Muscimol: Difference between revisions

Revision as of 01:08, 20 February 2025

Muscimol is a naturally occurring psychoactive and hallucinogenic compound found in certain species of mushrooms, particularly those in the Amanita genus. It is a potent GABA_A agonist, which means it can produce a range of effects from mild euphoria to powerful hallucinations.

Chemical Structure and Properties

Muscimol is a heterocyclic amine with a five-membered ring structure. It is soluble in water and can be extracted from mushrooms using a simple water extraction. The compound is stable under normal conditions, but can degrade if exposed to strong acids or bases.

Pharmacology

Muscimol acts as a potent agonist at GABA_A receptors, which are widely distributed throughout the brain. This action leads to an increase in inhibitory neurotransmission, which can result in a range of effects depending on the dose and individual susceptibility. These effects can include relaxation, euphoria, and in higher doses, hallucinations.

Toxicity

While muscimol is not considered lethal in normal doses, it can cause a range of unpleasant side effects, including nausea, vomiting, and in severe cases, seizures. It is also known to be habit-forming, with withdrawal symptoms including anxiety and insomnia.

Legal Status

Muscimol is not currently controlled under the United Nations Convention on Psychotropic Substances, but it may be illegal in some countries under national law. In the United States, it is not controlled under the Controlled Substances Act, but it may be considered illegal under the Federal Analogue Act if intended for human consumption.

Muscimol

Muscimol chemical structure
Muscimol 3D
Muscimol structure ball and stick
Amanita muscaria
Muscimol vs GABA 3D
Step 1 Gagneux
Step 2 Gagneux
McCarry Synthesis
Varasi Synthesis
Varasi Part 2 Synthesis

@@ Line 31: / Line 31: @@
 File:Varasi Synthesis New Nums.png|Muscimol
 File:Varasi Part 2 Synthesis New Nums Fixed.png|Muscimol
+</gallery>
+== Muscimol ==
+<gallery>
+File:Muscimol chemical structure.svg|Muscimol chemical structure
+File:Muscimol3d.png|Muscimol 3D
+File:Muscimol structure ball and stick.png|Muscimol structure ball and stick
+File:Amanita muscaria 3 vliegenzwammen op rij.jpg|Amanita muscaria
+File:Muscimol vs GABA 3D.png|Muscimol vs GABA 3D
+File:Step 1 Gagneux.png|Step 1 Gagneux
+File:Step 2 Gagneux.png|Step 2 Gagneux
+File:McCarry Synthesis New Nums.png|McCarry Synthesis
+File:Varasi Synthesis New Nums.png|Varasi Synthesis
+File:Varasi Part 2 Synthesis New Nums Fixed.png|Varasi Part 2 Synthesis
 </gallery>