 24 and is considered a part of the limbic system. This area is found in the medial wall of the hemisphere, and it is often associated with the anterior cingulate cortex.

Cytoarchitecture[edit]

Brodmann area 33 cytoarchitectonics

The cytoarchitecture of Brodmann area 33 is characterized by a thin cortical layer with a relatively simple structure compared to other cortical areas. It is distinguished by its lack of a distinct layer IV, which is typical of the granular cortex. The neurons in this area are densely packed, and the area is involved in processing emotional and autonomic information.

Function[edit]

Brodmann area 33 is involved in the processing of emotional and autonomic responses. It plays a role in the regulation of emotional behavior, pain perception, and autonomic functions. The area is also implicated in the integration of cognitive and emotional information, contributing to the emotional regulation and decision-making processes.

Clinical Significance[edit]

Dysfunction in Brodmann area 33 has been associated with various neuropsychiatric disorders, including depression, anxiety disorders, and schizophrenia. Its role in emotional processing makes it a target for research in understanding the neural basis of these conditions.

Related Pages[edit]

Brodmann area 33 medial view

Template:Brodmann areas