Apocrine gland carcinoma: Difference between revisions
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{{SI}} | |||
{{Infobox medical condition | |||
[[File:SkinTumors-P8120605.JPG|thumb| | | name = Apocrine gland carcinoma | ||
| image = [[File:SkinTumors-P8120605.JPG|left|thumb|Apocrine gland carcinoma]] | |||
| caption = Apocrine gland carcinoma | |||
| field = [[Oncology]] | |||
| synonyms = Apocrine adenocarcinoma | |||
| symptoms = [[Skin lesion]], [[nodule]], [[ulcer]] | |||
| complications = [[Metastasis]] | |||
| onset = Typically in adults | |||
| duration = Chronic | |||
| causes = Unknown | |||
| risks = [[Genetic predisposition]], [[radiation exposure]] | |||
| diagnosis = [[Biopsy]], [[histopathology]] | |||
| differential = [[Basal cell carcinoma]], [[squamous cell carcinoma]], [[sebaceous carcinoma]] | |||
| treatment = [[Surgical excision]], [[radiation therapy]], [[chemotherapy]] | |||
| prognosis = Variable, depends on stage and metastasis | |||
| frequency = Rare | |||
}} | |||
'''Apocrine gland carcinoma''' is a rare type of [[malignant tumor]] that arises from the [[apocrine glands]], which are specialized [[sweat glands]] found primarily in the [[axilla]], [[anogenital region]], and the [[areola]] of the [[breast]]. These glands are responsible for secreting a milky fluid that is part of the body's [[sweat]] and [[pheromone]] production. | '''Apocrine gland carcinoma''' is a rare type of [[malignant tumor]] that arises from the [[apocrine glands]], which are specialized [[sweat glands]] found primarily in the [[axilla]], [[anogenital region]], and the [[areola]] of the [[breast]]. These glands are responsible for secreting a milky fluid that is part of the body's [[sweat]] and [[pheromone]] production. | ||
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The prognosis for apocrine gland carcinoma varies depending on the stage at diagnosis and the presence of metastasis. Early-stage tumors that are completely excised have a better prognosis, while advanced cases with regional or distant metastasis may have a poorer outcome. | The prognosis for apocrine gland carcinoma varies depending on the stage at diagnosis and the presence of metastasis. Early-stage tumors that are completely excised have a better prognosis, while advanced cases with regional or distant metastasis may have a poorer outcome. | ||
== | == See also == | ||
* [[Sweat gland]] | * [[Sweat gland]] | ||
* [[Skin cancer]] | * [[Skin cancer]] | ||
Latest revision as of 15:43, 4 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Apocrine gland carcinoma | |
|---|---|
 | |
| Synonyms | Apocrine adenocarcinoma |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Skin lesion, nodule, ulcer |
| Complications | Metastasis |
| Onset | Typically in adults |
| Duration | Chronic |
| Types | N/A |
| Causes | Unknown |
| Risks | Genetic predisposition, radiation exposure |
| Diagnosis | Biopsy, histopathology |
| Differential diagnosis | Basal cell carcinoma, squamous cell carcinoma, sebaceous carcinoma |
| Prevention | N/A |
| Treatment | Surgical excision, radiation therapy, chemotherapy |
| Medication | N/A |
| Prognosis | Variable, depends on stage and metastasis |
| Frequency | Rare |
| Deaths | N/A |
Apocrine gland carcinoma is a rare type of malignant tumor that arises from the apocrine glands, which are specialized sweat glands found primarily in the axilla, anogenital region, and the areola of the breast. These glands are responsible for secreting a milky fluid that is part of the body's sweat and pheromone production.
Pathophysiology[edit]
Apocrine gland carcinoma is characterized by the uncontrolled growth of cells originating from the apocrine glands. These tumors can exhibit a variety of histological patterns, often resembling other types of adenocarcinoma. The tumor cells typically show apocrine differentiation, which can be identified by their large size, abundant eosinophilic cytoplasm, and prominent nucleoli.
Clinical Presentation[edit]
Patients with apocrine gland carcinoma may present with a palpable mass in areas where apocrine glands are located, such as the axilla or the groin. The mass may be painful or tender, and in some cases, ulceration or discharge may be present. Due to its rarity, apocrine gland carcinoma is often misdiagnosed as other more common skin conditions.
Diagnosis[edit]
The diagnosis of apocrine gland carcinoma is primarily based on histopathological examination. A biopsy of the lesion is performed, and the tissue is examined under a microscope. Immunohistochemical staining can help differentiate apocrine gland carcinoma from other types of skin cancers by highlighting specific markers associated with apocrine differentiation.
Treatment[edit]
The primary treatment for apocrine gland carcinoma is surgical excision with clear margins. Depending on the stage and location of the tumor, additional treatments such as radiation therapy or chemotherapy may be considered. Due to the potential for local recurrence and metastasis, regular follow-up is essential.
Prognosis[edit]
The prognosis for apocrine gland carcinoma varies depending on the stage at diagnosis and the presence of metastasis. Early-stage tumors that are completely excised have a better prognosis, while advanced cases with regional or distant metastasis may have a poorer outcome.
