Chloroacetamide: Difference between revisions

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'''Chloroacetamide''' is an [[organic compound]] with the formula ClCH<sub>2</sub>CONH<sub>2</sub>. This white solid is a widely used [[preservative]] and [[antimicrobial]] agent that is used in a variety of applications, including [[cosmetics]], [[shampoo]], and [[skin care products]].
{{DISPLAYTITLE:Chloroacetamide}}


==Chemical Structure and Properties==
==Chloroacetamide==
Chloroacetamide is a derivative of [[acetic acid]], with a [[chlorine]] atom replacing one of the hydrogen atoms on the methyl group, and an [[amide]] group replacing the hydroxyl group. This gives it the ability to form [[hydrogen bonds]], which contributes to its antimicrobial properties. It is a white solid at room temperature, with a melting point of 119-121 °C.
[[File:2-chloroacetamide_200.svg|thumb|right|Structural formula of Chloroacetamide]]
'''Chloroacetamide''' is an organic compound with the chemical formula C<sub>2</sub>H<sub>4</sub>ClNO. It is a member of the class of compounds known as [[acetamides]], which are derivatives of [[acetic acid]] where the hydroxyl group is replaced by an amine group. Chloroacetamide is characterized by the presence of a chlorine atom attached to the acetamide moiety.


==Uses==
==Chemical Properties==
Chloroacetamide is primarily used as a preservative and antimicrobial agent. It is effective against a broad spectrum of [[microorganisms]], including [[bacteria]], [[yeasts]], and [[molds]]. This makes it a popular choice for use in personal care products, where it helps to prevent spoilage and extend shelf life.
Chloroacetamide is a white crystalline solid at room temperature. It is soluble in water and various organic solvents. The presence of the chlorine atom in its structure makes it a reactive compound, particularly in [[nucleophilic substitution reactions]].


In addition to its antimicrobial properties, chloroacetamide also has some [[antioxidant]] activity. This can help to protect products from oxidation, which can cause changes in color, odor, and texture.
==Synthesis==
Chloroacetamide can be synthesized through the reaction of [[chloroacetyl chloride]] with [[ammonia]] or an amine. The reaction typically involves the acylation of the amine group, resulting in the formation of the amide bond.


==Safety==
==Applications==
The safety of chloroacetamide has been extensively studied. It is generally considered safe for use in cosmetics and personal care products at concentrations up to 0.3%. However, it can cause [[skin irritation]] and [[allergic reactions]] in some individuals, particularly at higher concentrations. For this reason, it is recommended to perform a patch test before using products containing chloroacetamide for the first time.
Chloroacetamide is used in various industrial applications, primarily as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It serves as a building block for the production of more complex chemical compounds.


==See Also==
==Toxicity and Safety==
* [[Preservative]]
Chloroacetamide is known to be toxic and should be handled with care. It can cause irritation to the skin, eyes, and respiratory tract. Proper safety measures, including the use of personal protective equipment, should be employed when handling this compound.
* [[Antimicrobial]]
 
* [[Cosmetics]]
==Related Compounds==
* [[Skin care]]
* [[Acetamide]]
* [[Chloroacetic acid]]
* [[Chloroacetyl chloride]]
 
==Related pages==
* [[Organic chemistry]]
* [[Chemical synthesis]]
* [[Industrial chemistry]]


[[Category:Organic compounds]]
[[Category:Organic compounds]]
[[Category:Preservatives]]
[[Category:Amides]]
[[Category:Antimicrobials]]
[[Category:Chlorine compounds]]
[[Category:Cosmetics ingredients]]
 
{{Chemical-compound-stub}}
{{medicine-stub}}

Latest revision as of 11:13, 15 February 2025


Chloroacetamide[edit]

Structural formula of Chloroacetamide

Chloroacetamide is an organic compound with the chemical formula C2H4ClNO. It is a member of the class of compounds known as acetamides, which are derivatives of acetic acid where the hydroxyl group is replaced by an amine group. Chloroacetamide is characterized by the presence of a chlorine atom attached to the acetamide moiety.

Chemical Properties[edit]

Chloroacetamide is a white crystalline solid at room temperature. It is soluble in water and various organic solvents. The presence of the chlorine atom in its structure makes it a reactive compound, particularly in nucleophilic substitution reactions.

Synthesis[edit]

Chloroacetamide can be synthesized through the reaction of chloroacetyl chloride with ammonia or an amine. The reaction typically involves the acylation of the amine group, resulting in the formation of the amide bond.

Applications[edit]

Chloroacetamide is used in various industrial applications, primarily as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It serves as a building block for the production of more complex chemical compounds.

Toxicity and Safety[edit]

Chloroacetamide is known to be toxic and should be handled with care. It can cause irritation to the skin, eyes, and respiratory tract. Proper safety measures, including the use of personal protective equipment, should be employed when handling this compound.

Related Compounds[edit]

Related pages[edit]