Budesonide/glycopyrronium bromide/formoterol: Difference between revisions
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Latest revision as of 18:24, 18 March 2025
Budesonide/glycopyrronium bromide/formoterol (BGF) is a fixed-dose combination medication used in the management of chronic obstructive pulmonary disease (COPD). It contains three active ingredients: budesonide, a corticosteroid; glycopyrronium bromide, a long-acting muscarinic antagonist (LAMA); and formoterol, a long-acting beta2-adrenergic agonist (LABA).
Etymology[edit]
The name of the medication is derived from the names of its three active ingredients: budesonide, glycopyrronium bromide, and formoterol.
Pharmacology[edit]
Budesonide is a corticosteroid that reduces inflammation in the lungs. Glycopyrronium bromide is a muscarinic antagonist that dilates the airways, and formoterol is a beta2-adrenergic agonist that relaxes the muscles of the airways. Together, these three drugs help to improve breathing in people with COPD.
Indications[edit]
BGF is indicated for the maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and/or emphysema. It is also indicated to reduce exacerbations of COPD in patients with a history of exacerbations.
Contraindications[edit]
BGF is contraindicated in patients with a hypersensitivity to budesonide, glycopyrronium bromide, formoterol, or any of the ingredients in the formulation. It is also contraindicated in patients with asthma without use of a long-term asthma control medication.
Side Effects[edit]
Common side effects of BGF include upper respiratory tract infection, pneumonia, bronchitis, oral candidiasis, back pain, and cough. Serious side effects may include worsening of COPD, pneumonia, and osteoporosis.
Interactions[edit]
BGF may interact with other drugs, including beta-blockers, diuretics, anticholinergics, and other bronchodilators. It is important to tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
