3-Methyl-GABA: Difference between revisions

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{{Short description|An isomer of the neurotransmitter gamma-aminobutyric acid}}
{{DISPLAYTITLE:3-Methyl-GABA}}
{{DISPLAYTITLE:3-Methyl-GABA}}


'''3-Methyl-GABA''' is a chemical compound that is an isomer of the neurotransmitter [[gamma-aminobutyric acid]] (GABA). It is a derivative of GABA with a methyl group attached to the third carbon of the butyric acid chain. This modification alters its chemical properties and potential biological activity.
== 3-Methyl-GABA ==
[[File:3-Methyl-GABA.svg|thumb|right|Chemical structure of 3-Methyl-GABA]]


==Structure and Properties==
'''3-Methyl-GABA''' (3-methyl gamma-aminobutyric acid) is a [[chemical compound]] that belongs to the class of [[gamma-aminobutyric acid]] (GABA) analogs. It is a derivative of the neurotransmitter GABA, which is the primary inhibitory neurotransmitter in the [[central nervous system]] of [[mammals]].
3-Methyl-GABA is a [[gamma-amino acid]], similar in structure to GABA, but with a methyl group substitution. The presence of the methyl group can influence its interaction with [[GABA receptors]] and its overall pharmacological profile.


==Synthesis==
=== Chemical Structure ===
The synthesis of 3-Methyl-GABA can be achieved through various chemical pathways, often involving the alkylation of GABA or its precursors. The specific methods of synthesis can vary depending on the desired purity and yield.
3-Methyl-GABA is characterized by the addition of a [[methyl group]] at the third carbon of the GABA molecule. This modification alters its [[pharmacological properties]] compared to the parent compound, GABA. The chemical structure of 3-Methyl-GABA is depicted in the adjacent image.


==Biological Activity==
=== Pharmacology ===
As an isomer of GABA, 3-Methyl-GABA may interact with the [[GABAergic system]], which is involved in inhibitory neurotransmission in the [[central nervous system]]. However, the exact biological activity and potential therapeutic applications of 3-Methyl-GABA are subjects of ongoing research.
As a GABA analog, 3-Methyl-GABA interacts with the [[GABA receptor]]s in the brain. However, the presence of the methyl group can affect its binding affinity and efficacy at these receptors. The exact pharmacological effects of 3-Methyl-GABA can vary depending on its interaction with different subtypes of GABA receptors.


==Potential Applications==
=== Potential Applications ===
Research into 3-Methyl-GABA includes its potential use in [[neuroscience]] and [[pharmacology]]. Its unique structure may offer insights into the development of new [[pharmaceuticals]] targeting GABAergic pathways.
Research into GABA analogs like 3-Methyl-GABA is ongoing, with potential applications in the treatment of [[neurological disorders]] such as [[epilepsy]], [[anxiety disorders]], and [[chronic pain]]. The modification of GABA molecules aims to enhance their therapeutic effects while minimizing side effects.


==Related Compounds==
== Related Pages ==
* [[Gamma-aminobutyric acid]] (GABA)
* [[Gamma-aminobutyric acid]]
* [[4-Aminobutyric acid]]
* [[Baclofen]]
 
==Related pages==
* [[GABA receptor]]
* [[GABA receptor]]
* [[Neurotransmitter]]
* [[Neurotransmitter]]
* [[Central nervous system]]
* [[Central nervous system]]


==Gallery==
[[Category:Chemical compounds]]
<gallery>
File:3-Methyl-GABA.svg|Structure of 3-Methyl-GABA
</gallery>
 
[[Category:Gamma-Amino acids]]
[[Category:Neurotransmitters]]
[[Category:Neurotransmitters]]
[[Category:Chemical compounds]]

Latest revision as of 10:51, 15 February 2025


3-Methyl-GABA[edit]

Chemical structure of 3-Methyl-GABA

3-Methyl-GABA (3-methyl gamma-aminobutyric acid) is a chemical compound that belongs to the class of gamma-aminobutyric acid (GABA) analogs. It is a derivative of the neurotransmitter GABA, which is the primary inhibitory neurotransmitter in the central nervous system of mammals.

Chemical Structure[edit]

3-Methyl-GABA is characterized by the addition of a methyl group at the third carbon of the GABA molecule. This modification alters its pharmacological properties compared to the parent compound, GABA. The chemical structure of 3-Methyl-GABA is depicted in the adjacent image.

Pharmacology[edit]

As a GABA analog, 3-Methyl-GABA interacts with the GABA receptors in the brain. However, the presence of the methyl group can affect its binding affinity and efficacy at these receptors. The exact pharmacological effects of 3-Methyl-GABA can vary depending on its interaction with different subtypes of GABA receptors.

Potential Applications[edit]

Research into GABA analogs like 3-Methyl-GABA is ongoing, with potential applications in the treatment of neurological disorders such as epilepsy, anxiety disorders, and chronic pain. The modification of GABA molecules aims to enhance their therapeutic effects while minimizing side effects.

Related Pages[edit]