MEAI: Difference between revisions

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{{Short description|Chemical compound}}
== MEAI ==
{{Drugbox
| verifiedfields = changed
| verifiedrevid = 477002123
| IUPAC_name = 5-Methoxy-2,3-dihydro-1H-inden-2-amine
| image = 5-Methoxy-2-indanamine.svg
| image_size = 200px
| image_alt = Skeletal formula of 5-Methoxy-2-indanamine
| width =
| alt =
| image2 =
| width2 =
| alt2 =
| tradename =
| synonyms = MEAI
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number = 13078-14-3
| ATC_prefix =
| ATC_suffix =
| PubChem = 443590
| ChemSpiderID = 391688
| UNII =
| KEGG =
| ChEBI =
| ChEMBL = 2105760
| C=10
| H=13
| N=1
| O=1
| smiles = COc1ccc2c(c1)CC(N)C2
| StdInChI = 1S/C10H13NO/c1-12-9-4-2-3-7-5-8(11)6-10(7)9/h2-4,8H,5-6,11H2,1H3
| StdInChIKey = ZJQJHNSJXWQKQF-UHFFFAOYSA-N
}}


'''MEAI''' (5-Methoxy-2-aminoindane) is a chemical compound that belongs to the class of [[aminoindanes]]. It is a psychoactive substance that has been researched for its potential effects on [[alcohol consumption]] and [[addiction]].
[[File:5-Methoxy-2-indanamine.svg|thumb|right|Chemical structure of MEAI]]


==Chemical Structure and Properties==
'''MEAI''' (5-Methoxy-2-aminoindane) is a psychoactive substance that belongs to the class of [[amphetamine]] derivatives. It is known for its unique effects, which are distinct from other stimulants and entactogens. MEAI has been studied for its potential use in reducing alcohol consumption and as a novel psychoactive substance.
[[File:5-Methoxy-2-indanamine.svg|Chemical structure of MEAI|thumb|right]]
MEAI is structurally related to other aminoindanes, characterized by a methoxy group at the 5-position of the indane ring. The compound has a molecular formula of C<sub>10</sub>H<sub>13</sub>NO and a molecular weight of 163.22 g/mol. The presence of the methoxy group is thought to influence its pharmacological activity.


==Pharmacology==
== Chemical Structure and Properties ==
MEAI acts as a [[serotonin receptor]] modulator, which may contribute to its psychoactive effects. It is believed to interact with the [[5-HT2A receptor]], a common target for many psychedelic substances. The exact mechanism of action is not fully understood, but it is hypothesized that MEAI may alter serotonin levels in the brain, leading to changes in mood and perception.


==Potential Applications==
MEAI is chemically related to the [[amphetamine]] family, characterized by the presence of a methoxy group at the 5-position of the indane ring. The chemical structure of MEAI is similar to that of other [[substituted amphetamines]], but it features an indane backbone instead of the typical phenethylamine structure. This modification is believed to contribute to its unique pharmacological profile.
Research into MEAI has primarily focused on its potential use in reducing alcohol consumption. Preliminary studies suggest that MEAI may help decrease the desire to consume alcohol, making it a candidate for further investigation as a treatment for [[alcohol use disorder]].


==Safety and Legal Status==
== Pharmacology ==
The safety profile of MEAI is not well-documented, and its legal status varies by country. As with many research chemicals, caution is advised due to the lack of comprehensive studies on its long-term effects and potential toxicity.


==Related Compounds==
The pharmacological effects of MEAI are not fully understood, but it is thought to act as a [[serotonin]] and [[dopamine]] releasing agent. Unlike traditional stimulants, MEAI is reported to produce a calming effect, which may be beneficial in reducing [[alcohol consumption]]. This effect is hypothesized to be due to its action on the [[serotonin receptor]]s, which play a role in mood regulation and impulse control.
MEAI is related to other compounds in the aminoindane family, such as [[2-Aminoindane]] and [[MDAI]]. These compounds share similar structural features and have been studied for their psychoactive properties.


==Related Pages==
== Potential Uses ==
* [[Aminoindane]]
 
* [[Serotonin receptor]]
MEAI has been investigated for its potential use in treating [[alcohol use disorder]]. Preliminary studies suggest that MEAI may help reduce the desire to consume alcohol by modulating the reward pathways in the brain. This makes it a candidate for further research in the development of treatments for [[substance use disorders]].
 
== Legal Status ==
 
The legal status of MEAI varies by country. In some jurisdictions, it is classified as a controlled substance due to its psychoactive properties, while in others, it remains unregulated. Researchers and policymakers continue to evaluate its safety and potential therapeutic benefits.
 
== Safety and Side Effects ==
 
As with many novel psychoactive substances, the safety profile of MEAI is not well-established. Users have reported both positive and negative effects, including mood enhancement and relaxation, as well as potential side effects such as anxiety and insomnia. Further research is needed to fully understand the risks associated with its use.
 
== Related Pages ==
 
* [[Amphetamine]]
* [[Serotonin]]
* [[Dopamine]]
* [[Alcohol use disorder]]
* [[Alcohol use disorder]]
* [[Substituted amphetamines]]


[[Category:Aminoindanes]]
[[Category:Psychoactive drugs]]
[[Category:Psychoactive drugs]]
[[Category:Serotonin receptor modulators]]
[[Category:Amphetamines]]
[[Category:Serotonin releasing agents]]

Latest revision as of 17:12, 5 March 2025

MEAI[edit]

Chemical structure of MEAI

MEAI (5-Methoxy-2-aminoindane) is a psychoactive substance that belongs to the class of amphetamine derivatives. It is known for its unique effects, which are distinct from other stimulants and entactogens. MEAI has been studied for its potential use in reducing alcohol consumption and as a novel psychoactive substance.

Chemical Structure and Properties[edit]

MEAI is chemically related to the amphetamine family, characterized by the presence of a methoxy group at the 5-position of the indane ring. The chemical structure of MEAI is similar to that of other substituted amphetamines, but it features an indane backbone instead of the typical phenethylamine structure. This modification is believed to contribute to its unique pharmacological profile.

Pharmacology[edit]

The pharmacological effects of MEAI are not fully understood, but it is thought to act as a serotonin and dopamine releasing agent. Unlike traditional stimulants, MEAI is reported to produce a calming effect, which may be beneficial in reducing alcohol consumption. This effect is hypothesized to be due to its action on the serotonin receptors, which play a role in mood regulation and impulse control.

Potential Uses[edit]

MEAI has been investigated for its potential use in treating alcohol use disorder. Preliminary studies suggest that MEAI may help reduce the desire to consume alcohol by modulating the reward pathways in the brain. This makes it a candidate for further research in the development of treatments for substance use disorders.

Legal Status[edit]

The legal status of MEAI varies by country. In some jurisdictions, it is classified as a controlled substance due to its psychoactive properties, while in others, it remains unregulated. Researchers and policymakers continue to evaluate its safety and potential therapeutic benefits.

Safety and Side Effects[edit]

As with many novel psychoactive substances, the safety profile of MEAI is not well-established. Users have reported both positive and negative effects, including mood enhancement and relaxation, as well as potential side effects such as anxiety and insomnia. Further research is needed to fully understand the risks associated with its use.

Related Pages[edit]