Deschloroketamine: Difference between revisions

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'''Deschloroketamine''' (also known as '''2'-Oxo-PCM''', '''DXE''', '''DCK''', or '''Deschloroketamine''') is a synthetic dissociative of the arylcyclohexylamine class. It is a research chemical that is often used in scientific and medical research.  
== Deschloroketamine ==
 
[[File:Deschloroketamine.png|Deschloroketamine chemical structure|thumb|right]]
 
'''Deschloroketamine''' (also known as '''2'-Oxo-PCM''', '''DXE''', or '''DCK''') is a dissociative anesthetic that belongs to the [[arylcyclohexylamine]] class. It is structurally related to [[ketamine]], a well-known anesthetic, but lacks the chlorine atom present in ketamine, which is reflected in its name.
 
== Chemical Structure and Properties ==
 
Deschloroketamine is chemically known as 2-(methylamino)-2-phenylcyclohexanone. It is a derivative of [[ketamine]], where the chlorine atom on the phenyl ring is removed. This modification results in a compound with similar but distinct pharmacological properties compared to ketamine.
 
[[File:Deschloroketamine3d.png|Deschloroketamine 3D molecular structure|thumb|left]]
 
The molecular formula of deschloroketamine is C<sub>13</sub>H<sub>17</sub>NO, and it has a molar mass of 203.28 g/mol. The compound is typically encountered as a white crystalline powder.
 
== Pharmacology ==
 
Deschloroketamine acts primarily as an [[NMDA receptor antagonist]], similar to ketamine. This action is responsible for its dissociative effects, which include alterations in perception, mood, and consciousness. The compound may also interact with other receptor systems, contributing to its complex pharmacological profile.
 
== Effects and Uses ==


==Chemistry==
Deschloroketamine is known for its dissociative effects, which can include sensory detachment, hallucinations, and altered perception of time and space. These effects are dose-dependent and can vary significantly between individuals.


Deschloroketamine is an [[Arylcyclohexylamine|arylcylohexylamine]] class compound. Arylcyclohexylamines are named for their structures which include a cyclohexane ring bound to an aromatic ring along with an amine group. Deschloroketamine contains a phenyl ring bonded to a cyclohexane ring. An amino methyl chain (-N-CH3) is bound to the same carbon of the cyclohexane ring as the ketone group. Deschloroketamine is a chiral molecule and is often produced as a racemate.
In a clinical context, deschloroketamine has been explored for its potential use as an anesthetic, although it is not as widely used as ketamine. Its use in research settings has been limited, and it is more commonly encountered as a recreational drug.


==Pharmacology==
== Legal Status ==


Deschloroketamine acts primarily as an [[NMDA receptor|NMDA receptor antagonist]]. NMDA receptors allow for electrical signals to pass between neurons in the brain and spinal column; for the signals to pass, the receptor must be open. Dissociatives close the NMDA receptors by blocking them. This disconnection of neurons leads to loss of feeling, difficulty moving, and eventually the "K-hole" or an intense and unpleasant feeling of dissociation.
The legal status of deschloroketamine varies by country. In some jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of approved medical use. In others, it may be available for research purposes under specific regulations.


==Effects==
== Safety and Risks ==


The effects of Deschloroketamine are similar to other dissociative anesthetics such as [[Ketamine|ketamine]] and [[Phencyclidine|phencyclidine]] (PCP). These effects include analgesia, anesthesia, hallucinations, and a feeling of disconnection from one's physical body.  
As with other dissociative anesthetics, the use of deschloroketamine carries risks, including the potential for psychological dependence, cognitive impairment, and adverse physical effects. Users may experience confusion, agitation, and in some cases, psychosis. Long-term use can lead to bladder and kidney damage, a condition known as ketamine bladder syndrome.


==Legality==
== Related Compounds ==


The legality of Deschloroketamine varies by country. In some countries, it is a controlled substance, while in others it is legal to possess for personal use.
Deschloroketamine is part of a broader class of arylcyclohexylamines, which includes:


==Safety==
* [[Ketamine]]
* [[Methoxetamine]]
* [[Phencyclidine]] (PCP)


As with all substances, the safety of Deschloroketamine depends on various factors including the dose, the user's health, and the context in which it's used. It is recommended that Deschloroketamine be used in a safe, controlled environment, and that users have a sober person present to assist in case of emergencies.
== Related Pages ==


==See also==
* [[Dissociative]]
* [[Arylcyclohexylamine]]
* [[Ketamine]]
* [[Ketamine]]
* [[Phencyclidine]]
* [[NMDA receptor antagonist]]
* [[Dissociative drug]]
 
{{Psychoactive drugs}}
{{Dissociatives}}


[[Category:Psychoactive drugs]]
[[Category:Dissociative drugs]]
[[Category:Dissociative drugs]]
[[Category:Arylcyclohexylamines]]
[[Category:Arylcyclohexylamines]]
{{Psychoactive substance}}
[[Category:NMDA receptor antagonists]]
{{medicine-stub}}
== Deschloroketamine ==
<gallery>
File:Deschloroketamine.png|Deschloroketamine
File:Deschloroketamine3d.png|Deschloroketamine 3D
</gallery>
== Deschloroketamine ==
<gallery>
File:Deschloroketamine.png|Deschloroketamine
File:Deschloroketamine3d.png|Deschloroketamine 3D
</gallery>

Latest revision as of 18:52, 23 March 2025

Deschloroketamine[edit]

Deschloroketamine chemical structure

Deschloroketamine (also known as 2'-Oxo-PCM, DXE, or DCK) is a dissociative anesthetic that belongs to the arylcyclohexylamine class. It is structurally related to ketamine, a well-known anesthetic, but lacks the chlorine atom present in ketamine, which is reflected in its name.

Chemical Structure and Properties[edit]

Deschloroketamine is chemically known as 2-(methylamino)-2-phenylcyclohexanone. It is a derivative of ketamine, where the chlorine atom on the phenyl ring is removed. This modification results in a compound with similar but distinct pharmacological properties compared to ketamine.

Deschloroketamine 3D molecular structure

The molecular formula of deschloroketamine is C13H17NO, and it has a molar mass of 203.28 g/mol. The compound is typically encountered as a white crystalline powder.

Pharmacology[edit]

Deschloroketamine acts primarily as an NMDA receptor antagonist, similar to ketamine. This action is responsible for its dissociative effects, which include alterations in perception, mood, and consciousness. The compound may also interact with other receptor systems, contributing to its complex pharmacological profile.

Effects and Uses[edit]

Deschloroketamine is known for its dissociative effects, which can include sensory detachment, hallucinations, and altered perception of time and space. These effects are dose-dependent and can vary significantly between individuals.

In a clinical context, deschloroketamine has been explored for its potential use as an anesthetic, although it is not as widely used as ketamine. Its use in research settings has been limited, and it is more commonly encountered as a recreational drug.

Legal Status[edit]

The legal status of deschloroketamine varies by country. In some jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of approved medical use. In others, it may be available for research purposes under specific regulations.

Safety and Risks[edit]

As with other dissociative anesthetics, the use of deschloroketamine carries risks, including the potential for psychological dependence, cognitive impairment, and adverse physical effects. Users may experience confusion, agitation, and in some cases, psychosis. Long-term use can lead to bladder and kidney damage, a condition known as ketamine bladder syndrome.

Related Compounds[edit]

Deschloroketamine is part of a broader class of arylcyclohexylamines, which includes:

Related Pages[edit]




Template:Dissociatives