8-Carboxamidocyclazocine: Difference between revisions
CSV import |
CSV import |
||
| Line 29: | Line 29: | ||
[[Category:Opioids]] | [[Category:Opioids]] | ||
[[Category:Kappa-opioid receptor agonists]] | [[Category:Kappa-opioid receptor agonists]] | ||
<gallery> | |||
File:8-Carboxamidocyclazocine.svg|8-Carboxamidocyclazocine | |||
</gallery> | |||
Latest revision as of 22:13, 16 February 2025
A chemical compound related to cyclazocine
| Chemical Compound | |
|---|---|
| Identifiers | |
| CAS Number | |
| PubChem CID | |
| ChemSpider ID | |
| UNII | |
| ChEBI | |
| ChEMBL | |
| Properties | |
| Chemical Formula | |
| Molar Mass | |
| Appearance | |
| Density | |
| Melting Point | |
| Boiling Point | |
| Hazards | |
| GHS Pictograms | [[File:|50px]] |
| GHS Signal Word | |
| GHS Hazard Statements | |
| NFPA 704 | [[File:|50px]] |
| References | |
8-Carboxamidocyclazocine is a chemical compound that belongs to the class of benzomorphan opioids. It is structurally related to cyclazocine, a well-known opioid receptor agonist and antagonist.
Chemical structure and properties[edit]
8-Carboxamidocyclazocine is a derivative of cyclazocine, characterized by the presence of a carboxamide group at the 8-position of the benzomorphan skeleton. This modification alters its binding affinity and activity at various opioid receptors.
Pharmacology[edit]
8-Carboxamidocyclazocine acts as a kappa-opioid receptor agonist and a mu-opioid receptor partial agonist. The kappa-opioid receptor activity is associated with its potential analgesic effects, as well as its ability to produce dysphoria and hallucinations in some cases. The mu-opioid receptor activity contributes to its analgesic properties but also limits its use due to potential for abuse and dependence.
Potential therapeutic uses[edit]
Research into 8-Carboxamidocyclazocine has focused on its potential as an analgesic with reduced abuse potential compared to traditional mu-opioid receptor agonists. Its kappa-opioid receptor activity may also make it useful in treating conditions such as depression and anxiety, although these applications are still under investigation.
Side effects and safety[edit]
As with other kappa-opioid receptor agonists, 8-Carboxamidocyclazocine may cause side effects such as dysphoria, hallucinations, and sedation. Its safety profile is not fully established, and further research is needed to determine its long-term effects and potential for abuse.
Related pages[edit]
-
8-Carboxamidocyclazocine
