18-Methyltestosterone: Difference between revisions
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== 18-Methyltestosterone == | |||
[[File:18-Methyltestosterone.svg|thumb|right|Chemical structure of 18-Methyltestosterone]] | |||
'''18-Methyltestosterone''' is a synthetic [[androgen]] and [[anabolic steroid]] (AAS) that is used in the treatment of male [[hypogonadism]], delayed puberty in boys, and in low doses as a component of hormone therapy for [[transgender men]]. It is also used in the treatment of [[breast cancer]] in women, though this use is less common. | |||
18-Methyltestosterone is a [[ | |||
== | == Chemical Properties == | ||
18-Methyltestosterone is a derivative of [[testosterone]], the primary male sex hormone and an anabolic steroid. It is characterized by the addition of a methyl group at the 18th carbon position of the steroid structure, which distinguishes it from testosterone. This modification enhances its oral bioavailability and makes it more resistant to metabolic degradation. | |||
18-Methyltestosterone | |||
== | == Mechanism of Action == | ||
== | As an androgen, 18-Methyltestosterone binds to the [[androgen receptor]] in target tissues. This binding activates the receptor, leading to changes in gene expression that result in the development and maintenance of male secondary sexual characteristics and anabolic effects such as increased muscle mass and strength. | ||
== Medical Uses == | |||
18-Methyltestosterone is primarily used in the treatment of conditions associated with low testosterone levels. These include: | |||
* [[Hypogonadism]] in males, where the body does not produce enough testosterone. | |||
* Delayed puberty in boys, to stimulate the development of secondary sexual characteristics. | |||
* As part of hormone therapy for transgender men, to induce masculinization. | |||
* Occasionally, in the treatment of breast cancer in women, due to its anti-estrogenic effects. | |||
== Side Effects == | |||
The use of 18-Methyltestosterone can lead to a range of side effects, particularly when used in high doses or for extended periods. Common side effects include: | |||
* [[Acne]] | |||
* Increased body hair growth | |||
* [[Gynecomastia]] | |||
* [[Liver toxicity]] | |||
* Changes in mood and behavior | |||
== Related Pages == | |||
* [[Testosterone]] | * [[Testosterone]] | ||
* [[Anabolic steroid]] | * [[Anabolic steroid]] | ||
* [[Androgen receptor]] | * [[Androgen receptor]] | ||
* [[ | * [[Hypogonadism]] | ||
* [[Breast cancer]] | |||
[[Category:Androgens and anabolic steroids]] | [[Category:Androgens and anabolic steroids]] | ||
[[Category: | [[Category:Hormones]] | ||
[[Category:Endocrinology]] | |||
Latest revision as of 05:27, 16 February 2025
18-Methyltestosterone[edit]
18-Methyltestosterone is a synthetic androgen and anabolic steroid (AAS) that is used in the treatment of male hypogonadism, delayed puberty in boys, and in low doses as a component of hormone therapy for transgender men. It is also used in the treatment of breast cancer in women, though this use is less common.
Chemical Properties[edit]
18-Methyltestosterone is a derivative of testosterone, the primary male sex hormone and an anabolic steroid. It is characterized by the addition of a methyl group at the 18th carbon position of the steroid structure, which distinguishes it from testosterone. This modification enhances its oral bioavailability and makes it more resistant to metabolic degradation.
Mechanism of Action[edit]
As an androgen, 18-Methyltestosterone binds to the androgen receptor in target tissues. This binding activates the receptor, leading to changes in gene expression that result in the development and maintenance of male secondary sexual characteristics and anabolic effects such as increased muscle mass and strength.
Medical Uses[edit]
18-Methyltestosterone is primarily used in the treatment of conditions associated with low testosterone levels. These include:
- Hypogonadism in males, where the body does not produce enough testosterone.
- Delayed puberty in boys, to stimulate the development of secondary sexual characteristics.
- As part of hormone therapy for transgender men, to induce masculinization.
- Occasionally, in the treatment of breast cancer in women, due to its anti-estrogenic effects.
Side Effects[edit]
The use of 18-Methyltestosterone can lead to a range of side effects, particularly when used in high doses or for extended periods. Common side effects include:
- Acne
- Increased body hair growth
- Gynecomastia
- Liver toxicity
- Changes in mood and behavior
