Fenoterol: Difference between revisions
CSV import Tags: mobile edit mobile web edit |
CSV import |
||
| Line 1: | Line 1: | ||
= Fenoterol = | |||
[[File:(RR)-_and_(SS)-_fenoterol.svg|thumb|right|Chemical structure of (RR)- and (SS)-fenoterol]] | |||
'''Fenoterol''' is a [[bronchodilator]] used in the management of [[asthma]] and other conditions associated with [[bronchospasm]]. It is a [[beta-2 adrenergic receptor]] agonist that works by relaxing the muscles in the airways and increasing airflow to the lungs. | |||
Fenoterol | |||
== | == Pharmacology == | ||
Fenoterol is a selective [[beta-2 adrenergic receptor]] agonist. It binds to these receptors in the [[bronchial smooth muscle]], leading to muscle relaxation and bronchodilation. This action helps to relieve symptoms of [[bronchospasm]] such as wheezing, coughing, and shortness of breath. | |||
== Stereochemistry == | |||
[[File:Fenoterol_stereoisomers.svg|thumb|left|Stereoisomers of fenoterol]] | |||
Fenoterol has two chiral centers, resulting in four possible stereoisomers. The (R,R)- and (S,S)-enantiomers are the most relevant in terms of pharmacological activity. The (R,R)-enantiomer is primarily responsible for the bronchodilatory effects, while the (S,S)-enantiomer is less active. | |||
== Clinical Use == | |||
Fenoterol is commonly used in the treatment of [[asthma]] and [[chronic obstructive pulmonary disease]] (COPD). It is often administered via [[inhalation]] to provide rapid relief from acute bronchospasm. Fenoterol is available in various formulations, including metered-dose inhalers and nebulizer solutions. | |||
== Side Effects == | |||
Common side effects of fenoterol include [[tremor]], [[tachycardia]], and [[nervousness]]. These effects are generally mild and transient. However, excessive use of fenoterol can lead to more serious cardiovascular effects, such as [[arrhythmias]] and [[hypertension]]. | |||
== | == History == | ||
Fenoterol was developed in the 1960s and has been used clinically since the 1970s. It was marketed under various brand names, including Berotec. | |||
[[File:Berotec.jpg|thumb|right|A Berotec inhaler containing fenoterol]] | |||
[[File: | |||
== Related Pages == | |||
* [[Asthma]] | * [[Asthma]] | ||
* [[Chronic obstructive pulmonary disease]] | * [[Chronic obstructive pulmonary disease]] | ||
| Line 52: | Line 36: | ||
* [[Bronchodilator]] | * [[Bronchodilator]] | ||
{{Bronchodilators}} | |||
[[Category:Beta-2 adrenergic agonists]] | |||
[[Category:Bronchodilators]] | [[Category:Bronchodilators]] | ||
Latest revision as of 14:18, 21 February 2025
Fenoterol[edit]
-_and_(SS)-_fenoterol.svg)
Fenoterol is a bronchodilator used in the management of asthma and other conditions associated with bronchospasm. It is a beta-2 adrenergic receptor agonist that works by relaxing the muscles in the airways and increasing airflow to the lungs.
Pharmacology[edit]
Fenoterol is a selective beta-2 adrenergic receptor agonist. It binds to these receptors in the bronchial smooth muscle, leading to muscle relaxation and bronchodilation. This action helps to relieve symptoms of bronchospasm such as wheezing, coughing, and shortness of breath.
Stereochemistry[edit]
Fenoterol has two chiral centers, resulting in four possible stereoisomers. The (R,R)- and (S,S)-enantiomers are the most relevant in terms of pharmacological activity. The (R,R)-enantiomer is primarily responsible for the bronchodilatory effects, while the (S,S)-enantiomer is less active.
Clinical Use[edit]
Fenoterol is commonly used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). It is often administered via inhalation to provide rapid relief from acute bronchospasm. Fenoterol is available in various formulations, including metered-dose inhalers and nebulizer solutions.
Side Effects[edit]
Common side effects of fenoterol include tremor, tachycardia, and nervousness. These effects are generally mild and transient. However, excessive use of fenoterol can lead to more serious cardiovascular effects, such as arrhythmias and hypertension.
History[edit]
Fenoterol was developed in the 1960s and has been used clinically since the 1970s. It was marketed under various brand names, including Berotec.
