Methyl-1-testosterone: Difference between revisions
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{{DISPLAYTITLE:Methyl-1-testosterone}} | |||
== | == Methyl-1-testosterone == | ||
[[File:Methyl-1-testosterone.svg|thumb|right|Chemical structure of Methyl-1-testosterone]] | |||
'''Methyl-1-testosterone''' (M1T) is a synthetic [[anabolic steroid]] that was first developed in the 1960s. It is a derivative of [[testosterone]], modified to enhance its anabolic properties while reducing its androgenic effects. M1T is known for its potent muscle-building effects and has been used by athletes and bodybuilders to increase muscle mass and strength. | |||
Methyl-1-testosterone | == Chemical Structure and Properties == | ||
Methyl-1-testosterone is chemically known as 17_-methyl-17_-hydroxy-5_-androst-1-en-3-one. The addition of a methyl group at the 17th carbon position of the steroid structure increases its oral bioavailability, allowing it to be effective when taken orally. This modification also contributes to its hepatotoxicity, a common side effect associated with oral anabolic steroids. | |||
== | == Mechanism of Action == | ||
M1T exerts its effects by binding to the [[androgen receptor]] in muscle and bone tissues, promoting protein synthesis and muscle growth. It also influences the expression of genes involved in muscle hypertrophy and strength. The anabolic effects of M1T are significantly greater than those of testosterone, making it a popular choice for those seeking rapid gains in muscle mass. | |||
== Side Effects == | == Side Effects == | ||
The use of Methyl-1-testosterone is associated with several side effects, primarily due to its potent androgenic activity and liver toxicity. Common side effects include: | |||
The use of Methyl-1-testosterone | * [[Hepatotoxicity]]: M1T can cause liver damage, especially with prolonged use or high doses. | ||
* [[Androgenic effects]]: These include acne, hair loss, and increased body hair growth. | |||
* [[Cardiovascular effects]]: M1T can negatively impact cholesterol levels, increasing the risk of cardiovascular disease. | |||
* [[Endocrine disruption]]: It can suppress natural testosterone production, leading to hypogonadism. | |||
== Legal Status == | == Legal Status == | ||
Methyl-1-testosterone is classified as a controlled substance in many countries due to its potential for abuse and health risks. In the United States, it is listed as a Schedule III controlled substance under the [[Anabolic Steroid Control Act]]. | |||
== Use in Sports == | |||
M1T has been banned by most major sporting organizations, including the [[World Anti-Doping Agency]] (WADA), due to its performance-enhancing effects. Athletes found using M1T face penalties, including suspension and disqualification from competitions. | |||
== Related Pages == | |||
* [[Anabolic steroid]] | * [[Anabolic steroid]] | ||
* [[Testosterone]] | * [[Testosterone]] | ||
* [[Androgen receptor]] | |||
* [[Hepatotoxicity]] | |||
[[Category:Anabolic steroids]] | [[Category:Anabolic steroids]] | ||
[[Category:Androgens]] | [[Category:Androgens and anabolic steroids]] | ||
Latest revision as of 05:20, 16 February 2025
Methyl-1-testosterone[edit]
Methyl-1-testosterone (M1T) is a synthetic anabolic steroid that was first developed in the 1960s. It is a derivative of testosterone, modified to enhance its anabolic properties while reducing its androgenic effects. M1T is known for its potent muscle-building effects and has been used by athletes and bodybuilders to increase muscle mass and strength.
Chemical Structure and Properties[edit]
Methyl-1-testosterone is chemically known as 17_-methyl-17_-hydroxy-5_-androst-1-en-3-one. The addition of a methyl group at the 17th carbon position of the steroid structure increases its oral bioavailability, allowing it to be effective when taken orally. This modification also contributes to its hepatotoxicity, a common side effect associated with oral anabolic steroids.
Mechanism of Action[edit]
M1T exerts its effects by binding to the androgen receptor in muscle and bone tissues, promoting protein synthesis and muscle growth. It also influences the expression of genes involved in muscle hypertrophy and strength. The anabolic effects of M1T are significantly greater than those of testosterone, making it a popular choice for those seeking rapid gains in muscle mass.
Side Effects[edit]
The use of Methyl-1-testosterone is associated with several side effects, primarily due to its potent androgenic activity and liver toxicity. Common side effects include:
- Hepatotoxicity: M1T can cause liver damage, especially with prolonged use or high doses.
- Androgenic effects: These include acne, hair loss, and increased body hair growth.
- Cardiovascular effects: M1T can negatively impact cholesterol levels, increasing the risk of cardiovascular disease.
- Endocrine disruption: It can suppress natural testosterone production, leading to hypogonadism.
Legal Status[edit]
Methyl-1-testosterone is classified as a controlled substance in many countries due to its potential for abuse and health risks. In the United States, it is listed as a Schedule III controlled substance under the Anabolic Steroid Control Act.
Use in Sports[edit]
M1T has been banned by most major sporting organizations, including the World Anti-Doping Agency (WADA), due to its performance-enhancing effects. Athletes found using M1T face penalties, including suspension and disqualification from competitions.
