Meckel's diverticulum: Difference between revisions

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'''Meckel's diverticulum''' is a congenital malformation of the gastrointestinal tract. It is a true diverticulum, meaning it is composed of all three layers of the bowel wall, and is a remnant of the omphalomesenteric duct (also known as the vitelline duct or yolk stalk). It is the most common congenital malformation of the gastrointestinal tract and is present in approximately 2% of the population.
{{Short description|Congenital anomaly of the gastrointestinal tract}}
{{Use dmy dates|date=October 2023}}


== Anatomy ==
'''Meckel's diverticulum''' is a congenital anomaly of the [[gastrointestinal tract]] that results from an incomplete obliteration of the [[vitelline duct]] (also known as the omphalomesenteric duct) during embryonic development. It is the most common congenital defect of the gastrointestinal tract, occurring in approximately 2% of the population.
Meckel's diverticulum is located on the anti-mesenteric border of the ileum, approximately 2 feet proximal to the ileocecal valve. The size of the diverticulum varies, but it is typically 2 inches long and 2 cm in diameter. The diverticulum may contain ectopic tissue, most commonly gastric and pancreatic.


== Pathophysiology ==
==Anatomy and Pathophysiology==
The pathophysiology of Meckel's diverticulum is related to its potential to develop complications. These include bleeding, obstruction, inflammation, and perforation. Bleeding is the most common complication in children and is due to the presence of ectopic gastric mucosa, which secretes acid that can cause ulceration of the adjacent ileal mucosa. Obstruction is the most common complication in adults and can occur due to intussusception, volvulus, or a band of adhesions.
[[File:Diverticule_de_Meckel.jpg|thumb|right|Illustration of Meckel's diverticulum]]
Meckel's diverticulum is a true diverticulum, meaning it contains all layers of the intestinal wall, including the mucosa, submucosa, and muscularis propria. It is typically located in the [[ileum]], about 40 to 100 cm proximal to the [[ileocecal valve]]. The diverticulum is usually 3 to 5 cm in length, but it can vary significantly.


== Clinical presentation ==
The presence of ectopic tissue, such as [[gastric mucosa]] or [[pancreatic tissue]], within the diverticulum can lead to complications. Gastric mucosa can secrete acid, leading to [[ulceration]] and [[bleeding]].
The clinical presentation of Meckel's diverticulum is variable and depends on the age of the patient and the type of complication. In children, the most common presentation is painless rectal bleeding, which can be massive. In adults, the most common presentation is intestinal obstruction, which can manifest as abdominal pain, vomiting, and constipation.


== Diagnosis ==
==Clinical Presentation==
The diagnosis of Meckel's diverticulum can be challenging due to its variable presentation and the lack of specific symptoms. The gold standard for diagnosis is technetium-99m pertechnetate scintigraphy (Meckel's scan), which detects the ectopic gastric mucosa. Other diagnostic modalities include ultrasound, computed tomography, and magnetic resonance imaging.
[[File:Meckel's_Diverticulum_AFIP.jpg|thumb|left|Pathological specimen of Meckel's diverticulum]]
Most individuals with Meckel's diverticulum are asymptomatic. However, when symptoms do occur, they often present in childhood. The classic presentation includes painless rectal bleeding, which may be due to ulceration of the ectopic gastric mucosa.


== Treatment ==
Other potential complications include [[intestinal obstruction]], [[volvulus]], and [[intussusception]]. Inflammation of the diverticulum, known as Meckel's diverticulitis, can mimic [[appendicitis]].
The treatment of Meckel's diverticulum depends on the presence and type of complications. Asymptomatic diverticula in adults are typically managed conservatively, while symptomatic diverticula and all diverticula in children are usually treated surgically. The surgical options include diverticulectomy, segmental resection, and laparoscopic surgery.


== See also ==
==Diagnosis==
* [[Gastrointestinal tract]]
[[File:Meckel's_Diverticulum_by_Technetium-99m_Pertechnetate_Scan.jpg|thumb|right|Meckel's diverticulum as seen on a technetium-99m pertechnetate scan]]
* [[Congenital disorders]]
The diagnosis of Meckel's diverticulum can be challenging, especially in asymptomatic individuals. When symptomatic, a [[technetium-99m pertechnetate scan]] (Meckel's scan) is often used to detect ectopic gastric mucosa. This scan is particularly useful in children presenting with unexplained gastrointestinal bleeding.
* [[Diverticulum]]
 
Other diagnostic modalities include [[CT scan]], [[MRI]], and [[endoscopy]], although these are less specific.
 
==Treatment==
[[File:Cck1.png|thumb|left|Surgical resection of Meckel's diverticulum]]
The treatment of Meckel's diverticulum depends on the presence and type of symptoms. Asymptomatic diverticula are often left untreated. However, symptomatic diverticula, especially those causing bleeding or obstruction, typically require surgical intervention.
 
Surgical options include diverticulectomy, where only the diverticulum is removed, or segmental resection, where a portion of the ileum is removed along with the diverticulum.
 
==Prognosis==
The prognosis for individuals with Meckel's diverticulum is generally excellent, especially when complications are promptly addressed. Surgical treatment of symptomatic diverticula usually results in complete resolution of symptoms.
 
==Related pages==
* [[Appendicitis]]
* [[Intestinal obstruction]]
* [[Intestinal obstruction]]
* [[Rectal bleeding]]
* [[Gastrointestinal bleeding]]
 
[[Category:Gastrointestinal tract disorders]]
[[Category:Congenital disorders]]
[[Category:Medical terminology]]


{{stub}}
[[Category:Congenital disorders of digestive system]]
<gallery>
[[Category:Gastroenterology]]
File:Diverticule de Meckel.jpg|Meckel's diverticulum
File:Meckel's Diverticulum AFIP.jpg|Meckel's diverticulum
File:Cck1.png|Meckel's diverticulum
File:Cck2.png|Meckel's diverticulum
File:Ocystck.png|Meckel's diverticulum
File:Cck3.png|Meckel's diverticulum
File:MCck7b.jpg|Meckel's diverticulum
File:Meckel's Diverticulum by Technetium-99m Pertechnetate Scan.jpg|Meckel's diverticulum
File:Angiography of a Meckel's diverticulum that presented with bleeding.jpg|Meckel's diverticulum
</gallery>

Revision as of 14:14, 21 February 2025

Congenital anomaly of the gastrointestinal tract



Meckel's diverticulum is a congenital anomaly of the gastrointestinal tract that results from an incomplete obliteration of the vitelline duct (also known as the omphalomesenteric duct) during embryonic development. It is the most common congenital defect of the gastrointestinal tract, occurring in approximately 2% of the population.

Anatomy and Pathophysiology

File:Diverticule de Meckel.jpg
Illustration of Meckel's diverticulum

Meckel's diverticulum is a true diverticulum, meaning it contains all layers of the intestinal wall, including the mucosa, submucosa, and muscularis propria. It is typically located in the ileum, about 40 to 100 cm proximal to the ileocecal valve. The diverticulum is usually 3 to 5 cm in length, but it can vary significantly.

The presence of ectopic tissue, such as gastric mucosa or pancreatic tissue, within the diverticulum can lead to complications. Gastric mucosa can secrete acid, leading to ulceration and bleeding.

Clinical Presentation

File:Meckel's Diverticulum AFIP.jpg
Pathological specimen of Meckel's diverticulum

Most individuals with Meckel's diverticulum are asymptomatic. However, when symptoms do occur, they often present in childhood. The classic presentation includes painless rectal bleeding, which may be due to ulceration of the ectopic gastric mucosa.

Other potential complications include intestinal obstruction, volvulus, and intussusception. Inflammation of the diverticulum, known as Meckel's diverticulitis, can mimic appendicitis.

Diagnosis

File:Meckel's Diverticulum by Technetium-99m Pertechnetate Scan.jpg
Meckel's diverticulum as seen on a technetium-99m pertechnetate scan

The diagnosis of Meckel's diverticulum can be challenging, especially in asymptomatic individuals. When symptomatic, a technetium-99m pertechnetate scan (Meckel's scan) is often used to detect ectopic gastric mucosa. This scan is particularly useful in children presenting with unexplained gastrointestinal bleeding.

Other diagnostic modalities include CT scan, MRI, and endoscopy, although these are less specific.

Treatment

File:Cck1.png
Surgical resection of Meckel's diverticulum

The treatment of Meckel's diverticulum depends on the presence and type of symptoms. Asymptomatic diverticula are often left untreated. However, symptomatic diverticula, especially those causing bleeding or obstruction, typically require surgical intervention.

Surgical options include diverticulectomy, where only the diverticulum is removed, or segmental resection, where a portion of the ileum is removed along with the diverticulum.

Prognosis

The prognosis for individuals with Meckel's diverticulum is generally excellent, especially when complications are promptly addressed. Surgical treatment of symptomatic diverticula usually results in complete resolution of symptoms.

Related pages