2C-H: Difference between revisions

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{{Short description|A psychedelic phenethylamine of the 2C family}}
== 2C-H ==
{{Drugbox
| verifiedfields = changed
| verifiedrevid = 477318002
| IUPAC_name = 2-(2,5-Dimethoxyphenyl)ethanamine
| image = 2C-H-Chemdraw.png
| image_size = 200px
}}


'''2C-H''' is a psychedelic phenethylamine of the [[2C (psychedelics)|2C family]]. It is the base compound for a number of other substituted phenethylamines, including the more well-known [[2C-B]] and [[2C-I]].
[[File:2C-H-Chemdraw.png|thumb|right|Chemical structure of 2C-H]]


==Chemical structure==
'''2C-H''' (2,5-dimethoxyphenethylamine) is a [[psychedelic]] [[phenethylamine]] of the 2C family. It is the base compound for a series of psychedelic phenethylamines, which include [[2C-B]], [[2C-I]], and [[2C-E]].
2C-H, or 2-(2,5-dimethoxyphenyl)ethanamine, is a phenethylamine with a methoxy group at the 2 and 5 positions of the benzene ring. The chemical structure of 2C-H serves as a backbone for the synthesis of other compounds in the 2C series.


==Pharmacology==
2C-H is a synthetic compound that was first synthesized by [[Alexander Shulgin]]. It is known for its role as a precursor in the synthesis of other 2C compounds, but it is not commonly used as a recreational drug due to its relatively mild effects compared to its derivatives.
2C-H acts primarily as a [[serotonin receptor]] agonist, particularly at the [[5-HT2A receptor]]. This action is responsible for its psychedelic effects. However, 2C-H itself is not commonly used as a recreational drug due to its relatively mild effects compared to other 2C compounds.


==Synthesis==
== Chemical Properties ==
2C-H can be synthesized from [[2,5-dimethoxybenzaldehyde]] through a series of chemical reactions, including the [[Leuckart reaction]] or reductive amination. It is often used as an intermediate in the synthesis of other 2C compounds.


==Effects==
2C-H is a [[phenethylamine]] with two methoxy groups attached to the benzene ring at the 2 and 5 positions. Its chemical formula is C10H15NO2. The presence of the methoxy groups is a defining feature of the 2C family of compounds.
The effects of 2C-H are not well-documented, as it is not commonly used recreationally. However, it is believed to produce mild psychedelic effects, including altered perception and mood changes.


==Legal status==
== Pharmacology ==
The legal status of 2C-H varies by country. In some jurisdictions, it is classified as a controlled substance, while in others it may be legal or unscheduled. It is important to check local laws before handling or using 2C-H.
 
2C-H acts primarily as a [[serotonin receptor]] agonist, similar to other compounds in the 2C series. However, its affinity for these receptors is lower than that of its more potent derivatives, such as 2C-B and 2C-I. This results in a less intense psychedelic experience.
 
== Synthesis ==
 
2C-H can be synthesized from [[2,5-dimethoxybenzaldehyde]] through a series of chemical reactions. The synthesis typically involves the formation of a nitrostyrene intermediate, which is then reduced to the final phenethylamine product.
 
== Legal Status ==
 
The legal status of 2C-H varies by country. In some jurisdictions, it is classified as a controlled substance due to its structural similarity to other psychoactive compounds. In others, it may be legal or unregulated.
 
== Related Compounds ==
 
2C-H is the parent compound of the 2C series, which includes a variety of other phenethylamines with different substituents on the benzene ring. Some notable derivatives include:


==Related pages==
* [[2C-B]]
* [[2C-B]]
* [[2C-I]]
* [[2C-I]]
* [[2C-E]]
These compounds are known for their psychedelic effects and have been used in both recreational and research settings.
== Related Pages ==
* [[Phenethylamine]]
* [[Phenethylamine]]
* [[Psychedelic drug]]
* [[Psychedelic drug]]
* [[Alexander Shulgin]]


[[Category:Psychedelic phenethylamines]]
[[Category:Psychedelic phenethylamines]]
[[Category:2C (psychedelics)]]
[[Category:Serotonin receptor agonists]]

Latest revision as of 03:40, 13 February 2025

2C-H[edit]

Chemical structure of 2C-H

2C-H (2,5-dimethoxyphenethylamine) is a psychedelic phenethylamine of the 2C family. It is the base compound for a series of psychedelic phenethylamines, which include 2C-B, 2C-I, and 2C-E.

2C-H is a synthetic compound that was first synthesized by Alexander Shulgin. It is known for its role as a precursor in the synthesis of other 2C compounds, but it is not commonly used as a recreational drug due to its relatively mild effects compared to its derivatives.

Chemical Properties[edit]

2C-H is a phenethylamine with two methoxy groups attached to the benzene ring at the 2 and 5 positions. Its chemical formula is C10H15NO2. The presence of the methoxy groups is a defining feature of the 2C family of compounds.

Pharmacology[edit]

2C-H acts primarily as a serotonin receptor agonist, similar to other compounds in the 2C series. However, its affinity for these receptors is lower than that of its more potent derivatives, such as 2C-B and 2C-I. This results in a less intense psychedelic experience.

Synthesis[edit]

2C-H can be synthesized from 2,5-dimethoxybenzaldehyde through a series of chemical reactions. The synthesis typically involves the formation of a nitrostyrene intermediate, which is then reduced to the final phenethylamine product.

Legal Status[edit]

The legal status of 2C-H varies by country. In some jurisdictions, it is classified as a controlled substance due to its structural similarity to other psychoactive compounds. In others, it may be legal or unregulated.

Related Compounds[edit]

2C-H is the parent compound of the 2C series, which includes a variety of other phenethylamines with different substituents on the benzene ring. Some notable derivatives include:

These compounds are known for their psychedelic effects and have been used in both recreational and research settings.

Related Pages[edit]