Proxibarbital: Difference between revisions
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'''Proxibarbital''' is a [[barbiturate]] derivative that | == Proxibarbital == | ||
[[File:Proxibarbital.svg|thumb|right|Chemical structure of Proxibarbital]] | |||
'''Proxibarbital''' is a [[barbiturate]] derivative that has been used as a [[sedative]] and [[hypnotic]] agent. It is known for its [[central nervous system]] depressant effects, which are typical of barbiturates. Proxibarbital is less commonly used today due to the development of safer and more effective [[benzodiazepines]] and other [[sedative-hypnotic]] drugs. | |||
== Chemical Properties == | |||
Proxibarbital is a [[chemical compound]] with the molecular formula C<sub>13</sub>H<sub>18</sub>N<sub>2</sub>O<sub>3</sub>. It is a [[barbituric acid]] derivative, characterized by the presence of a [[pyrimidine]] ring structure. The chemical structure of proxibarbital includes a [[propyl]] group attached to the nitrogen atom, which influences its pharmacological properties. | |||
== Pharmacology == | == Pharmacology == | ||
Proxibarbital | Proxibarbital acts on the [[gamma-aminobutyric acid]] (GABA) [[receptor]] complex, enhancing the inhibitory effects of GABA in the [[brain]]. This action results in [[sedation]], [[anxiolysis]], and [[hypnosis]]. Like other barbiturates, proxibarbital can cause [[respiratory depression]] and [[coma]] in overdose situations. | ||
== | == Clinical Use == | ||
Historically, proxibarbital was prescribed for the treatment of [[insomnia]] and [[anxiety]]. However, due to its potential for [[dependence]] and [[abuse]], as well as the risk of [[overdose]], its use has declined. Modern [[medicine]] prefers [[benzodiazepines]] and other [[non-barbiturate]] sedatives for these indications. | |||
== Side Effects == | == Side Effects == | ||
Common side effects of proxibarbital include drowsiness, dizziness, and | Common side effects of proxibarbital include [[drowsiness]], [[dizziness]], and [[headache]]. More severe side effects can include [[confusion]], [[ataxia]], and [[respiratory depression]]. Long-term use can lead to [[tolerance]], [[dependence]], and [[withdrawal]] symptoms upon discontinuation. | ||
== | == Related Pages == | ||
* [[Barbiturate]] | * [[Barbiturate]] | ||
* [[Sedative]] | * [[Sedative]] | ||
* [[Hypnotic]] | |||
* [[Benzodiazepine]] | |||
* [[Central nervous system]] | |||
[[Category:Barbiturates]] | [[Category:Barbiturates]] | ||
[[Category:Sedatives]] | |||
[[Category:Hypnotics]] | |||
Latest revision as of 11:34, 15 February 2025
Proxibarbital[edit]
Proxibarbital is a barbiturate derivative that has been used as a sedative and hypnotic agent. It is known for its central nervous system depressant effects, which are typical of barbiturates. Proxibarbital is less commonly used today due to the development of safer and more effective benzodiazepines and other sedative-hypnotic drugs.
Chemical Properties[edit]
Proxibarbital is a chemical compound with the molecular formula C13H18N2O3. It is a barbituric acid derivative, characterized by the presence of a pyrimidine ring structure. The chemical structure of proxibarbital includes a propyl group attached to the nitrogen atom, which influences its pharmacological properties.
Pharmacology[edit]
Proxibarbital acts on the gamma-aminobutyric acid (GABA) receptor complex, enhancing the inhibitory effects of GABA in the brain. This action results in sedation, anxiolysis, and hypnosis. Like other barbiturates, proxibarbital can cause respiratory depression and coma in overdose situations.
Clinical Use[edit]
Historically, proxibarbital was prescribed for the treatment of insomnia and anxiety. However, due to its potential for dependence and abuse, as well as the risk of overdose, its use has declined. Modern medicine prefers benzodiazepines and other non-barbiturate sedatives for these indications.
Side Effects[edit]
Common side effects of proxibarbital include drowsiness, dizziness, and headache. More severe side effects can include confusion, ataxia, and respiratory depression. Long-term use can lead to tolerance, dependence, and withdrawal symptoms upon discontinuation.
