Iprocrolol: Difference between revisions
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== Iprocrolol == | |||
[[File:Iprocrolol.svg|thumb|right|Chemical structure of Iprocrolol]] | |||
Iprocrolol | |||
'''Iprocrolol''' is a [[beta-adrenergic antagonist]] (commonly known as a beta-blocker) used primarily in the management of [[hypertension]] and certain types of [[cardiac arrhythmias]]. As a member of the beta-blocker class, Iprocrolol functions by blocking the effects of [[epinephrine]] (adrenaline) on the beta-adrenergic receptors, which are part of the [[sympathetic nervous system]]. | |||
Iprocrolol is | |||
== | == Mechanism of Action == | ||
Iprocrolol works by selectively inhibiting the beta-1 adrenergic receptors located primarily in the [[heart]]. This action results in a decrease in heart rate, cardiac output, and the release of [[renin]] from the kidneys. By reducing the heart's workload and oxygen demand, Iprocrolol is effective in treating conditions such as [[angina pectoris]] and [[myocardial infarction]]. | |||
Iprocrolol | |||
== | == Clinical Uses == | ||
* [[Beta | |||
Iprocrolol is indicated for the treatment of: | |||
* [[Hypertension]]: By lowering blood pressure, Iprocrolol helps prevent complications such as [[stroke]] and [[myocardial infarction]]. | |||
* [[Angina]]: It reduces the frequency and severity of angina attacks by decreasing myocardial oxygen demand. | |||
* [[Arrhythmias]]: Iprocrolol is used to manage certain types of arrhythmias by stabilizing the heart's rhythm. | |||
== Side Effects == | |||
Common side effects of Iprocrolol include: | |||
* [[Bradycardia]] (slow heart rate) | |||
* [[Hypotension]] (low blood pressure) | |||
* [[Fatigue]] | |||
* [[Dizziness]] | |||
* [[Cold extremities]] | |||
Less common but serious side effects may include: | |||
* [[Bronchospasm]] in patients with [[asthma]] | |||
* [[Heart failure]] | |||
* [[Depression]] | |||
== Contraindications == | |||
Iprocrolol is contraindicated in patients with: | |||
* [[Asthma]] or severe [[chronic obstructive pulmonary disease]] (COPD) | |||
* [[Bradycardia]] | |||
* [[Heart block]] greater than first degree | |||
* [[Cardiogenic shock]] | |||
== Pharmacokinetics == | |||
Iprocrolol is absorbed well from the gastrointestinal tract and undergoes hepatic metabolism. It has a half-life that allows for once or twice daily dosing, depending on the formulation. The drug is excreted primarily via the kidneys. | |||
== Related Pages == | |||
* [[Beta blocker]] | |||
* [[Hypertension]] | * [[Hypertension]] | ||
* [[ | * [[Cardiac arrhythmia]] | ||
* [[ | * [[Angina pectoris]] | ||
[[Category:Beta blockers]] | [[Category:Beta blockers]] | ||
[[Category: | [[Category:Cardiovascular drugs]] | ||
Latest revision as of 03:29, 13 February 2025
Iprocrolol[edit]
Iprocrolol is a beta-adrenergic antagonist (commonly known as a beta-blocker) used primarily in the management of hypertension and certain types of cardiac arrhythmias. As a member of the beta-blocker class, Iprocrolol functions by blocking the effects of epinephrine (adrenaline) on the beta-adrenergic receptors, which are part of the sympathetic nervous system.
Mechanism of Action[edit]
Iprocrolol works by selectively inhibiting the beta-1 adrenergic receptors located primarily in the heart. This action results in a decrease in heart rate, cardiac output, and the release of renin from the kidneys. By reducing the heart's workload and oxygen demand, Iprocrolol is effective in treating conditions such as angina pectoris and myocardial infarction.
Clinical Uses[edit]
Iprocrolol is indicated for the treatment of:
- Hypertension: By lowering blood pressure, Iprocrolol helps prevent complications such as stroke and myocardial infarction.
- Angina: It reduces the frequency and severity of angina attacks by decreasing myocardial oxygen demand.
- Arrhythmias: Iprocrolol is used to manage certain types of arrhythmias by stabilizing the heart's rhythm.
Side Effects[edit]
Common side effects of Iprocrolol include:
- Bradycardia (slow heart rate)
- Hypotension (low blood pressure)
- Fatigue
- Dizziness
- Cold extremities
Less common but serious side effects may include:
- Bronchospasm in patients with asthma
- Heart failure
- Depression
Contraindications[edit]
Iprocrolol is contraindicated in patients with:
- Asthma or severe chronic obstructive pulmonary disease (COPD)
- Bradycardia
- Heart block greater than first degree
- Cardiogenic shock
Pharmacokinetics[edit]
Iprocrolol is absorbed well from the gastrointestinal tract and undergoes hepatic metabolism. It has a half-life that allows for once or twice daily dosing, depending on the formulation. The drug is excreted primarily via the kidneys.