Endometrial hyperplasia: Difference between revisions
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{{Infobox medical condition | |||
| name = Endometrial hyperplasia | |||
| image = [[File:Simple_endometrial_hyperplasia_-_low_mag.jpg|250px]] | |||
| caption = Micrograph of simple endometrial hyperplasia | |||
| field = [[Gynecology]] | |||
| synonyms = | |||
| symptoms = [[Abnormal uterine bleeding]], [[menorrhagia]], [[metrorrhagia]] | |||
| complications = [[Endometrial cancer]] | |||
| onset = | |||
| duration = | |||
| types = Simple, Complex, Atypical | |||
| causes = [[Estrogen]] excess, [[obesity]], [[polycystic ovary syndrome]] | |||
| risks = [[Obesity]], [[anovulation]], [[hormone replacement therapy]] | |||
| diagnosis = [[Endometrial biopsy]], [[transvaginal ultrasound]] | |||
| differential = [[Endometrial cancer]], [[endometrial polyp]], [[leiomyoma]] | |||
| prevention = [[Weight loss]], [[progestin therapy]] | |||
| treatment = [[Progestin therapy]], [[hysterectomy]] | |||
| medication = [[Progestin]] | |||
| prognosis = Generally good with treatment | |||
| frequency = Common in [[postmenopausal women]] | |||
}} | |||
'''Endometrial Hyperplasia''' is a condition characterized by the excessive thickening of the [[endometrium]], the inner lining of the [[uterus]]. This condition is often caused by an imbalance of the hormones [[estrogen]] and [[progesterone]], with an excess of estrogen stimulating the endometrium to grow and thicken. | '''Endometrial Hyperplasia''' is a condition characterized by the excessive thickening of the [[endometrium]], the inner lining of the [[uterus]]. This condition is often caused by an imbalance of the hormones [[estrogen]] and [[progesterone]], with an excess of estrogen stimulating the endometrium to grow and thicken. | ||
== Causes == | == Causes == | ||
Endometrial hyperplasia is most commonly caused by an excess of estrogen without progesterone. This can occur for a variety of reasons, including [[obesity]], [[polycystic ovary syndrome]], [[menopause]], and certain medications. In rare cases, it can also be caused by an ovarian tumor that produces estrogen. | Endometrial hyperplasia is most commonly caused by an excess of estrogen without progesterone. This can occur for a variety of reasons, including [[obesity]], [[polycystic ovary syndrome]], [[menopause]], and certain medications. In rare cases, it can also be caused by an ovarian tumor that produces estrogen. | ||
== Symptoms == | == Symptoms == | ||
The most common symptom of endometrial hyperplasia is abnormal [[uterine bleeding]], which can manifest as heavy or prolonged periods, bleeding between periods, or postmenopausal bleeding. Other symptoms can include [[pain]] during sex or pelvic pain. | The most common symptom of endometrial hyperplasia is abnormal [[uterine bleeding]], which can manifest as heavy or prolonged periods, bleeding between periods, or postmenopausal bleeding. Other symptoms can include [[pain]] during sex or pelvic pain. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of endometrial hyperplasia typically involves a [[pelvic exam]], [[ultrasound]], and an [[endometrial biopsy]]. In some cases, a [[hysteroscopy]] may be performed to examine the inside of the uterus. | Diagnosis of endometrial hyperplasia typically involves a [[pelvic exam]], [[ultrasound]], and an [[endometrial biopsy]]. In some cases, a [[hysteroscopy]] may be performed to examine the inside of the uterus. | ||
== Treatment == | == Treatment == | ||
Treatment for endometrial hyperplasia depends on the cause of the condition, the severity of symptoms, and the patient's overall health. Treatment options can include hormonal therapy, such as progesterone, to balance the levels of hormones in the body, or surgery to remove the thickened endometrial tissue. | Treatment for endometrial hyperplasia depends on the cause of the condition, the severity of symptoms, and the patient's overall health. Treatment options can include hormonal therapy, such as progesterone, to balance the levels of hormones in the body, or surgery to remove the thickened endometrial tissue. | ||
== Prognosis == | == Prognosis == | ||
With proper treatment, the prognosis for endometrial hyperplasia is generally good. However, if left untreated, it can lead to [[endometrial cancer]], so it is important to seek medical attention if symptoms are present. | With proper treatment, the prognosis for endometrial hyperplasia is generally good. However, if left untreated, it can lead to [[endometrial cancer]], so it is important to seek medical attention if symptoms are present. | ||
== Endometrial_hyperplasia images== | |||
<gallery> | |||
File:Histopathology_of_complex_hyperplasia_without_atypia.jpg|Histopathology of complex hyperplasia without atypia | |||
File:Histopathology_of_complex_hyperplasia_with_atypia.jpg|Histopathology of complex hyperplasia with atypia | |||
</gallery> | |||
== See Also == | == See Also == | ||
* [[Endometrial cancer]] | * [[Endometrial cancer]] | ||
* [[Menopause]] | * [[Menopause]] | ||
* [[Polycystic ovary syndrome]] | * [[Polycystic ovary syndrome]] | ||
* [[Uterine bleeding]] | * [[Uterine bleeding]] | ||
[[Category:Women's Health]] | [[Category:Women's Health]] | ||
[[Category:Gynecological Conditions]] | [[Category:Gynecological Conditions]] | ||
[[Category:Endocrine Disorders]] | [[Category:Endocrine Disorders]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 15:19, 6 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Endometrial hyperplasia | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Abnormal uterine bleeding, menorrhagia, metrorrhagia |
| Complications | Endometrial cancer |
| Onset | |
| Duration | |
| Types | Simple, Complex, Atypical |
| Causes | Estrogen excess, obesity, polycystic ovary syndrome |
| Risks | Obesity, anovulation, hormone replacement therapy |
| Diagnosis | Endometrial biopsy, transvaginal ultrasound |
| Differential diagnosis | Endometrial cancer, endometrial polyp, leiomyoma |
| Prevention | Weight loss, progestin therapy |
| Treatment | Progestin therapy, hysterectomy |
| Medication | Progestin |
| Prognosis | Generally good with treatment |
| Frequency | Common in postmenopausal women |
| Deaths | N/A |
Endometrial Hyperplasia is a condition characterized by the excessive thickening of the endometrium, the inner lining of the uterus. This condition is often caused by an imbalance of the hormones estrogen and progesterone, with an excess of estrogen stimulating the endometrium to grow and thicken.
Causes[edit]
Endometrial hyperplasia is most commonly caused by an excess of estrogen without progesterone. This can occur for a variety of reasons, including obesity, polycystic ovary syndrome, menopause, and certain medications. In rare cases, it can also be caused by an ovarian tumor that produces estrogen.
Symptoms[edit]
The most common symptom of endometrial hyperplasia is abnormal uterine bleeding, which can manifest as heavy or prolonged periods, bleeding between periods, or postmenopausal bleeding. Other symptoms can include pain during sex or pelvic pain.
Diagnosis[edit]
Diagnosis of endometrial hyperplasia typically involves a pelvic exam, ultrasound, and an endometrial biopsy. In some cases, a hysteroscopy may be performed to examine the inside of the uterus.
Treatment[edit]
Treatment for endometrial hyperplasia depends on the cause of the condition, the severity of symptoms, and the patient's overall health. Treatment options can include hormonal therapy, such as progesterone, to balance the levels of hormones in the body, or surgery to remove the thickened endometrial tissue.
Prognosis[edit]
With proper treatment, the prognosis for endometrial hyperplasia is generally good. However, if left untreated, it can lead to endometrial cancer, so it is important to seek medical attention if symptoms are present.
Endometrial_hyperplasia images[edit]
-
Histopathology of complex hyperplasia without atypia
-
Histopathology of complex hyperplasia with atypia


