PNET

Primitive Neuroectodermal Tumors (PNET) are a family of neoplasms that originate from neuroectodermal cells. These tumors are typically found in children and young adults, and can occur anywhere in the body. The most common locations are the brain, spine, and bone.

Classification

PNETs are classified into two main types: central PNETs (cPNETs) and peripheral PNETs (pPNETs). cPNETs occur in the brain and spinal cord, while pPNETs occur in the bones and soft tissues.

Symptoms

The symptoms of PNETs depend on the location of the tumor. Brain tumors can cause headache, nausea, vomiting, and changes in behavior. Spinal cord tumors can cause pain, weakness, and numbness in the limbs. Bone tumors can cause pain and swelling.

Diagnosis

Diagnosis of PNETs is based on imaging studies, biopsy, and histopathology. Imaging studies such as MRI and CT scan can show the location and size of the tumor. Biopsy involves taking a small sample of the tumor for examination under a microscope. Histopathology can confirm the diagnosis and determine the type of PNET.

Treatment

Treatment for PNETs typically involves a combination of surgery, radiation therapy, and chemotherapy. The goal of treatment is to remove or shrink the tumor, relieve symptoms, and improve quality of life.

Prognosis

The prognosis for PNETs varies depending on the type and location of the tumor, the patient's age and overall health, and the effectiveness of treatment. Some PNETs are curable with aggressive treatment, while others are more difficult to control.

See also

• Neuroectodermal tumor
• Ewing's sarcoma
• Neuroblastoma
• Medulloblastoma

References

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