ADB-BINACA: Difference between revisions

From WikiMD's Wellness Encyclopedia

CSV import
 
CSV import
Tags: mobile edit mobile web edit
 
Line 1: Line 1:
{{Short description|Synthetic cannabinoid}}
== ADB-BINACA ==
{{Drugbox
| verifiedfields = changed
| verifiedrevid = 477002547
| image = ADB-BINACA_structure.png
| image_size = 200px
| IUPAC_name = N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-butyl-1H-indazole-3-carboxamide
| CAS_number = 1185887-21-1
| ChemSpiderID = 58191434
| UNII = 7J1X0R8F3V
| PubChem = 11902592
| C=18
| H=26
| N=4
| O=2
| smiles = CCCN1C=C(C2=NN=C(C=C2)C1=O)C(=O)NC(C)(C)C(C)N
}}


'''ADB-BINACA''' is a synthetic [[cannabinoid]] that has been used in [[synthetic cannabis]] products. It is a potent agonist of the [[cannabinoid receptor]]s, specifically the [[CB1 receptor]].
[[File:ADB-BINACA_structure.png|thumb|right|Chemical structure of ADB-BINACA]]


==Chemical structure and properties==
'''ADB-BINACA''' is a synthetic cannabinoid that has been used as a designer drug. It is a potent agonist of the [[cannabinoid receptor]]s, which are part of the [[endocannabinoid system]] in the human body. ADB-BINACA is often found in "[[spice (drug)|spice]]" or "[[K2 (drug)|K2]]" products, which are marketed as legal alternatives to [[cannabis]].
ADB-BINACA is classified as an indazole-based synthetic cannabinoid. Its chemical structure includes an indazole core, which is a bicyclic structure composed of a benzene ring fused to a pyrazole ring. The compound is further characterized by a carboxamide group at the 3-position of the indazole ring, and a butyl chain at the 1-position.


The IUPAC name for ADB-BINACA is N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-butyl-1H-indazole-3-carboxamide. The presence of the tert-leucine moiety in its structure is a distinguishing feature, contributing to its high affinity for cannabinoid receptors.
== Chemical Structure ==


==Pharmacology==
ADB-BINACA is classified as an indazole-based synthetic cannabinoid. Its chemical structure includes an indazole core, which is a bicyclic structure composed of a benzene ring fused to a pyrazole ring. The compound also contains an amide linkage and a tert-butyl group, which contribute to its high affinity for cannabinoid receptors.
ADB-BINACA acts as a potent agonist at the CB1 receptor, which is primarily responsible for the psychoactive effects of cannabinoids. The activation of CB1 receptors by ADB-BINACA can lead to effects similar to those of [[tetrahydrocannabinol]] (THC), the primary psychoactive component of [[cannabis]].


The compound's high potency and efficacy at the CB1 receptor make it a subject of concern for public health, as it can lead to severe adverse effects, including [[psychosis]], [[tachycardia]], and [[hypertension]].
== Pharmacology ==


==Legal status==
ADB-BINACA acts as a full agonist at the [[CB1 receptor|CB1]] and [[CB2 receptor|CB2]] cannabinoid receptors. These receptors are part of the [[G protein-coupled receptor]] family and are primarily involved in the modulation of neurotransmitter release in the [[central nervous system]]. The activation of these receptors by ADB-BINACA can lead to psychoactive effects similar to those of [[tetrahydrocannabinol]] (THC), the primary active component of cannabis.
Due to its potential for abuse and adverse health effects, ADB-BINACA has been classified as a controlled substance in several countries. Regulatory agencies have placed it under various schedules to restrict its distribution and use.


==Synthesis==
== Legal Status ==
The synthesis of ADB-BINACA involves the formation of the indazole core, followed by the introduction of the carboxamide group and the butyl chain. The synthesis process requires careful control of reaction conditions to ensure the correct formation of the desired isomer.


==Health effects==
Due to its potential for abuse and lack of medical use, ADB-BINACA has been classified as a controlled substance in many countries. The legal status of synthetic cannabinoids like ADB-BINACA varies widely, with some jurisdictions implementing blanket bans on entire classes of compounds to prevent the proliferation of new designer drugs.
The use of ADB-BINACA has been associated with a range of adverse health effects. Users may experience symptoms such as [[anxiety]], [[paranoia]], [[hallucinations]], and [[seizures]]. The compound's high potency increases the risk of overdose and severe toxicological outcomes.
 
== Health Effects ==
 
The use of ADB-BINACA has been associated with a range of adverse health effects. These can include [[tachycardia]], [[hypertension]], [[nausea]], [[vomiting]], [[anxiety]], and [[hallucinations]]. In severe cases, the use of synthetic cannabinoids can lead to [[seizures]], [[renal failure]], and even [[death]].
 
== Related Pages ==


==Related pages==
* [[Synthetic cannabinoids]]
* [[Synthetic cannabinoids]]
* [[Cannabinoid receptor]]
* [[Cannabinoid receptor]]
* [[Tetrahydrocannabinol]]
* [[Endocannabinoid system]]
* [[Synthetic cannabis]]
* [[Spice (drug)]]
* [[K2 (drug)]]


[[Category:Synthetic cannabinoids]]
[[Category:Synthetic cannabinoids]]
[[Category:Indazolecarboxamides]]
[[Category:Designer drugs]]
[[Category:Designer drugs]]

Latest revision as of 11:49, 15 February 2025

ADB-BINACA[edit]

Chemical structure of ADB-BINACA

ADB-BINACA is a synthetic cannabinoid that has been used as a designer drug. It is a potent agonist of the cannabinoid receptors, which are part of the endocannabinoid system in the human body. ADB-BINACA is often found in "spice" or "K2" products, which are marketed as legal alternatives to cannabis.

Chemical Structure[edit]

ADB-BINACA is classified as an indazole-based synthetic cannabinoid. Its chemical structure includes an indazole core, which is a bicyclic structure composed of a benzene ring fused to a pyrazole ring. The compound also contains an amide linkage and a tert-butyl group, which contribute to its high affinity for cannabinoid receptors.

Pharmacology[edit]

ADB-BINACA acts as a full agonist at the CB1 and CB2 cannabinoid receptors. These receptors are part of the G protein-coupled receptor family and are primarily involved in the modulation of neurotransmitter release in the central nervous system. The activation of these receptors by ADB-BINACA can lead to psychoactive effects similar to those of tetrahydrocannabinol (THC), the primary active component of cannabis.

Legal Status[edit]

Due to its potential for abuse and lack of medical use, ADB-BINACA has been classified as a controlled substance in many countries. The legal status of synthetic cannabinoids like ADB-BINACA varies widely, with some jurisdictions implementing blanket bans on entire classes of compounds to prevent the proliferation of new designer drugs.

Health Effects[edit]

The use of ADB-BINACA has been associated with a range of adverse health effects. These can include tachycardia, hypertension, nausea, vomiting, anxiety, and hallucinations. In severe cases, the use of synthetic cannabinoids can lead to seizures, renal failure, and even death.

Related Pages[edit]

Retrieved from "https://wikimd.com/index.php?title=ADB-BINACA&oldid=6297035"