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= Performance-Enhancing Substances =
Performance-enhancing substance


'''Performance-Enhancing Substances''' (PES), also known as '''Performance-Enhancing Drugs''' (PEDs), refer to a broad category of substances used to improve performance in various human activities. These substances are utilized in sports, academics, and military contexts, among others, to enhance physical or cognitive abilities. While some performance enhancers, like caffeine, are legal and widely accepted, others are banned due to health risks and ethical concerns, particularly in competitive sports.
A '''performance-enhancing substance''' is any substance taken by individuals to improve their performance in a particular activity, often in sports or other competitive fields. These substances can include a wide range of drugs, supplements, and other compounds that are believed to enhance physical or mental capabilities.


== Overview ==
==Types of Performance-enhancing Substances==
Performance-enhancing substances encompass a wide range of drugs and supplements designed to improve physical endurance, strength, or recovery times in athletes and bodybuilders, as well as cognitive function in academic settings. These substances are often subject to controversy and regulation due to their potential health risks and the ethical implications of their use.
Performance-enhancing substances can be broadly categorized into several types:


[[File:Auto Peds LCCN2016826014.jpg|thumb|An athlete undergoing a doping test. (Placeholder image)]]
===Anabolic Steroids===
[[Anabolic steroids]] are synthetic derivatives of testosterone, a male hormone. They are used to increase muscle mass and strength. Common examples include [[nandrolone]] and [[stanozolol]].


<youtube>
===Stimulants===
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[[Stimulants]] are substances that increase alertness, attention, and energy. They can also increase heart rate and blood pressure. Examples include [[amphetamine]] and [[caffeine]].
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[[File:Peds DBS.jpg|thumb|Assorted nootropics, commonly used for cognitive enhancement. (Placeholder image)]]
===Hormones===
Hormones such as [[human growth hormone]] (HGH) and [[erythropoietin]] (EPO) are used to enhance performance by increasing muscle mass or red blood cell production, respectively.


== Types of Performance-Enhancing Substances ==
===Diuretics===
Performance-enhancing substances can be categorized based on their intended effects:
[[Diuretics]] are used to remove excess water from the body and are often used by athletes to make weight in sports with weight classes.


=== Physical Performance Enhancers ===
===Beta-2 Agonists===
* '''Anabolic Steroids:''' Synthetic substances similar to the male sex hormone testosterone, used to increase muscle mass and strength.
[[Beta-2 agonists]] are used to increase muscle mass and reduce body fat. They are often used in the treatment of asthma but can be abused for performance enhancement.
* '''Erythropoietin (EPO):''' A hormone that increases red blood cell production, enhancing oxygen delivery to muscles and improving endurance.
* '''Beta-2 Agonists:''' Compounds that can increase muscle mass and reduce body fat.
* '''Creatine:''' A dietary supplement that can improve muscle mass and enhance short-term performance in high-intensity activities.


=== Cognitive Enhancers ===
===Nootropics===
* '''Nootropics:''' Substances that improve cognitive function, particularly executive functions, memory, creativity, or motivation.
[[Nootropics]], also known as "smart drugs," are substances that are claimed to improve cognitive function, particularly executive functions, memory, creativity, or motivation.
* '''Stimulants:''' Drugs such as amphetamines and caffeine, which can increase alertness, attention, and energy.


== Ethical and Health Concerns ==
==Mechanism of Action==
The use of banned PEDs in sports, known as doping, is considered unethical due to the unfair advantage it provides and the potential for serious health risks. Health risks associated with PEDs include heart problems, liver damage, hormonal imbalances, and psychological effects. Cognitive enhancers, while less regulated, can also pose risks of dependency, psychological issues, and physical side effects.
The mechanisms by which performance-enhancing substances work vary depending on the type of substance:


== Regulation and Testing ==
* '''[[Anabolic steroids]]''' increase protein synthesis within cells, leading to the buildup of cellular tissue, especially in muscles.
In sports, organizations such as the World Anti-Doping Agency (WADA) establish rules and conduct testing to prevent doping. In academic and military settings, the regulation of cognitive enhancers varies widely, with ongoing debate about the ethics of their use.
* '''[[Stimulants]]''' increase the levels of certain neurotransmitters in the brain, enhancing alertness and energy.
* '''[[Hormones]]''' like HGH stimulate growth, cell reproduction, and regeneration, while EPO increases the oxygen-carrying capacity of the blood.
* '''[[Diuretics]]''' increase the excretion of water and salts from the body, reducing body weight.
* '''[[Beta-2 agonists]]''' relax muscles of the airways, increasing airflow to the lungs and sometimes increasing muscle mass.
* '''[[Nootropics]]''' may enhance brain function by increasing blood flow to the brain or altering neurotransmitter levels.


== In Popular Culture ==
==Health Risks==
Performance-enhancing substances have made their way into popular culture, often highlighted in films, documentaries, and books that explore the pressures athletes face to excel and the lengths to which some will go to achieve success.
The use of performance-enhancing substances can pose significant health risks, including:


== External Links ==
* '''[[Cardiovascular issues]]''': Increased risk of heart attack, stroke, and hypertension.
* [https://www.wada-ama.org World Anti-Doping Agency (WADA)]
* '''[[Liver damage]]''': Particularly with oral anabolic steroids.
* [https://www.drugabuse.gov National Institute on Drug Abuse: Steroids and Other Appearance and Performance Enhancing Drugs]
* '''[[Hormonal imbalances]]''': Leading to conditions such as gynecomastia in men and virilization in women.
* '''[[Psychiatric effects]]''': Including aggression, mood swings, and depression.
* '''[[Addiction]]''': Some substances can be addictive, leading to dependency.
 
==Legal and Ethical Considerations==
The use of performance-enhancing substances is banned in most professional sports. Organizations such as the [[World Anti-Doping Agency]] (WADA) have established strict guidelines and testing procedures to prevent their use. Ethical concerns include fairness in competition and the potential for coercion of athletes to use these substances to remain competitive.
 
==Also see==
* [[Doping in sport]]
* [[World Anti-Doping Agency]]
* [[Anabolic steroid]]
* [[Human growth hormone]]
* [[Erythropoietin]]
 
{{Medical disclaimer}}


[[Category:Pharmacology]]
[[Category:Pharmacology]]
[[Category:Sports science]]
[[Category:Sports medicine]]
[[Category:Cognitive enhancers]]
[[Category:Substance abuse]]
[[Category:Ethics in sports]]
 
{{stub}}

Latest revision as of 23:50, 11 December 2024

Performance-enhancing substance

A performance-enhancing substance is any substance taken by individuals to improve their performance in a particular activity, often in sports or other competitive fields. These substances can include a wide range of drugs, supplements, and other compounds that are believed to enhance physical or mental capabilities.

Types of Performance-enhancing Substances[edit]

Performance-enhancing substances can be broadly categorized into several types:

Anabolic Steroids[edit]

Anabolic steroids are synthetic derivatives of testosterone, a male hormone. They are used to increase muscle mass and strength. Common examples include nandrolone and stanozolol.

Stimulants[edit]

Stimulants are substances that increase alertness, attention, and energy. They can also increase heart rate and blood pressure. Examples include amphetamine and caffeine.

Hormones[edit]

Hormones such as human growth hormone (HGH) and erythropoietin (EPO) are used to enhance performance by increasing muscle mass or red blood cell production, respectively.

Diuretics[edit]

Diuretics are used to remove excess water from the body and are often used by athletes to make weight in sports with weight classes.

Beta-2 Agonists[edit]

Beta-2 agonists are used to increase muscle mass and reduce body fat. They are often used in the treatment of asthma but can be abused for performance enhancement.

Nootropics[edit]

Nootropics, also known as "smart drugs," are substances that are claimed to improve cognitive function, particularly executive functions, memory, creativity, or motivation.

Mechanism of Action[edit]

The mechanisms by which performance-enhancing substances work vary depending on the type of substance:

  • Anabolic steroids increase protein synthesis within cells, leading to the buildup of cellular tissue, especially in muscles.
  • Stimulants increase the levels of certain neurotransmitters in the brain, enhancing alertness and energy.
  • Hormones like HGH stimulate growth, cell reproduction, and regeneration, while EPO increases the oxygen-carrying capacity of the blood.
  • Diuretics increase the excretion of water and salts from the body, reducing body weight.
  • Beta-2 agonists relax muscles of the airways, increasing airflow to the lungs and sometimes increasing muscle mass.
  • Nootropics may enhance brain function by increasing blood flow to the brain or altering neurotransmitter levels.

Health Risks[edit]

The use of performance-enhancing substances can pose significant health risks, including:

Legal and Ethical Considerations[edit]

The use of performance-enhancing substances is banned in most professional sports. Organizations such as the World Anti-Doping Agency (WADA) have established strict guidelines and testing procedures to prevent their use. Ethical concerns include fairness in competition and the potential for coercion of athletes to use these substances to remain competitive.

Also see[edit]



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