Optic disc drusen

Optic disc drusen (ODD) are globules of protein and calcium salts that accumulate in the optic nerve, particularly in the anterior portion. They are generally benign and are often discovered incidentally during routine eye examinations. However, in some cases, they can lead to visual field defects or other complications.

Etiology

The exact cause of optic disc drusen is unknown. They are thought to result from abnormal metabolism of retinal ganglion cells, which leads to the accumulation of waste products in the optic nerve. Some studies suggest a genetic component, as ODD has been found to occur more frequently in certain families.

Clinical Presentation

Patients with optic disc drusen are often asymptomatic. When symptoms do occur, they may include visual field defects, transient visual obscurations, and, rarely, visual loss. The drusen themselves are typically visible as yellowish refractile bodies on the surface of the optic disc.

Diagnosis

Diagnosis of optic disc drusen is typically made through ophthalmoscopic examination. Additional diagnostic tests may include fluorescein angiography, optical coherence tomography (OCT), and visual field testing. In some cases, ultrasound may be used to confirm the diagnosis.

Treatment and Prognosis

There is currently no cure for optic disc drusen. Treatment is generally aimed at managing any associated symptoms and monitoring for potential complications. Regular eye examinations are recommended for individuals with ODD to monitor for changes in vision or the development of complications such as neovascularization or optic nerve compression.

See Also

• Optic nerve
• Visual field test
• Fluorescein angiography
• Optical coherence tomography

References

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Optic disc drusen

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